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3 results for “Takifugu obscurus”
Data from: Effects of 9,10-phenanthrenequione on antioxidant indices and metabolite profiles in Takifugu obscurus plasma
<p class="MDPI31text"><span><span>Derived from polycyclic aromatic hydrocarbons (PAHs), oxygenated-PAHs (oxy-PAHs) may pose hazards to </span></span><span><span>aquatic</span></span><span><span> organisms, which remains largely unknown</span></span>. <i><span><span>Takifugu obscurus</span></span></i><span><span> is an important anadromous fish species </span></span><span><span>of </span></span><span><span>high economic and ecological values. </span></span><span><span>In </span></span><span><span>t</span></span><span><span>he present study,</span></span><span><span> <i>T. obscurus</i> </span></span><span><span>was</span></span><span><span> acutely exposed to</span></span> <span><span>44.29 </span></span><span><span>μg/L</span></span><span><span> 9,10-phenanthrenequione (9,10-PQ) for 96 hours. </span></span><span><span>Change</span></span><span><span>s of antioxidant indices and metabolite profiles in plasma were compared between 9,10-PQ treatment and the control. The results showed that 9,10-PQ treatment significantly increased MDA content during 6 hours to 96 hours, increased SOD and CAT activities at 6 hours, but decreased them at 96 hours. These results indicated that 9,10-PQ induced oxidative stress to fish. </span></span><span><span>Ultra-performance liquid chromatography-mass spectrometry (UPLC-MS)</span></span><span><span> analysis revealed that four</span></span><span><span> metabolic pathways were influenced in response </span></span><span><span>to treatment with 9,10-PQ, including </span></span><span><span>glycerophospholipid metabolism</span></span><span><span>,</span></span><span><span> phenylalanine, tyrosine and tryptophan biosynthesis</span></span><span><span>,</span></span><span><span> purine metabolism and sulfur metabolism. These pathways </span></span><span>are </span><span>associated with </span><span>antioxidant mechanisms, biosynthesis of </span><span>neurotransmitters and innate immune functions. Thus, the as-obtained results confirmed that 9,10-PQ induced</span> oxidative stress and raised concerns of neurotoxicity and immunotoxicity to fish. <span>Overall, the present study posed a high environmental risk of oxy-PAHs to aquatic ecosystems. </span><span><span>Derived from polycyclic aromatic hydrocarbons (PAHs), oxygenated-PAHs (oxy-PAHs) may pose hazards to </span></span><span><span>aquatic</span></span><span><span> organisms, which remains largely unknown</span></span>. <i><span><span>Takifugu obscurus</span></span></i><span><span> is an important anadromous fish species </span></span><span><span>of </span></span><span><span>high economic and ecological values. </span></span><span><span>In </span></span><span><span>t</span></span><span><span>he present study,</span></span><span><span> <i>T. obscurus</i> </span></span><span><span>was</span></span><span><span> acutely exposed to</span></span> <span><span>44.29 </span></span><span><span>μg/L</span></span><span><span> 9,10-phenanthrenequione (9,10-PQ) for 96 hours. </span></span><span><span>Change</span></span><span><span>s of antioxidant indices and metabolite profiles in plasma were compared between 9,10-PQ treatment and the control. The results showed that 9,10-PQ treatment significantly increased MDA content during 6 hours to 96 hours, increased SOD and CAT activities at 6 hours, but decreased them at 96 hours. These results indicated that 9,10-PQ induced oxidative stress to fish. </span></span><span><span>Ultra-performance liquid chromatography-mass spectrometry (UPLC-MS)</span></span><span><span> analysis revealed that four</span></span><span><span> metabolic pathways were influenced in response </span></span><span><span>to treatment with 9,10-PQ, including </span></span><span><span>glycerophospholipid metabolism</span></span><span><span>,</span></span><span><span> phenylalanine, tyrosine and tryptophan biosynthesis</span></span><span><span>,</span></span><span><span> purine metabolism and sulfur metabolism. These pathways </span></span><span>are </span><span>associated with </span><span>antioxidant mechanisms, biosynthesis of </span><span>neurotransmitters and innate immune functions. Thus, the as-obtained results confirmed that 9,10-PQ induced</span> oxidative stress and raised concerns of neurotoxicity and immunotoxicity to fish. <span>Overall, the present study posed a high environmental risk of oxy-PAHs to aquatic ecosystems. </span></p>
Data from: Effects of 9,10-phenanthrenequione on antioxidant indices and metabolite profiles in Takifugu obscurus plasma
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Transcriptome analysis of the kidney of obscure puffer Takifugu obscurus challenged with poly(I:C)
GEO Series GSE181941. Takifugu obscurus. 9 samples. Type: Expression profiling by high throughput sequencing.
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