Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
41
datasets available to search
ShareScore release 0.9.0
Dataset results
41 results for “TSH”
Phenanthrene: TD-DFTB datasets, pre-trained SchNet models and initial coniditions for TSH
<p><em>Data associated with the paper entitled </em></p> <p><strong>On application of Deep Learning to simplified quantum-classical dynamics in electronically excited states</strong></p> <ol> <li>Three TD-DFTB datasets (<strong>sX_10_force.db</strong>) have been produced using the <a href="https://wiki.fysik.dtu.dk/ase/">Atomic Simulation Environment</a> (ASE) coupled to <a href="http://demon-nano.ups-tlse.fr/">deMon-Nano</a> code for the linear response Time-Dependent Density Functional based Tight-Binding (TD-DFTB) calculations. Each dataset contains 10000 TD-DFTB electronic structure calculations for a given excited singlet state (S<sub>2</sub>/S<sub>3</sub>/S<sub>4</sub>) of a neutral phenanthrene molecule. Each database entry contains Cartesian atomic coordinates as well as potential energy and atomic forces for a given excited state at a given geometry. Since ASE has been used, all physical quantities are stored in the corresponding units (e.g. eV for energy or eV/Å for forces). The file format is SQLite as provided by the ASE;</li> <li>Three pre-trained Deep Learning models (<strong>best_model_sX</strong>) for a given excited singlet state have been produced using <a href="https://schnetpack.readthedocs.io/en/stable/">SchNetPack</a> package, which implements the SchNet architecture for atomistic simulations. Each model has been trained using the corresponding TD-DFTB dataset from #1. The file format is binary as provided by the SchNetPack;</li> <li><a href="https://zenodo.org/api/files/f1925cb5-66a8-4c6f-809b-3414f0cbc1d5/500_init_conditions.tar.gz"><strong>500_init_conditions.tar.gz</strong> </a> contains 500 initial conditions (Cartesian coordinates and velocities), which can be used for Trajectory Surface Hopping (TSH) simulations with or without the pre-trained models from #2.</li> </ol> <p> </p>
Data from: Computational model of the full-length TSH receptor
<p>The receptor for thyroid stimulating hormone (TSHR), a GPCR, is of particular interest as the primary antigen in autoimmune hyperthyroidism (Graves' disease) caused by stimulating TSHR antibodies. To date, only one domain of the extracellular region of the TSHR has been crystallized. We have run a 1000ns Molecular Dynamic simulation on a model of the entire TSHR generated by merging the extracellular region of the receptor, obtained using artificial intelligence, with our recent homology model of the transmembrane domain, embedded it in a lipid membrane solvated it with water and counterions. The simulations showed that the structure of the transmembrane and leucine-rich domains were remarkably constant while the linking region (LR), known more commonly as the "hinge region", showed significant flexibility, forming several transient secondary structural elements. Furthermore, the relative orientation of the leucine-rich domain with the rest of the receptor was also seen to be variable. These data suggest that this linker region is an intrinsically disordered protein (IDP). Furthermore, preliminary data simulating the full TSHR model complexed with its ligand (TSH) showed that (a) there is a strong affinity between the linker region and TSH ligand and (b) the association of the linker region and the TSH ligand reduces the structural fluctuations in the linker region. This full-length model illustrates the importance of the linker region in responding to ligand binding and lays the foundation for studies of pathologic TSHR autoantibodies complexed with the TSHR to give further insight into their interaction with the flexible linker region.</p> <p>The dataset represents the coordinates of a model of the Thyroid Stimulating Hormone Recpetor (TSHR) built from the AI-based alphafold2 model of the TSHR ectodomain and the MD geverated model of the transmembrane domain (TMD) of TSHR.</p>
Study to Verify Clinical Utility of Point-of-Care (POC) Thyroid Stimulating Hormone (TSH) Test Kits as Compared to Third Generation TSH Test Kit
ClinicalTrials.gov study NCT01921452. IPD Sharing: Not stated. Countries: 1. Publications: 1.
TSH Risk by Extraction Site in Lap Cholecystectomy
ClinicalTrials.gov study NCT06953713. IPD Sharing: YES. Countries: 1. Publications: 1.
Data from: Computational model of the full-length TSH receptor
Open the record for dataset details and reuse information.
TSH vs SEMEN PARAMETERS
<p>A dataset of 130 men who were evaluated for couple subfertility. The dataset includes Age, BMI, TSH, semen volume, semen concentration, total sperm count. </p>
Supplementary files:TSH Promotes Right Ventricle Energy Metabolism Remodeling and Hypertrophy
Open the record for dataset details and reuse information.
SUSTAINED PITUITARY T3 PRODUCTION EXPLAINS THE T4-MEDIATED TSH FEEDBACK MECHANISM
<p>Supplemental data for the manuscript "Sustained pituitary T3 production explains the T4-mediated TSH feedback"</p>
TSH Suppression During Radiotherapy on Thyroid Site to Prevent Iatrogenic Hypothyroidism in Pediatric Cancer Patients
ClinicalTrials.gov study NCT05316922. IPD Sharing: NO. Countries: 1. Publications: 6.
Normal Range of TSH and FT4 in Pregnancy
ClinicalTrials.gov study NCT04860622. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Interrelations Between FT3, FT4 and Pituitary TSH
ClinicalTrials.gov study NCT01969552. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Upper Limit for TSH of First and Second Trimester Pregnancy in Turkey
ClinicalTrials.gov study NCT03754621. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
TSH Receptor Mutations Among a Consanguineous Community
ClinicalTrials.gov study NCT00747760. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Correlation Between Levothyroxine and Blood Th17/Treg in Pregnant Women With Normal-high TSH and Positive TPOAb
ClinicalTrials.gov study NCT06527859. IPD Sharing: NO. Countries: 1. Publications: 17.
Supplemental Table and Figures for TSH Trajectories in the ELSA-Brasil Cohort
Open the record for dataset details and reuse information.
Correlation Between TCM Syndrome Factors and TSH Changes of Thyroid Hormone Withdrawal Before Iodine Therapy in Postoperative Patients With Thyroid Cancer
ClinicalTrials.gov study NCT04916262. IPD Sharing: Not stated. Countries: 0. Publications: 4.
Desiccated Thyroid Extract Combined With Levothyroxine for TSH Suppression Therapy in DTC
ClinicalTrials.gov study NCT07239674. IPD Sharing: UNDECIDED. Countries: 0. Publications: 9.
Thyroid Stimulating Hormone (TSH) Level Variations in Early Pregnancy
ClinicalTrials.gov study NCT04565873. IPD Sharing: NO. Countries: 1. Publications: 0.
Comparison of Iodine-124 (I-124) and Iodine-131 (I-131) Radiopharmacokinetics in Patients Prepared With Recombinant Human TSH Injection (rhTSH)
ClinicalTrials.gov study NCT00926978. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluating a Our Practice Advisory (OPA) to Optimize Hemoglobin A1c (A1c) and Thyroid-Stimulating Hormone (TSH) Test Orders
ClinicalTrials.gov study NCT06993805. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.