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790 results for “Transcranial magnetic stimulation”
Dataset of ipsilateral motor-evoked potentials induced by transcranial magnetic stimulation
<p>The dataset includes 4244 trials of EMG recordings after ipsilateral TMS under muscle contraction. This data was used for the evaluation of the DiMEP toolbox https://pypi.org/project/dimep/</p> <p>All subjects provided written, informed consent before participation and following approval by the local ethics committee. Subjects had no contraindications to TMS. TMS was delivered with a MagVenture MagPro-R30 with MagOption and a MCF-B70 figure 8-coil at an orientation of 45° to the midsagittal plane (see figure 1A). First, the motor hotspot of the contralateral, i.e., right, extensor digitorum communis (EDC) was determined by applying 40 stimuli to the left hemisphere. 40% MSO was used as the starting intensity and increased in steps of 5% MSO in case no MEPs could be elicited. Next, at the locations of the three stimuli that resulted in the greatest MEP, i.e., the largest MEP peak-to-peak amplitude, additional three stimuli were applied. The stimulation location that consistently elicited the largest MEPs in the contralateral EDC was then selected as the hotspot. A neuro-navigation system (TMS Navigator, Localite GmbH, Germany) supported coil positioning throughout the measurements. In order to measure ipsilateral MEPs, TMS pulses were applied to the motor hotspot with 5s ± 1.25 s between pulses (at an intensity of 90% MSO). To increase the likelihood of exhibiting ipsilateral MEPs, subjects were requested to isometrically contract their left biceps brachii (BB) to 30% of its maximum voluntary contraction while receiving visual feedback of the BB activity relative to the required target level of contraction on a computer display. The electromyographical response (EMG) to TMS was recorded with a BrainProducts ExG bipolar amplifier from the ipsilateral EDC. All trials were divided into 1s segments, i.e., 500 ms before and after each TMS pulse, and sampled at 1000 Hz.</p>
Dataset supporting: Repetitive transcranial magnetic stimulation (rTMS) triggers dose-dependent homeostatic rewiring in recurrent neuronal networks
<p>This dataset supports the Figures in the preprint: 'Repetitive transcranial magnetic stimulation (rTMS) triggers dose-dependent homeostatic rewiring in recurrent neuronal networks' by Anil et. al., <a href="https://www.biorxiv.org/content/10.1101/2023.03.20.533396v1">2023</a>.</p> <p>The code used to genrate this data can be found on the github repository: <a href="https://github.com/swathianil">swathianil </a><a href="https://github.com/swathianil/homeostatic_structural_plasticity_rTMS"> /homeostatic_structural_plasticity_rTMS</a>.</p> <p>To interactively regenerate the figures, follow the Jupyter notebook, GraphPlotter, available in the repository.</p>
Theta Burst Transcranial Magnetic Stimulation of Fronto-parietal Networks: Modulation by Mental State
ClinicalTrials.gov study NCT04010461. IPD Sharing: YES. Countries: 1. Publications: 1.
A Case of Psychogenic Myoclonus Responding to a Novel Transcranial Magnetic Stimulation Approach: Rationale, Feasibility, and Possible Neurophysiological Basis
<p>Repetitive transcranial magnetic stimulation (rTMS) can relieve motor symptoms related to psychogenic movement disorders (PMDs), but the subtending neurophysiological basis is unclear. We report on a 50-year-old woman with a diagnosis of psychogenic myoclonus in the right lower limb, who was treated with a daily session (in the late morning/early afternoon) of 1 Hz rTMS over the left premotor cortex (PMC), five times a week for 6 weeks. Clinical data and EEG at rest were collected before and immediately and 2-month after the rTMS protocol completion. The patient reported a significant reduction of involuntary movement frequency and intensity and the related disability burden up to the follow-up. In parallel, any abnormality in terms of source current density within and connectivity between the frontal and parietal areas was reset. The short follow–up period, the lack of extensive neurophysiological measures, and the lack of control treatment represent the main limitation of the study. However, low-frequency rTMS over PMC seems a safe and promising approach for the management of psychogenic myoclonus owing to the combination of cortical neuromodulation and non-specific mechanisms suggesting cognitive-behavioral effects.</p>
Test dataset for "Rapid estimation of cortical neuron activation thresholds by transcranial magnetic stimulation using convolutional neural networks"
<p>Data corresponding to test dataset used in Aberra AS, Lopez A, Grill WM, Peterchev AV. (2022). "Rapid estimation of cortical neuron activation thresholds by transcranial magnetic stimulation using convolutional neural networks". bioRxiv. Dataset includes:</p> <ul> <li><em>simnibs/ -</em> SimNIBS mesh and E-field solution file used in test dataset (posterior-anterior TMS of M1 in <em>ernie</em> example mesh, meshed with mri2mesh pipeline)</li> <li><em>layer_data/ - </em>surface meshes used for placing and orienting neuron models and corresponding sampling grids for CNNs</li> <li><em>nrn_sim_data/ - </em>Thresholds from NEURON simulations for all 25 model neurons included in the study, each at 4,999-5,000 positions and 12 azimuthal orientations ("ground truth" for CNN) </li> <li><em>cell_data/</em> - Coordinates and morphology information for all model neurons</li> <li><em>weights/</em> - Trained 3D convolutional neural networks for estimating neuron model-specific TMS thresholds given input E-field distributions on a 3D grid (see code/manuscript for dimensions)</li> <li><em>est_data/ </em>- Output of trained CNNs on all E-field data for test dataset <em> </em></li> </ul> <p> </p>
Repetitive Transcranial Magnetic Stimulation for "Voices"
ClinicalTrials.gov study NCT00004980. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Repetitive Transcranial Magnetic Stimulation for Musculoskeletal Pain in Patients With Parkinson's Disease
ClinicalTrials.gov study NCT05537597. IPD Sharing: NO. Countries: 1. Publications: 6.
Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders
ClinicalTrials.gov study NCT03191266. IPD Sharing: YES. Countries: 1. Publications: 1.
Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression
ClinicalTrials.gov study NCT03363919. IPD Sharing: NO. Countries: 1. Publications: 9.
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity
ClinicalTrials.gov study NCT02268461. IPD Sharing: Not stated. Countries: 1. Publications: 22.
Transcranial Magnetic Stimulation in Spino-Cerebellar Ataxia
ClinicalTrials.gov study NCT01975909. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Neurocircuitry of Autism- fMRI and Transcranial Magnetic Stimulation Studies
ClinicalTrials.gov study NCT01553240. IPD Sharing: Not stated. Countries: 1. Publications: 8.
A Study to Evaluate Central Nervous System (CNS) Pharmacodynamic Activity of TAK-653 in Healthy Participants Using Transcranial Magnetic Stimulation (TMS)
ClinicalTrials.gov study NCT03792672. IPD Sharing: YES. Countries: 1. Publications: 1.
The Use of Navigated Transcranial Magnetic Stimulation (nTMS) in the Inhibition of Neurofunctional Regions of Interest
ClinicalTrials.gov study NCT04209023. IPD Sharing: NO. Countries: 1. Publications: 7.
An Evaluation of Safety and Feasibility Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Adolescents With Depression
ClinicalTrials.gov study NCT00587639. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Transcranial Magnetic Stimulation for "Voices"
ClinicalTrials.gov study NCT00308997. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease
ClinicalTrials.gov study NCT04482179. IPD Sharing: NO. Countries: 1. Publications: 42.
Transcranial Magnetic Stimulation for Tinnitus
ClinicalTrials.gov study NCT01104207. IPD Sharing: NO. Countries: 1. Publications: 2.
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
ClinicalTrials.gov study NCT06112093. IPD Sharing: YES. Countries: 1. Publications: 21.
Repetitive Transcranial Magnetic Stimulation for Treating Depression: A Functional Magnetic Resonance Imaging Study
ClinicalTrials.gov study NCT01162382. IPD Sharing: Not stated. Countries: 1. Publications: 5.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.