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Dataset results
26 results for “Transgenerational stress,”
Within- and transgenerational stress legacy effects of ocean acidification on red abalone (Haliotis rufescens) growth and survival
<p>Understanding the mechanisms by which individual organisms respond and populations adapt to global climate change is a critical challenge. The role of plasticity and acclimation, within and across generations, may be essential given the pace of change. We investigated plasticity across generations and life stages in response to ocean acidification (OA), which poses a growing threat to both wild populations and the sustainable aquaculture of shellfish. Most studies of OA on shellfish focus on acute effects, and less is known regarding the longer-term carryover effects that may manifest within or across generations. We assessed these longer-term effects in red abalone (<em>Haliotis</em> <em>rufescens</em>) using a multi-generational split-brood experiment. We spawned adults raised in ambient conditions to create offspring that we then exposed to high pCO<sub>2</sub> (1,180 μatm; simulating OA) or low pCO<sub>2</sub> (450 μatm; control or ambient conditions) during the first three months of life. We then allowed these animals to reach maturity in ambient common garden conditions for four years before returning the adults into high or low pCO<sub>2</sub> treatments for 11 months and measuring growth and reproductive potential. Early-life exposure to OA in the F1 generation decreased adult growth rate, even after 5 years, especially when abalone were re-exposed to OA as adults. Adult, but not early-life exposure, to OA negatively impacted fecundity. We then exposed the F2 offspring to high or low pCO<sub>2</sub> treatments for the first three months of life in a fully factorial, split-brood design. We found negative transgenerational effects of parental OA exposure on survival and growth of F2 offspring, in addition to significant direct effects of OA on F2 survival. These results show that the negative impacts of OA can last within and across generations, but that buffering against OA conditions at critical life-history windows can mitigate these effects.</p>
Data and analyses from: Context matters: A meta-analysis of the variable impacts of transgenerational and developmental plasticity on responses to stress
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Within- and transgenerational stress legacy effects of ocean acidification on red abalone (Haliotis rufescens) growth and survival
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Data of transgenerational effects of thermal stress in embryos of O. maya
<p>To evaluate the transgenerational effect of thermal stress on the cephalopod <em>Octopus maya</em>, this study experimentally tests the morphology, respiratory metabolism, antioxidant mechanisms, and oxidative stress indicators of the embryos incubated at two temperatures (24 and 30°C) produced by females acclimated at 24 (non-stressed) and 30°C (stressed). The data set is organized in such a form that researchers will have embryo morphometric data (eye diameter, arm length, mantle length, yolk length, egg length egg wide, and wet weight of O. maya. Also, there is the oxygen consumption and antioxidant defense enzymes, oxidant damage, and esterase activity of embryos from stressed and nonstressed females. The results demonstrate that, regardless of their incubation temperature, embryos from females acclimated at 30°C are smaller, show more accelerated development, and have higher respiratory rates than those from females acclimated at 24°C. These embryos confirmed a greater oxidative stress degree, as well as an increased amount of soluble carbonylated proteins and catalase activity as the main enzyme during the activation development stage (even the highest in the embryos incubated at 30°C). Finally, a collapse of the antioxidant defense system was observed, measured as lower both CAT activity and GSH concentrations. Additionally, soluble carbonylated proteins reduced and GST activity increased in embryos incubated at 30°C from females maintained at high temperatures in a clear deleterious and transgenerational effect of thermal stress on this octopus species.</p>
The transgenerational physiological and molecular data of Oryzias melastigma under seawater acidification stress
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Data for: Parent-specific transgenerational immune priming enhances offspring defense – unless heat stress negates it all
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Data from: Transgenerational plasticity following a dual pathogen and stress challenge in fruit flies
Background: Phenotypic plasticity operates across generations, when the parental environment affects phenotypic expression in the offspring. Recent studies in invertebrates have reported transgenerational plasticity in phenotypic responses of offspring when the mothers had been previously exposed to either live or heat-killed pathogens. Understanding whether this plasticity is adaptive requires a factorial design in which both mothers and their offspring are subjected to either the pathogen challenge or a control, in experimentally matched and mismatched combinations. Most prior studies exploring the capacity for pathogen-mediated transgenerational plasticity have, however, failed to adopt such a design. Furthermore, it is currently poorly understood whether the magnitude or direction of pathogen-mediated transgenerational responses will be sensitive to environmental heterogeneity. Here, we explored the transgenerational consequences of a dual pathogen and stress challenge administered in the maternal generation in the fruit fly, Drosophila melanogaster. Prospective mothers were assigned to a non-infectious pathogen treatment consisting of an injection with heat-killed bacteria or a procedural control, and a stress treatment consisting of sleep deprivation or control. Their daughters and sons were similarly assigned to the same pathogen treatment, prior to measurement of their reproductive success. Results: We observed transgenerational interactions involving pathogen treatments of mothers and their offspring, on the reproductive success of daughters but not sons. These interactions were unaffected by sleep deprivation. Conclusions: The direction of the transgenerational effects was not consistent with that predicted under a scenario of adaptive transgenerational plasticity. Instead, they were indicative of expectations based on terminal investment.
Data from: Transgenerational plasticity and environmental stress: do paternal effects act as a conduit or a buffer?
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Data from: Transgenerational plasticity following a dual pathogen and stress challenge in fruit flies
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Data from: Individual variation in plasticity dulls transgenerational responses to stress
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Data from: Effects of multi-generational stress exposure and offspring environment on the expression and persistence of transgenerational effects in Arabidopsis thaliana
Plant phenotypes can be affected by environments experienced by their parents. Parental environmental effects are reported for the first offspring generation and some studies showed persisting environmental effects in second and further offspring generations. However, the expression of these transgenerational effects proved context-dependent and their reproducibility can be low. Here we study the context-dependency of transgenerational effects by evaluating parental and transgenerational effects under a range of parental induction and offspring evaluation conditions. We systematically evaluated two factors that can influence the expression of transgenerational effects: single- versus multiple-generation exposure and offspring environment. For this purpose, we exposed a single homozygous Arabidopsis thaliana Col-0 line to salt stress for up to three generations and evaluated offspring performance under control and salt conditions in a climate chamber and in a natural environment. Parental as well as transgenerational effects were observed in almost all traits and all environments and traced back as far as great-grandparental environments. The length of exposure exerted strong effects; multiple-generation exposure often reduced the expression of the parental effect compared to single-generation exposure. Furthermore, the expression of transgenerational effects strongly depended on offspring environment for rosette diameter and flowering time, with opposite effects observed in field and greenhouse evaluation environments. Our results provide important new insights into the occurrence of transgenerational effects and contribute to a better understanding of the context-dependency of these effects.
Data from: Effects of multi-generational stress exposure and offspring environment on the expression and persistence of transgenerational effects in Arabidopsis thaliana
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Transgenerational inheritance of DNA hypomethylation in Daphnia magna in response to salinity stress.
GEO Series GSE107340. Daphnia magna. 15 samples. Type: Methylation profiling by high throughput sequencing.
Transgenerational inheritance of chronic adolescent stress: Effects of stress response and the amygdala transcriptome
GEO Series GSE108452. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming
GEO Series GSE185579. Mus musculus. 31 samples. Type: Methylation profiling by high throughput sequencing.
Stress Resets Transgenerational Small RNA Inheritance
GEO Series GSE129988. Caenorhabditis elegans. 24 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Evolution of phenotypic plasticity and transgenerational effects of heat stress in the nematode Caenorhabditis remanei
GEO Series GSE62841. Caenorhabditis remanei. 48 samples. Type: Expression profiling by high throughput sequencing.
Transgenerational tolerance to abiotic stresses induced by plant virus infection
GEO Series GSE214636. Nicotiana benthamiana. 12 samples. Type: Expression profiling by high throughput sequencing.
Transgenerational effects of paternal restraint stress in Drosophila
GEO Series GSE140950. Drosophila melanogaster. 42 samples. Type: Expression profiling by high throughput sequencing.
Intestine-to-germline transmission of epigenetic information transgenerationally ensures systemic stress resistance in C. elegans
GEO Series GSE119917. Caenorhabditis elegans. 8 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
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