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Histological Dataset for Microvascular Segmentation of Tissue-Engineered Vascular Grafts
<p><strong>Objectives: </strong>The pursuit of understanding vascular tissue regeneration within tissue-engineered vascular grafts (TEVGs) is of paramount importance due to the critical role these grafts play in replacing damaged or diseased blood vessels. TEVGs offer a promising alternative to traditional grafts, with the potential to integrate into the host's tissue and support the natural regenerative processes. However, challenges such as thrombosis, inflammation, and the need for grafts that can adapt to the dynamic biological environment remain. By studying the regenerative processes in TEVGs, researchers can gain insights into the mechanisms that underpin successful graft integration and function, which is essential for improving patient outcomes in vascular surgeries. This dataset, with its detailed annotations of histological features, provides a valuable resource for developing and refining machine-learning models that can analyze and predict patterns of vascular tissue regeneration. The ability to accurately segment and quantify microvessels and immune cells in regenerated arteries is a significant step forward in distinguishing between physiological and pathological regeneration, ultimately contributing to the design of more effective and reliable TEVGs for clinical use.</p> <p><strong>Ethical Approval: </strong>Experimental strategy of the study is described in detail in <a href="https://www.mdpi.com/2073-4360/14/23/5149" target="_blank" rel="noopener">[1]</a> and <a href="https://www.mdpi.com/1422-0067/24/10/8540" target="_blank" rel="noopener">[2]</a>. The study was conducted according to the guidelines of the Declaration of Helsinki, and was approved by the Local Ethical Committee of the Research Institute for Complex Issues of Cardiovascular Diseases (Kemerovo, Russia, protocol code 2020/06, date of approval: 19 February 2020). Animal experiments were performed in accordance with the European Convention for the Protection of Vertebrate Animals (Strasbourg, 1986) and Directive 2010/63/EU of the European Parliament on the protection of animals used for scientific purposes. For the implantation, we used female Edilbay sheep of 42–45 kg body weight which were received from the Animal Core Facility of the Research Institute for Complex Issues of Cardiovascular Diseases (Kemerovo, Russia) and selected for the surgery by Doppler ultrasonography to identify those having carotid artery diameter of 4.0 ± 0.2 mm.</p> <p><strong>Description: </strong>The dataset comprises a collection of Whole Slide Images (WSIs) obtained from biodegradable TEVGs implanted into the carotid arteries of 20 sheep. A total of 104 WSIs were acquired, each measuring an average size of 135,000 x 123,000 pixels. These WSIs were stained using Hematoxylin and Eosin (H&E), a common practice for highlighting the structure of tissue sections, which facilitates the detailed examination of histological features. These WSIs were automatically sliced into 99,831 patches of 3,000 x 3,000 pixels and subsequently filtered, resulting in 1,401 selected patches for manual annotation.</p> <p><strong>Annotation Method:</strong> Two pathologists independently selected and meticulously annotated the 1401 patches, identifying nine distinct histological features associated with vascular tissue regeneration. These features include <em>arteriole lumen (AL)</em>, <em>arteriole media (AM)</em>, <em>arteriole adventitia (AA)</em>, <em>venule lumen (VL)</em>, <em>venule wall (VW)</em>, <em>capillary lumen (CL)</em>, <em>capillary wall (CW)</em>, <em>immune cells (IC)</em>, and <em>nerve trunks (NT)</em>. The annotations were performed using binary masks, delineating each feature within the patches. Subsequently, a senior pathologist conducted a triple verification process, reviewing and refining the annotations to ensure accuracy and consistency. The annotations are provided in the form of binary masks, meticulously defined for each feature within the patches.</p> <p><strong>Dataset Split:</strong> Given the limited number of subjects studied, comprising 20 sheep, we employed a 5-fold cross-validation technique to split our dataset. This method was chosen because it allows for the efficient use of limited data, ensuring that each observation has the opportunity to be used in both the training and testing sets, thus reducing bias and providing a more accurate estimate of the model's performance. In this approach, each fold involved 16 sheep for training and the remaining 4 for testing (see <em>Table 1</em> and <em>Figure 3</em>). This partitioning scheme was consistently applied to maintain the integrity of subject groups within each subset and to prevent data leakage. The 5-fold cross-validation is particularly beneficial for our study's objectives as it maximizes the training data available for developing robust machine learning models while also ensuring that the models are tested on unseen data, thereby enhancing the generalizability of our findings.</p> <p><strong>Access to the Study:</strong> Further information about this study, including curated source code, dataset details, and trained models, can be accessed through the following repositories:</p> <ul> <li><strong>Source code:</strong> <a href="https://github.com/ViacheslavDanilov/histology_segmentation" target="_blank" rel="noopener">https://github.com/ViacheslavDanilov/histology_segmentation</a></li> <li><strong>Dataset:</strong> <a href="https://doi.org/10.5281/zenodo.10838384" target="_blank" rel="noopener">https://doi.org/10.5281/zenodo.10838384</a></li> <li><strong>Models:</strong> <a href="https://doi.org/10.5281/zenodo.10838431" target="_blank" rel="noopener">https://doi.org/10.5281/zenodo.10838431</a></li> </ul> <div> </div> <div><em><strong>Table 1.</strong> Patch and feature distributions across folds and subsets</em> <table> <tbody> <tr> <td> <p><strong>Fold</strong></p> </td> <td> <p><strong>Subset</strong></p> </td> <td> <p><strong>Patches</strong></p> </td> <td> <p><strong>AL</strong></p> </td> <td> <p><strong>AM</strong></p> </td> <td> <p><strong>AA</strong></p> </td> <td> <p><strong>VL</strong></p> </td> <td> <p><strong>VW</strong></p> </td> <td> <p><strong>CL</strong></p> </td> <td> <p><strong>CW</strong></p> </td> <td> <p><strong>IC</strong></p> </td> <td> <p><strong>NT</strong></p> </td> <td> <p><strong>Total </strong></p> </td> </tr> <tr> <td> <p>1</p> </td> <td> <p>Train</p> </td> <td> <p>1168</p> </td> <td> <p>510</p> </td> <td> <p>512</p> </td> <td> <p>220</p> </td> <td> <p>675</p> </td> <td> <p>648</p> </td> <td> <p>770</p> </td> <td> <p>765</p> </td> <td> <p>409</p> </td> <td> <p>448</p> </td> <td> <p>4957</p> </td> </tr> <tr> <td>1</td> <td> <p>Test</p> </td> <td> <p>233</p> </td> <td> <p>81</p> </td> <td> <p>84</p> </td> <td> <p>36</p> </td> <td> <p>186</p> </td> <td> <p>169</p> </td> <td> <p>178</p> </td> <td> <p>182</p> </td> <td> <p>91</p> </td> <td> <p>25</p> </td> <td> <p>1032</p> </td> </tr> <tr> <td> <p>2</p> </td> <td> <p>Train</p> </td> <td> <p>1053</p> </td> <td> <p>406</p> </td> <td> <p>411</p> </td> <td> <p>179</p> </td> <td> <p>678</p> </td> <td> <p>638</p> </td> <td> <p>743</p> </td> <td> <p>746</p> </td> <td> <p>423</p> </td> <td> <p>315</p> </td> <td> <p>4539</p> </td> </tr> <tr> <td>2</td> <td> <p>Test</p> </td> <td> <p>348</p> </td> <td> <p>185</p> </td> <td> <p>185</p> </td> <td> <p>77</p> </td> <td> <p>183</p> </td> <td> <p>179</p> </td> <td> <p>205</p> </td> <td> <p>201</p> </td> <td> <p>77</p> </td> <td> <p>158</p> </td> <td> <p>1450</p> </td> </tr> <tr> <td> <p>3</p> </td> <td> <p>Train</p> </td> <td> <p>1127</p> </td> <td> <p>507</p> </td> <td> <p>511</p> </td> <td> <p>222</p> </td> <td> <p>743</p> </td> <td> <p>702</p> </td> <td> <p>759</p> </td> <td> <p>760</p> </td> <td> <p>299</p> </td> <td> <p>423</p> </td> <td> <p>4926</p> </td> </tr> <tr> <td>3</td> <td> <p>Test</p> </td> <td> <p>274</p> </td> <td> <p>84</p> </td> <td> <p>85</p> </td> <td> <p>34</p> </td> <td> <p>118</p> </td> <td> <p>115</p> </td> <td> <p>189</p> </td> <td> <p>187</p> </td> <td> <p>201</p> </td> <td> <p>50</p> </td> <td> <p>1063</p> </td> </tr> <tr> <td> <p>4</p> </td> <td> <p>Train</p> </td> <td> <p>1064</p> </td> <td> <p>466</p> </td> <td> <p>472</p> </td> <td> <p>199</p> </td> <td> <p>611</p> </td> <td> <p>566</p> </td> <td> <p>759</p> </td> <td> <p>758</p> </td> <td> <p>423</p> </td> <td> <p>291</p> </td> <td> <p>4545</p> </td> </tr> <tr> <td>4</td> <td> <p>Test</p> </td> <td> <p>337</p> </td> <td> <p>125</p> </td> <td> <p>124</p> </td> <td> <p>57</p> </td> <td> <p>250</p> </td> <td> <p>251</p> </td> <td> <p>189</p> </td> <td> <p>189</p> </td> <td> <p>77</p> </td> <td> <p>182</p> </td> <td> <p>1444</p> </td> </tr> <tr> <td> <p>5</p> </td> <td> <p>Train</p> </td> <td> <p>1192</p> </td> <td> <p>475</p> </td> <td> <p>478</p> </td> <td> <p>204</p> </td> <td> <p>737</p> </td> <td> <p>714</p> </td> <td> <p>761</p> </td> <td> <p>759</p> </td> <td> <p>446</p> </td> <td> <p>415</p> </td> <td> <p>4989</p> </td> </tr> <tr> <td>5</td> <td> <p>Test</p> </td> <td> <p>209</p> </td> <td> <p>116</p> </td> <td> <p>118</p> </td> <td> <p>52</p> </td> <td> <p>124</p> </td> <td> <p>103</p> </td> <td> <p>187</p> </td> <td> <p>188</p> </td> <td> <p>54</p> </td> <td> <p>58</p> </td> <td> <p>1000</p> </td> </tr> </tbody> </table> </div> <p> </p>
Klf14 mouse white adipose tissue histology DeepZoom files and AIDA annotations for visualisation of DeepCytometer white adipocyte segmentations
<p>Latest description of this data set: <a href="https://github.com/MRC-Harwell/cytometer/blob/main/DATA.md">Data.md at cytometer project</a></p> <pre># Publications related to the data The data associated to the DeepCytometer project (https://github.com/MRC-Harwell/cytometer) is available from Zenodo (doi: 10.5281/zenodo.5137433 and 10.5281/zenodo.5149005). The histology and mouse measures were generated as part of the Small et al. 2018 study: > Small et al. "Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition". Nature Genetics, 50:572–580, 2018. The hand traced data set, colour maps, and automatic segmentations were generated for the Casero et al. 2021 paper: > Casero et al. "Phenotyping of Klf14 mouse white adipose tissue enabled by whole slide segmentation with deep neural networks". bioRxiv, 2021. doi: [10.1101/2021.06.03.444997](https://www.biorxiv.org/content/10.1101/2021.06.03.444997v1.full). # Data protocols ## Histology and laboratory measures To develop and evaluate our methods we used Klf14tm1(KOMP)Vlcg C57BL/6NTac (B6NTac) mice tissue samples and additional data generated as part of the Small et al. 2018 study(Small et al. 2018). It should be noted that the single exon Klf14 gene is imprinted and only expressed from the maternally inherited allele(Parker-Katiraee et al. 2007). This was taken into account by (Small et al. 2018) by crossing a Het parent with a WT parent, so that each offspring inherited a WT allele from the WT parent, and the Klf14 gene knockout or a WT allele from the other parent (from the father, PAT, or the mother, MAT). We also take Klf14 imprinting into account by using as controls the PAT mice and comparing them to the MAT WT and MAT Het (or functional KO, FKO) mice. We used a total of 76 Klf14-B6NTac mice (nfemale=nmale=38), of which 20 mice from the Control and FKO groups were used for training and testing the DeepCytometer pipeline, as well as the hand traced population experiment (summary in Table MICE). The histopathology screen involved fixing, processing and embedding in wax, sectioning and staining with Hematoxylin and Eosin (H&E) both inguinal subcutaneous and gonadal adipose depots. For paraffin-embedded sections, all samples were fixed in 10% neutral buffered formalin (Surgipath) for at least 48 hours at RT and processed using an Excelsior™ AS Tissue Processor (Thermo Scientific). Samples were embedded in molten paraffin wax and 8 μm sections were cut through the respective depots using a Finesse™ ME+ microtome (Thermo Scientific). Sampling was conducted at 2sxns per slide, 3 slides per depot block onto simultaneous charged slides, stained with haematoxylin Gill 3 and eosin (Thermo scientific) and scanned using an NDP NanoZoomer Digital pathology scanner (RS C10730 Series; Hamamatsu). Body weight (BW) and depot weight (DW) were measured with Satorius BAL7000 scales. ## White adipose tissue segmentation For cell area quantification, we applied DeepCytometer v8 to 75 inguinal subcutaneous and 72 gonadal whole histology slides with DeepCytometer (with the Corrected method), including the 20 slides sampled for the hand-traced data set, corresponding to 73 females and 74 males, to produce 2,560,067 subcutaneous and 2,467,686 gonadal cells (on average, 34,134 and 34,273 cells per slide, respectively). Full segmentation of all whole slides was performed with script [klf14_b6ntac_exp_0106_full_slide_pipeline_v8.py](https://github.com/MRC-Harwell/cytometer/blob/39358ed1d79df07d1d522b98728c7efd745513f7/scripts/klf14_b6ntac_exp_0106_full_slide_pipeline_v8.py). In this case, the segmentation contours were grouped by tiles in the output AIDA annotation `.json` file (one contour per cell, one file per slide). Non-white adipocyte contours were filtered out, and white adipocyte contours were aggregated into an AIDA annotation `.json` file with a single tile with script [klf14_b6ntac_exp_0106_annotations_postprocessing_v8.py](https://github.com/MRC-Harwell/cytometer/blob/39358ed1d79df07d1d522b98728c7efd745513f7/scripts/klf14_b6ntac_exp_0106_annotations_postprocessing_v8.py) (one contour per cell, one file per slide). # List of directories and files ## Casero et al. (2021) "DeepCytometer pipeline parameter files, Klf14 mouse white adipose tissue histology and hand-traced training contours" (doi: 10.5281/zenodo.5137433) ### `deepcytometer_pipeline_v8.zip` (60.6 MB) Weights, colourmaps, etc. necessary to run the pipeline (v8, with mode colour correction). This is the version of the pipeline described in the paper. There are 10 weight files per convolutional neural network (CNN), corresponding to 10-fold cross-validation * `klf14_b6ntac_exp_0086_cnn_dmap_model_fold_[0..9].h5`: Keras weights for the **EDT CNN** (Histology to Euclidean Distance Transform regression) * `klf14_b6ntac_exp_0089_cnn_segmentation_correction_overlapping_scaled_contours_model_fold_[0..9].h5`: Keras weights for the **Correction CNN** (Segmentation Correction regression) * `klf14_b6ntac_exp_0091_cnn_contour_after_dmap_model_fold_[0..9].h5`: Keras weights for the **Contour CNN** (EDT to Contour detection) * `klf14_b6ntac_exp_0095_cnn_tissue_classifier_fcn_model_fold_[0..9].h5`: Keras weights for the **Tissue CNN** (Pixel-wise tissue classifier) * `klf14_b6ntac_exp_0094_generate_extra_training_images.pickle`: training dataset description * **'file_list'**: list of SVG files with hand-traced contours for network training. Each SVG file has a corresponding TIFF file with the histology used for segmentation * **'idx_test'**: 10 lists with file indices for testing in 10-fold cross-validation * **'idx_train'**: 10 lists with file indices for training in 10-fold cross-validation * **'fold_seed'**: seed number used for the random number generator to assign file indices to folds * `klf14_b6ntac_exp_0098_filename_area2quantile.npz`: quantile colour maps calculated in `klf14_b6ntac_exp_0098_full_slide_size_analysis_v7.py` using the whole Klf14 data set with v7 of the pipeline, and used in earlier experiments, including some where v8 of the pipeline was used for segmentation. * `klf14_b6ntac_exp_0106_filename_area2quantile_v8.npz`: quantile colour maps calculated in `klf14_b6ntac_exp_0106_full_slide_pipeline_v8.py` using the whole Klf14 data set with v8 of the pipeline, and used in later experiments. * `klf14_training_colour_histogram.npz`: statistics from Klf14 histology images to be used in colour correction * **'xbins_edge'**, **'xbins'**: edges and centres of the bins used for histogram calculations * **'hist_r_q1'**, **'hist_r_q2'**, **'hist_r_q3'** * **'hist_g_q1'**, **'hist_g_q2'**, **'hist_g_q3'** * **'hist_b_q1'**, **'hist_b_q2'**, **'hist_b_q3'**: density quartiles (Q1, Q2, Q3) for RGB channels for each bin the histogram * **'mode_r'**, **'mode_g'**, **'mode_b'**: modes for RGB channels (this corresponds to the most typical background colour in the histology images) * **'mean_l'**, **'mean_a'**, **'mean_b'**: mean intensity for L*a*b channels of the image * **'std_l'**, **'std_a'**, **'std_b'**: intensity standard deviations for L*a*b channels of the image * `klf14_exp_0112_training_colour_histogram.npz`: other statistics from Klf14 histology images to be used in colour correction * **'p'**: vector of quantile values used in ECDF calculations * **'val_r_klf14'**, **'val_g_klf14'**, **'val_b_klf14'**: all intensity values for the RGB channels of Klf14 training images that contain at least a white adipocyte * **'f_ecdf_to_val_r_klf14'**, **'f_ecdf_to_val_g_klf14'**, **'f_ecdf_to_val_b_klf14'**: linear interpolation function that maps ECDF quantiles to intensity values in the Klf14 training data set. These functions can be used together with intensity->quantile interpolation functions calculated for a new histology image to perform histogram matching colour correction * **'mean_klf14'**, **'std_klf14'**: mean and standard deviation of the **'val_r_klf14'**, **'val_g_klf14'**, **'val_b_klf14'** vectors There are also weight files for the pipeline trained with all the data, instead of the 10-fold cross-validation partition. These were not used for the paper, but could be useful for future experiments * `klf14_b6ntac_exp_0101_cnn_dmap_model.h5`: Keras weights for the **EDT CNN** (Histology to Euclidean Distance Transform regression) * `klf14_b6ntac_exp_0104_cnn_segmentation_correction_overlapping_scaled_contours_model.h5`: Keras weights for the **Correction CNN** (Segmentation Correction regression) * `klf14_b6ntac_exp_0102_cnn_contour_after_dmap_model.h5`: Keras weights for the **Contour CNN** (EDT to Contour detection) * `klf14_b6ntac_exp_0103_cnn_tissue_classifier_fcn_model.h5`: Keras weights for the **Tissue CNN** (Pixel-wise tissue classifier) ### `histology.7z` (29.1 GB) 165 H&E histology whole slides from Hamamatsu scanner (`.ndpi`). ### `klf14.7z` (2.3 GB) Mice metadata, training/testing data sets for the pipeline, intermediate files created during training, and neural network weights for multiple experiments. * `klf14_b6ntac_meta_info.csv`: Klf14 mice metadata * **Animal Identifier**, **id:** unique ID for each mouse * **ko_parent:** heterozygous parent of origin for the KO allele (father, PAT or mother, MAT) * **sex:** female or male * **genotype:** wild type (KLF14-KO:WT) or heterozygous (KLF14-KO:Het) * **BW:** body weight (g) * **SC:** subcutaneous depot weight (g) * **gWAT:** gonadal depot weight (g) * **Liver:** livel weight (g) * **cull_age:** age at time of culling (days) * **BW_alive:** body weight measured before culling * **BW_alive_date:** age at time of BW_alive measure * **mother:** unique ID for mouse's mother * **mother_genotype:** mouse's mother genotype * `klf14_b6ntac_training`: Directory with hand-traced segmentations of training histology windows. 131 windows sampled from 20 whole slides, plus hand-traced contours that were used for training DeepCytometer and compute population distributions. These segmentations were used for CNN training, but note that there's a cleaned-up version of these data below, and it was the cleaned-up version that was used for the paper experiments * `ndpifile_row_YYYYYY_col_XXXXXX[.tif/.xcf/.svg]`: * **ndpifile:** name of the whole slide file (e.g. `KLF14-B6NTAC 36.1c PAT 98-16 C1 - 2016-02-11 10.45.00`) * **row_YYYYYY:** Y-coordinate of the top-left corner of the sampling window, in pixels * **col_XXXXXX:** X-coordinate of the top-left corner of the sampling window, in pixels * **.tif:** TIFF file with the histology sampling window * **.xcf:** Gimp file with the histology and hand-traced contours (the contours were drawn in Gimp) * **.svg:** SVG (Scalable Vector Graphics) that contains the hand-traced contours in the XCF file * `klf14_b6ntac_training_v2`: Same as `klf14_b6ntac_training`, but the hand-traced data set was cleaned up to remove small contours of dubious cells, or cells that are fully overlapped by others * `klf14_b6ntac_training_non_overlap`: Directory with intermediate images to train the networks. These images are generated by script [`klf14_b6ntac_training_non_overlap`](https://github.com/MRC-Harwell/cytometer/blob/main/scripts/klf14_b6ntac_exp_0077_generate_non_overlap_training_images.py) * `klf14_b6ntac_training_augmented`: Directory with intermediate images used to train the networks (using augmentation to reduce overfitting). These images are generated by script [`klf14_b6ntac_exp_0078_generate_augmented_training_images.py`](https://github.com/MRC-Harwell/cytometer/blob/main/scripts/klf14_b6ntac_exp_0078_generate_augmented_training_images.py) * `klf14_b6ntac_seg`: Deprecated. Directory to store whole slide coarse segmentations in old experiments (e.g. `klf14_b6ntac_exp_0076_generate_training_images.py`). Of little interest for most users * `klf14_b6ntac_results`: Deprecated. Directory to store miscellanea output from some experiments. Of little interest for most users ## Casero et al. (2021). "Klf14 mouse white adipose tissue histology DeepZoom files and AIDA annotations for visualisation of DeepCytometer white adipocyte segmentations" (doi: 10.5281/zenodo.5149005) ### `aida_data_Klf14_v8_images.7z` (16.9 GB) Histology images converted to DeepZoom so that they can be visualised with [AIDA](https://github.com/alanaberdeen/AIDA). To use this, decompress this file and put the resulting `images` directory in your `AIDA/dist/data/` directory. ### `aida_data_Klf14_v8_annotations.7z` (18 GB) White adipocyte segmentations in AIDA annotation `.json` files (one contour per cell, one file per whole slide). Each slide has the following files: * `SLIDENAME.json`: Soft link to the annotations file that we want to associate to slide `SLIDENAME.ndpi`, e.g. `SLIDENAME` = `KLF14-B6NTAC-PAT-39.2d 454-16 B1 - 2016-03-17 12.16.06` * `SLIDENAME.lock`: Empty file used to tell the pipeline that `SLIDENAME.ndpi` has already been processed or is being currently processed * `SLIDENAME_coarse_mask.npz`: File with the coarse tissue segmentation of `SLIDENAME.ndpi` and the internal state of the pipeline (execution times, steps, etc) * `SLIDENAME_exp_0106_auto.json`: Annotations (all segmentations without filtering from the Auto algorithm, i.e. segmentation without object overlap). Contours are grouped by the tile they were processed in * `SLIDENAME_exp_0106_auto_aggregated.json`: Filtered annotations (non-white adipocytes removed) of the Auto algorithm. All contours aggregated into a single tile * `SLIDENAME_exp_0106_corrected.json`: Annotations (all segmentations without filtering from the Corrected algorithm, i.e. segmentation with object overlap). Contours are grouped by the tile they were processed in * `SLIDENAME_exp_0106_corrected_aggregated.json`: Filtered annotations (non-white adipocytes removed) of the Corrected algorithm. All contours aggregated into a single tile To use this, decompress this file and put the resulting `annotations` directory in your `AIDA/dist/data/` directory.</pre>
Representative Sample Dataset for Resolution-Agnostic Tissue Segmentation in Whole-Slide Histopathology Images
<p>This is a representative sample from the dataset that was used to develop resolution-agnostic convolutional neural networks for tissue segmentation1 in whole-slide histopathology images.</p> <p>The dataset is composed of two parts: <strong>development set</strong> and <strong>dissimilar set</strong>.</p> <p>Sample images from the development set:</p> <ul> <li>breast_hne_00.tif</li> <li>breast_lymph_node_hne_00.tif</li> <li>tongue_ae1ae3_00.tif</li> <li>tongue_hne_00.tif</li> <li>tongue_ki67_00.tif</li> </ul> <p>Sample images from the dissimilar set:</p> <ul> <li>brain_alcianblue_00.tif</li> <li>cornea_grocott_00.tif</li> <li>kidney_cab_00.tif</li> <li>skin_perls_00.tif</li> <li>uterus_vonkossa_00.tif</li> </ul>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 2 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the second part of 14 parts of the full dataset (2/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 300ms, 400ms, 500ms, and echo time (TE) = 15ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 3 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the third part of 14 parts of the full dataset (3/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 300ms, 400ms, 500ms, and echo time (TE) = 20ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 12 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the twelfth part of 14 parts of the full dataset (12/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 600ms, 700ms, 800ms, and echo time (TE) = 30ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 5 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the fifth part of 14 parts of the full dataset (5/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 300ms, 400ms, 500ms, and echo time (TE) = 30ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 4 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the fourth part of 14 parts of the full dataset (4/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 300ms, 400ms, 500ms, and echo time (TE) = 25ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each of simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 11 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the eleventh part of 14 parts of the full dataset (11/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 600ms, 700ms, 800ms, and echo time (TE) = 25ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 10 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the tenth part of 14 parts of the full dataset (10/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 600ms, 700ms, 800ms, and echo time (TE) = 20ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 14 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the fourteenth and final part of 14 parts of the full dataset (14/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 600ms, 700ms, 800ms, and echo time (TE) = 40ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 6 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the sixth part of 14 parts of the full dataset (6/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 300ms, 400ms, 500ms, and echo time (TE) = 35ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 8 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the eighth part of 14 parts of the full dataset (8/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 600ms, 700ms, 800ms, and echo time (TE) = 10ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 13 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the thirteenth part of 14 parts of the full dataset (13/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 600ms, 700ms, 800ms, and echo time (TE) = 35ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p> <p> </p>
Datasets of "Influence of contrast and texture based image modifications on the performance and attention shift of U-Net models for brain tissue segmentation" Part 7 of 14
<p>This dataset is part of the work <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a>. This is the seventh part of 14 parts of the full dataset (7/14). It contains 3 sets of simulated T1 weighted brain volumes in 3 simulated scanning sequences of spin-echo. The parameters of simulated scanning sequences are respectively repetition time (TR) = 300ms, 400ms, 500ms, and echo time (TE) = 40ms. Under <strong>each</strong> simulated scanning sequence, there are 500 brain volumes.</p> <p>The segmentation labels for each tissue are contained in the first part which you may find at <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>The simulation process of this dataset involves two processes. The first is to simulate one brain under different simulated scanning sequences. For this, we use BrainWeb <a href="https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request">https://brainweb.bic.mni.mcgill.ca/cgi/bw/submit_request</a>. In the custom setting, we use spin-echo and apply image artifact the same as the default setting of this page. The second process is to transform each simulated brain from BrainWeb to different anatomical shapes. We use Human Connectome Project (HCP) 1200 subject data <a href="https://www.humanconnectome.org/study/hcp-young-adult">https://www.humanconnectome.org/study/hcp-young-adult</a> and randomly select 500 brains as anatomical references.</p> <p>Other details of this dataset can be found at <a href="https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full">https://www.frontiersin.org/articles/10.3389/fnimg.2022.1012639/full</a> where the details of the data construction are discussed.</p> <p>All parts of the whole dataset can be found at:</p> <p>Part 1: <a href="https://zenodo.org/record/7294916">https://zenodo.org/record/7294916</a></p> <p>Part 2: <a href="https://zenodo.org/record/7389550">https://zenodo.org/record/7389550</a></p> <p>Part 3: <a href="https://zenodo.org/record/7390382">https://zenodo.org/record/7390382</a></p> <p>Part 4: <a href="https://zenodo.org/record/7390741">https://zenodo.org/record/7390741</a></p> <p>Part 5: <a href="https://zenodo.org/record/7391205">https://zenodo.org/record/7391205</a></p> <p>Part 6: <a href="https://zenodo.org/record/7393060">https://zenodo.org/record/7393060</a></p> <p>Part 7: <a href="https://zenodo.org/record/7393174">https://zenodo.org/record/7393174</a></p> <p>Part 8: <a href="https://zenodo.org/record/7393347">https://zenodo.org/record/7393347</a></p> <p>Part 9: <a href="https://zenodo.org/record/7394250">https://zenodo.org/record/7394250</a></p> <p>Part 10: <a href="https://zenodo.org/record/7394667">https://zenodo.org/record/7394667</a></p> <p>Part 11: <a href="https://zenodo.org/record/7394939">https://zenodo.org/record/7394939</a></p> <p>Part 12: <a href="https://zenodo.org/record/7395031">https://zenodo.org/record/7395031</a></p> <p>Part 13: <a href="https://zenodo.org/record/7395620">https://zenodo.org/record/7395620</a></p> <p>Part 14: <a href="https://zenodo.org/record/7395622">https://zenodo.org/record/7395622</a></p>
Images supporting: Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation
<p>Two image datasets (as zip files) including all images analyzed in the manuscript Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation. Images are of pancreatic adenocarcinoma (PDAC) cystic spheroid samples grown in either BME or Matrigel. Some images have background noise in the form of iron oxide nanoparticles introduced to them.</p>
Xenopus tissue data for testing segmentation models
<pre>This dataset is of xenopus tissue imaged with the following settings and it comes with a trained UNET model for performing the segmentation of such tissues. In order to use the segmentation model please install the vollseg-napari plugin from the napari hub and the model will be automatically downloaded for usage. Dataset was acquired by Mari Tolonen and Jakub Sedzinski, (0000-0002-4395-9022,0000-0002-1788-0329) at the university of Copenhagen and the model was trained by Varun Kapoor at Kapoorlabs. A Z projection of 21 Z slices acquired by the ImageJ Z Projection plugin was performed on the original acquired data. ObjectiveSettings ID="Objective:0" Medium="Water" RefractiveIndex="1.333"</pre> <pre>LensNA="1.2000000000000002" Model="C-Apochromat 40x/1.2 W AutoCorr M27" NominalMagnification="40.0"</pre> <pre>Physical Size X="0.6918881841365326" Physical Size X Unit="µm" </pre> <pre>Physical Size Y="0.6918881841365326" Physical Size Y Unit="µm" </pre> <pre>Physical Size Z="2.0" Physical Size Z Unit="µm"</pre> <pre>Time interval frames 1-160: 182 sec Time interval frames 161-262: 283 sec</pre> <pre>SignificantBits="8" Type="uint8"></pre> <pre>Channel AcquisitionMode="LaserScanningConfocalMicroscopy" ExcitationWavelength="488.0" ExcitationWavelengthUnit="nm" Fluor="EGFP"</pre>
Data for "Segmenting functional tissue units across human organs using community-driven development of generalizable machine learning algorithms"
<p>This repository contains the data and external data used by teams in the Kaggle competition "HuBMAP+HPA - Hacking the Human Body" and is part of the paper "Segmenting functional tissue units across human organs using community-driven development of generalizable machine learning algorithms".</p> <p>The directories contain:</p> <p><strong>data.zip:</strong> The training and test data, including metadata, used in the Kaggle competition "HuBMAP + HPA - Hacking the Human Body".</p> <p><strong>Team_1.zip: </strong>External data used by the first place winning solution.</p> <p><strong>Team_2.zip: </strong>External data used by the second place winning solution.</p>
Trained Models for "Segmenting functional tissue units across human organs using community-driven development of generalizable machine learning algorithms"
<p>This repository contains the trained model weights for the baseline model and the winning solutions in the Kaggle competition "HuBMAP+HPA - Hacking the Human Body", and is part of the paper "Segmenting functional tissue units across human organs using community-driven development of generalizable machine learning algorithms".</p> <p>The directory contains:</p> <p><strong>trained_model_1_weights.zip: </strong>Trained model weights for first place solution (Team 1).</p> <p><strong>trained_model_2_weights.zip:</strong> Trained model weights for second place solution (Team 2).</p> <p><strong>trained_model_3_weights.zip: </strong>Trained model weights for third place solution (Team 3).</p> <p><strong>trained_model_weights_baseline.zip:</strong> Trained model weights for the baseline model.</p>
Root tissue segmentation dataset
<p>The PHDFM dataset is composed of fluorescence microscopy images of root tissue samples from <em>A. thaliana</em>, using the ratiometric fluorescent indicator 8‐hydroxypyrene‐1,3,6‐trisulfonic acid trisodium salt (HPTS). This semantic segmentation training dataset consists of 2D microscopy images (the brightfield channel for excitation at 405 nm), each containing a segmentation mask as an additional image channel (manually annotated by plant biologists). The segmentation masks classify pixels into the following 5 labels with the corresponding IDs: background (0), root tissue (1), early elongation zone (2), late elongation zone (3), and meristematic zone (4).</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.