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13 results for “Warning Signs”
Postural fall in systolic blood pressure is an useful warning sign in Dengue fever
<p><strong>Purpose</strong>: Capillary leak is the hallmark of development of severe dengue. A rise in hematocrit has been a major warning sign in WHO guidelines. Postural hypotension, which could reflect the intravascular volume reduction in capillary leak, has been noted as a warning sign in CDC and Pan American Health Organisation guidelines. We evaluated the diagnostic accuracy of Postural hypotension as a marker of development of severe dengue.</p> <p><strong>Methods</strong>: 150 patients admitted with dengue fever were recruited in this prospective observational study. Diagnostic accuracy of conventional warning signs (<span>abdominal pain, persistent vomiting, fluid accumulation, mucosal bleeding, lethargy, liver enlargement, increasing hematocrit with decreasing platelets)</span> and postural hypotension was evaluated.</p> <p><strong>Result</strong>: 23 (15.3%) subjects developed severe dengue. Multiple logistic regression analysis showed that Ascites/Pleural effusion and postural fall in systolic blood pressure of >10.33% had an odds ratio of 5.024(95%CI:1.11 – 22.75) and 11.369 (95% CI:2.27 – 56.87) respectively. Other parameters did not reach statistical significance. Sensitivity and specificity of Ascites/Pleural effusion were 82.6% and 88.2% for development of severe dengue, whereas postural fall in systolic blood pressure had sensitivity and specificity of 87% and 82.7%.</p> <p><strong>Conclusion</strong>: These findings present a strong case for including postural hypotension as a warning sign in patients with dengue fever, especially in resource-limited settings.</p>
Warning Signs of Squamous Cell Carcinoma and Prevention of SCC by at Risk Organ Transplant Recipients
ClinicalTrials.gov study NCT01127737. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Postural fall in systolic blood pressure is an useful warning sign in Dengue fever
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Smartphone-based Ambulatory Assessment of Early Warning Signs
ClinicalTrials.gov study NCT02782910. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Novel Visual Education Tool to Improve Recognition and Reporting of Postpartum Urgent Maternal Warning Signs
ClinicalTrials.gov study NCT06912776. IPD Sharing: NO. Countries: 1. Publications: 3.
Affective Disorders: Eliminate WArning Signs And REstore Functioning: AWARE
ClinicalTrials.gov study NCT04701827. IPD Sharing: YES. Countries: 1. Publications: 2.
Effect of Montelukast in Preventing Dengue With Warning Signs in Dengue Patients
ClinicalTrials.gov study NCT04673422. IPD Sharing: YES. Countries: 1. Publications: 21.
Feasibility and Acceptability of a Smartphone App to Assess Early Warning Signs of Psychosis Relapse
ClinicalTrials.gov study NCT03558529. IPD Sharing: UNDECIDED. Countries: 0. Publications: 17.
Efficacy of Dengue Infection With Warning Signs Treated With Dexamethasone (DengDex Study)
ClinicalTrials.gov study NCT05631405. IPD Sharing: NO. Countries: 1. Publications: 0.
Awareness About Warning Signs of Mental Illness Among Health Profession Students. A Quasi-Experimental Study
ClinicalTrials.gov study NCT06517381. IPD Sharing: YES. Countries: 1. Publications: 0.
Effectiveness Of High Dose Melatonin As Adjunctive Therapy For Dengue Fever With Warning Signs
ClinicalTrials.gov study NCT05034809. IPD Sharing: NO. Countries: 0. Publications: 0.
F.A.S.T.-BE FAST Stroke Warning Signs Study
ClinicalTrials.gov study NCT06483165. IPD Sharing: NO. Countries: 1. Publications: 0.
Plasma-derived exosomal miRNA profiling in dengue patients with and without warning signs
GEO Series GSE307678. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by array.
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