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10 results for “Zinc metabolism”
A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria- MD simulation files
<p>This folder contains the first and last frame of MD simulations conducted in this study. </p> <p>The Free-MD folder contains unconstrained MD simulation files for Dri1 (WT) and its variants (H16A, H21A, H79A, H16A:H21A, H16A:H79A, H21A:H79A and H79A:R90A)</p> <p>The SAXS-dirven MD folder contains SAXS data constrained MD simulation files for Dri1 WT, Dri1 H21A and Dri H79A:R90A with 3 different starting structures for variants. </p>
Metabolic effects of a high level of dietary zinc in piglet diets to induce immune competence
<p>There is increasing consumer pressure to reduce the use of therapeutic antibiotics in animal production. Solutions to this challenge require a multi-targeted approach, including use of particular functional ingredients, such as pre- and probiotics that are not only used to boost the growth and productivity but also to influence the development of immune competence and support responsiveness of the immune system at later age. In this context there is a large interest in the development and evaluation of nutritional interventions during early life stages in farm animal species. However, apart from effects on animal growth and productivity, there is lack of knowledge in livestock on ways to modify development of immune competence by nutritional manipulation. Thus an associated project is being conducted with the objective to evaluate effects of a “model intervention” in piglets to modify development of immune competence. The associated project investigates the effects of provision of diet with a high concentration of zinc (2790 mg/kg) over different time periods in post-weaned piglets as a “model intervention” for manipulation of immune competence, compared to a reference treatment, in which the animals are fed a diet with a basal level of zinc.</p> <p>The objective of the associated project is to investigate the effects of high concentration of zinc on functional and metabolic changes, including processes related to digestive functions of the gut, its integrity and barrier function, and on immunological processes as effected by the nutritional manipulation. In the associated project we already studied the effects of high concentration of zinc on growth performance, on composition and diversity of the microbiota in the gut, on genome-wide gene expression in intestinal tissue, and on several immune markers in blood. In this proposal we apply for funds to provide us with expertise and access to facilities in order to get a global view of the metabolic changes as induced by the high concentration of zinc by analyzing a range of metabolites in blood. </p>
Evaluation of Zinc Intake on Essential Fatty Acid Metabolism
ClinicalTrials.gov study NCT03451214. IPD Sharing: NO. Countries: 1. Publications: 1.
Copper acts synergistically with fluconazole in Candida glabrata by compromising drug efflux, zinc homeostasis and sterol metabolism
GEO Series GSE162741. Nakaseomyces glabratus. 12 samples. Type: Expression profiling by high throughput sequencing.
Zinc finger protein 251 deficiency impairs glucose metabolism through adipocyte hypertrophy
GEO Series GSE201300. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
A Comparison of the Metabolic Effects of Zinc-Amino Acid (ZnAA) Versus Zinc Gluconate
ClinicalTrials.gov study NCT06348056. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
CXXC zinc finger protein 1 (Cfp1) controls cardiomyocyte maturation by modifying histone H3K4me3 of structural, metabolic, and contractile related genes
GEO Series GSE240852. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
CXXC zinc finger protein 1 (Cfp1) controls cardiomyocyte maturation by modifying histone H3K4me3 of structural, metabolic, and contractile related genes (ChIP-Seq)
GEO Series GSE241021. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Aspergillus fumigatus ZnfA, a novel zinc finger transcription factor involved in calcium metabolism and caspofungin tolerance
GEO Series GSE167847. Aspergillus fumigatus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting zinc metabolism for breast cancer inhibition in mice
GEO Series GSE255284. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
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