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54 results for “Thoracic aneurysms.”
Raw Data for the article: Patient-Specific Analysis of Ascending Thoracic Aortic Aneurysm with the Living Heart Human Model
<p>In ascending thoracic aortic aneurysms (ATAAs), aneurysm kinematics are driven by ventricular traction occurring every heartbeat, increasing the stress level of dilated aortic wall. Aortic elongation due to heart motion and aortic length are emerging as potential indicators of adverse events in ATAAs; however, simulation of ATAA that takes into account the cardiac mechanics is technically challenging. The objective of this study was to adapt the realistic Living Heart Human Model (LHHM) to the anatomy and physiology of a patient with ATAA to assess the role of cardiac motion on aortic wall stress distribution. Patient-specific segmentation and material parameter estimation were done using preoperative computed tomography angiography (CTA) and ex vivo biaxial testing of the harvested tissue collected during surgery. The lumped-parameter model of systemic circulation implemented in the LHHM was refined using clinical and echocardiographic data. The results showed that the longitudinal stress was highest in the major curvature of the aneurysm, with specific aortic quadrants having stress levels change from tensile to compressive in a transmural direction. This study revealed the key role of heart motion that stretches the aortic root and increases ATAA wall tension. The ATAA LHHM is a realistic cardiovascular platform where patient-specific information can be easily integrated to assess the aneurysm biomechanics and potentially support the clinical management of patients with ATAAs.</p>
Thoracic Endoprosthesis for Treatment of Aneurysm of the Descending Thoracic Aortic
ClinicalTrials.gov study NCT00874250. IPD Sharing: NO. Countries: 1. Publications: 2.
Study of GSK1278863 to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm Repair
ClinicalTrials.gov study NCT01920594. IPD Sharing: Not stated. Countries: 2. Publications: 1.
STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft
ClinicalTrials.gov study NCT00111176. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Fibroblasts and Thoracic Aortic Aneurysms: in Vitro Characterization in With Marfan Syndrome and Genetic Aortic Diseases
ClinicalTrials.gov study NCT06786754. IPD Sharing: NO. Countries: 1. Publications: 3.
RelayPro Thoracic Stent-Graft in Subjects With Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers
ClinicalTrials.gov study NCT02818972. IPD Sharing: NO. Countries: 2. Publications: 1.
The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure
ClinicalTrials.gov study NCT00110201. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Clinical Study on the Prevention of Surgical Wound Complications for Aneurysmal Thoracic-abdominal Aortic Pathology Using the "PREVENA" System
ClinicalTrials.gov study NCT03512470. IPD Sharing: NO. Countries: 1. Publications: 3.
Fibroblast Line Evaluation for COL5A eXpression and Thoracic Aortic Aneurysms: in Vitro Characterization of Cutaneous Fibroblasts in Adult Patients
ClinicalTrials.gov study NCT07282717. IPD Sharing: NO. Countries: 1. Publications: 3.
MITAORTA - Role of Mitochondrial Dynamic in Aneurysm and Dissection of Ascending Thoracic Aorta
ClinicalTrials.gov study NCT05434481. IPD Sharing: NO. Countries: 1. Publications: 6.
Effects of Exercise on Thoracic Aneurysms
ClinicalTrials.gov study NCT04197648. IPD Sharing: NO. Countries: 1. Publications: 4.
Clinical Study of Thoracic Aortic Aneurysm Exclusion
ClinicalTrials.gov study NCT00549315. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance
ClinicalTrials.gov study NCT03536312. IPD Sharing: NO. Countries: 2. Publications: 1.
Is Obstructive Sleep Apnoea a Risk Factor for Thoracic Aortic Aneurysm Expansion? A Prospective Cohort Study.
ClinicalTrials.gov study NCT02204774. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effective Treatments for Thoracic Aortic Aneurysms (ETTAA Study): A Prospective Cohort Study
ClinicalTrials.gov study NCT02010892. IPD Sharing: Not stated. Countries: 1. Publications: 1.
National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions
ClinicalTrials.gov study NCT01322165. IPD Sharing: Not stated. Countries: 1. Publications: 22.
Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Thoracal Abdominal Aneurysms
ClinicalTrials.gov study NCT01354821. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Feasibility Study for GORE® TAG® Thoracic Branch Endoprosthesis to Treat Proximal Descending Thoracic Aortic Aneurysms
ClinicalTrials.gov study NCT02021812. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of the GORE TAG Thoracic Endoprosthesis in the Treatment of Aneurysms
ClinicalTrials.gov study NCT00590759. IPD Sharing: Not stated. Countries: 1. Publications: 0.
GORE TAG® Thoracic Endoprosthesis - 45 mm for the Treatment of Aneurysms of the Descending Thoracic Aorta
ClinicalTrials.gov study NCT00608829. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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