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63 results for “Synovial Fluid”
Antibodies to Borrelia burgdorferi and Bartonella species in serum and synovial fluid from people with rheumatic diseases
<p>Vector-borne infections may underlie some rheumatic diseases, particularly in people with joint effusions. The aim of this study was to compare serum and synovial fluid antibodies to<em> B. burgdorferi </em>and <em>Bartonella </em>spp. in patients with rheumatic diseases.</p> <p>This observational, cross-sectional study examined paired synovial fluid and serum specimens collected from 110 patients with joint effusion between October 2017 and January 2022. Testing for antibodies to <em>B. burgdorferi </em>(using CDC criteria) and <em>Bartonella </em>spp. via two Indirect Fluorescent Antibody [IFA] assays, was performed as part of routine patient care.</p> <p>There were 30 participants (27%) with positive two-tier <em>B. burgdorferi</em> serology, and 26 participants (24%) with IFA seroreactivity (≥1:256) to <em>B. henselae </em>and/or <em>B. quintana. </em>Both <em>B. burgdorferi</em> IgM and IgG were detected more frequently in synovial fluid than serum: 27% of patients were either IgM or IgG positive in synovial fluid, compared to 15.5% in serum (p = 0.048). Conversely, <em>B. henselae </em>and <em>B. quintana </em>antibodies were detected more frequently in serum than synovial fluid; overall only 2% of patients had positive IFA titers in synovial fluid, compared to 24% who had positive IFA titers in serum (p <0.001). There were no significant associations between <em>B. burgdorferi</em> or <em>Bartonella</em> spp. seroreactivity with any of the clinical rheumatological diagnoses.</p> <p>This study provides preliminary support for the importance of synovial fluid antibody testing for documenting exposure to <em>B. burgdorferi</em>, but not for documenting exposure to <em>Bartonella </em>spp.</p>
Antibodies to Borrelia burgdorferi and Bartonella species in serum and synovial fluid from people with rheumatic diseases
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Supplementary datasets from: The wettability of electron spun membranes by synovial fluid
<p>Aseptic loosening due to periprosthetic osteolysis has been accepted as one of the leading causes of revision procedures in patients with previous joint arthroplasty. Recently, several strategies for suppression of osteolysis were proposed, mostly based on biological treatment such as mitigation of chronic inflammatory reactions. However, these biological treatments do not stop the debris migration but only reduce the inflammatory reaction. To address this shortcoming, we propose the concept of ultrahigh molecular weighted polyethylene (UHMWPE) particles filtration-storage by electrospun membranes. Firstly, the surface tension of synovial fluid is obtained by use of a pendant droplet. Secondly, the contact angle of the electrospun membranes wetted by two different liquids is measured to obtain the free surface energy using of the Owens-Wendt model. Additionally, the wettability of electrospun membranes by synovial fluid as a function of technology parameters is studied.</p>
Mononuclear cells from blood and synovial fluids of ankylosing spondilitis paitents
<p>This record deposits the scRNA-seq data of mononuclear cells from blood and synovial fluids of ankylosing spondilitis paitents. Samples of two donors were subject to CD3- live cells sorting enrichment therefore excluding T cells.</p>
Synovial Fluid Bank From Arthritic Patients
ClinicalTrials.gov study NCT00512343. IPD Sharing: NO. Countries: 1. Publications: 2.
Supplementary datasets from: The wettability of electron spun membranes by synovial fluid
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Supporting data files: Exploring the early molecular pathogenesis of osteoarthritis using differential network analysis of human synovial fluid
<p><strong>SS-218412_v4.1_other.hybNorm.medNormInt.plateScale.medNormSMP.adat</strong></p> <p>Main raw data file - normalized aptamer abundances</p> <p><strong>m4.L1_0.1_L2_0.001_ITER_10K_STABILITYSS_1K.rds</strong></p> <p>R data file object - GGM model output used in manuscript</p>
Effect of Probenecid on Synovial Fluid ATP Levels in CPPD
ClinicalTrials.gov study NCT02243631. IPD Sharing: NO. Countries: 1. Publications: 0.
Nociceptin Concentration in Synovial Fluid and Plasma
ClinicalTrials.gov study NCT02528916. IPD Sharing: Not stated. Countries: 0. Publications: 4.
To Look at the Characteristics of Synovial Fluid and Cartilage Matrix in Osteoarthritic Knee After Hyaluronic Acid Injection
ClinicalTrials.gov study NCT01895959. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Single-cell transcriptomes and T cell receptor sequences of memory T lymphocytes from the peripheral blood and the synovial fluid of patients with juvenile idiopathic arthritis.
GEO Series GSE160097. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
RNAseq analysis of peripheral blood and synovial fluid neutrophils from rheumatoid arthritis patients
GEO Series GSE154474. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics profiling of CD141+ dendritic cells isolated from peripheral blood or synovial fluid of arthritis patients
GEO Series GSE108174. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA-seq of CD8 T cells sorted from one sample of seropositive rheumatoid arthritis synovial fluid
GEO Series GSE202366. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Characterization of extracellular vesicles in plasma and synovial fluid of horses with naturally occurring post-traumatic osteoarthritis: An exploratory study to identify transcriptomic profiles.
GEO Series GSE256340. Equus caballus. 4 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Single cell RNA and TCR sequencing reveals substantive similarities between synovial fluid and synovial tissue T-cells in inflammatory arthritis.
GEO Series GSE250242. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Bulk RNA-seq of human synovial fluid CD8 T cells sorted by Granzyme B vs Granzyme K expression
GEO Series GSE202365. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Extracellular vesicle microRNA profiling in synovial fluids and plasma from Oligoarticular Juvenile Idiopathic Arthritis patients: methodological challenges and identification of putative disease biom
GEO Series GSE191326. Homo sapiens. 24 samples. Type: Expression profiling by RT-PCR.
RNA-seq analysis of IL-17A+/IFNy+ CD8+ and IL-17A+CD4+ T cells from Psoriatic Arthritis Synovial Fluid
GEO Series GSE137510. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional effects of LXR on the differentiation of monocyte-derived macrophages by tumor ascitic fluids or rheumatoid arthritis synovial fluids
GEO Series GSE181313. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.