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ShareScore release 0.9.0
Dataset results
163 results for “Tissue repair.”
Data from: Bony lesions in early tetrapods and the evolution of mineralized tissue repair
Bone healing is an important survival mechanism, allowing vertebrates to recover from injury and disease. Here we describe newly recognized paleopathologies in the hindlimbs of the early tetrapods Crassigyrinus scoticus and Eoherpeton watsoni from the Early Carboniferous of Cowdenbeath, Scotland. These pathologies are among the oldest known instances of bone healing in tetrapod limb bones in the fossil record (about 325 Myr old). X-ray microtomographic imaging of the internal bone structure of these lesions shows that they are characterized by a mass of trabecular bone separated from the shaft's trabeculae by a layer of cortical bone. We frame these paleopathologies in an evolutionary context, including additional data on bone healing and its pathways across extinct and extant sarcopterygians. These data allowed us to synthesize information on cell-mediated repair of bone and other mineralized tissues in all vertebrates, to reconstruct the evolutionary history of skeletal tissue repair mechanisms. We conclude that bone healing is ancestral for sarcopterygians. Furthermore, other mineralized tissues (aspidin and dentine) were also capable of healing and remodeling early in vertebrate evolution, suggesting that these repair mechanisms are synapomorphies of vertebrate mineralized tissues. The evidence for remodeling and healing in all of these tissues appears concurrently, so in addition to healing these early vertebrates had the capacity to restore structure and strength by remodeling their skeleton. Healing appears to be an inherent property of these mineralized tissues, and its linkage to their remodeling capacity has previously been under-appreciated.
Vascular Damage and Repair - Are Small-diameter Vascular Grafts Still the "Holy Grail" of Tissue Engineering?
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Treatment of Alveolar Bone Defects Using Aastrom Biosciences Autologous Tissue Repair Cell Therapy
ClinicalTrials.gov study NCT00755911. IPD Sharing: Not stated. Countries: 1. Publications: 44.
Musculotendinous Tissue Repair Unit and Reinforcement (MTURR)
ClinicalTrials.gov study NCT01292876. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Repair of Soft Tissue Defect of the Finger Using the Heterodigital Neurocutaneous Island Flap
ClinicalTrials.gov study NCT01778296. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Bone Tissue Engineering Using Autologous Bone Repair Cell (BRC) Therapy for Sinus Floor Bone Augmentation
ClinicalTrials.gov study NCT00980278. IPD Sharing: Not stated. Countries: 1. Publications: 12.
The SERI® Surgical Scaffold Use in Reconstruction Post Market Study for Tissue Support and Repair in Breast Reconstruction Surgery
ClinicalTrials.gov study NCT01256502. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Absorbable Suture Versus Tissue Glue to Repair Defects Following Mohs Surgery
ClinicalTrials.gov study NCT01298167. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Bony lesions in early tetrapods and the evolution of mineralized tissue repair
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Data from: Tissue-specific mutagenesis from endogenous guanine damage is suppressed by PolK and DNA repair
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Randomized Study of Anular Repair With the Xclose Tissue Repair System
ClinicalTrials.gov study NCT00760799. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Gene-activated Matrix for Bone Tissue Repair in Maxillofacial Surgery
ClinicalTrials.gov study NCT02293031. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Prospective Clinical Observational Cohort Study to Evaluate the Use of a Tissue Separating Mesh (Proceed®) in Laparoscopic Ventral Hernia Repair
ClinicalTrials.gov study NCT00572962. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Bone Tissue Engineering With Dental Pulp Stem Cells for Alveolar Cleft Repair
ClinicalTrials.gov study NCT03766217. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Action of Photodynamic Therapy on Wound Quality and Tissue Repair in the Diabetic Foot
ClinicalTrials.gov study NCT06416462. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Traditional Vaginal Surgery VS Autologous Tissue in Pelvic Floor Repair
ClinicalTrials.gov study NCT05628831. IPD Sharing: YES. Countries: 1. Publications: 9.
Effect of Cell Surface Markers and Lymphoid Cell Distribution on the Arterial Tissue Repair (ECLAR)
ClinicalTrials.gov study NCT02421081. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Musculotendinous Tissue Unit Repair and Reinforcement (MTURR) Coordinating Center
ClinicalTrials.gov study NCT01497678. IPD Sharing: Not stated. Countries: 1. Publications: 9.
EktoTherix™ Regenerative Tissue Scaffold for Repair of Surgical Excision Wounds
ClinicalTrials.gov study NCT02409628. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Restorelle® Mesh Versus Native Tissue Repair for Prolapse
ClinicalTrials.gov study NCT02162615. IPD Sharing: Not stated. Countries: 6. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.