Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
5,635
datasets available to search
ShareScore release 0.7.1
Dataset results
5,635 results for “affect”
Lab disease outcomes data evaluating how antibiotic tolerant vs. non-tolerant cell-free supernatant from Pseudomonas aeruginosa affects the interaction between a fungal pathogen (Batrachochytrium dendrobatidis) and amphibian (Rana sylvaticus), 2022.
Microbes living on hosts and in the environment can play a key role in helping hosts to combat pathogens. However, antibiotic-induced alterations to microbial metabolite production could disrupt this dynamic. Here, we investigated whether antibiotic tolerance influences the anti-pathogenic properties of host-associated (living on the host; biofilms) and environmental (living in the soil of water column; planktonic) microbes in vitro and in vivo. For our model host and pathogen, we used the amphibian (Rana sylvatica)-Batrachochytrium dendrobatidis (Bd) system. For our model host-associated (biofilm) and environmental (planktonic) microbes, we used four strains of Pseudomonas aeruginosa that vary in their tolerance to antibiotics and their biofilm-forming capabilities: Planktonic, non-antibiotic tolerant (ΔsagS/VC); Planktonic, antibiotic tolerant (ΔsagS::sagS_L154A); Biofilm, non-antibiotic tolerant (ΔsagS::sagS_D105A); Biofilm, antibiotic tolerant (ΔsagS::sagS). We collected cell-free supernatants (CFS) from each strain to examine the effects of metabolites. We conducted four experiments. In our pathogen-only exposures to test direct effects of metabolites on Bd, we exposed Bd zoospores to each P. aeruginosa CFS at six concentrations. After 11 days of growth, we measured relative abundance of Bd across each treatment. In our host-only exposures to test effects of metabolites on host disease outcomes, we placed R. sylvatica tadpoles in individual units containing each P. aeruginosa CFS. After 48 hours, water was changed into clean well water (no CFS). Bd zoospores were immediately added to each experimental unit following the water change. After 5 days of Bd exposure, we measured snout-vent length (SVL), mass, developmental stage, and Bd quantification in the mouthparts using qPCR for each tadpole. In our host-pathogen exposures to test interactive effects of metabolites on hosts in the presence of the pathogen, we conducted the same experiment as above. However, ins
Outdoor mesocosm study evaluating how mass, NaCl tolerance, and pesticide tolerance affect oxidative stress biomarkers (CAT, SOD, GR, GPx, TBARS) in larval wood frogs (Rana sylvatica) exposed to baseline and NaCl-contaminated conditions, 2019
Biomarkers of oxidative stress can aid in wildlife monitoring by allowing conservationists to detect sublethal environmental shifts. However, interpretation of stress responses can be complicated by multiple interacting factors (e.g., individual development, evolved physiological tolerance to stressors) which alter biomarker expression. Here, we investigated how individual ontogenetic traits and population-level tolerance traits influence oxidative stress responses under baseline and contaminated environmental conditions. For our model contaminant, we used NaCl (common freshwater contaminant due to factors such as coastal flooding, irrigation, airborne salt circulation, drought, runoff from road deicing salts). For our model wildlife populations, we used larval wood frogs (Rana sylvatica) from six noninteracting populations known to vary in two population-level tolerance traits: NaCl tolerance (calculated as average time to death from lethal NaCl exposure) and pesticide tolerance (determined by proxy of distance to agriculture - a consistent and highly repeatable relationship). At an outdoor research facility, R. sylvatica tadpoles were exposed to either baseline conditions (0 g/L NaCl added) or NaCl-contaminated conditions (1 g/L NaCl added for 21 days, then reduced to 0.5 g/L NaCl). Exposures were conducted in individual units with 40 replicates per population for each treatment. The experiment was terminated per individual to capture the full term of larval development (Developmental stage: Gosner stage 36), lasting between 33-48 days. For each individual, we measured mass, Snout-Vent-Length, and developmental stage before processing for biomarker expression. Individual homogenates were assayed for oxidative stress biomarkers superoxide dismutase (SOD; responsible for Reactive Oxygen Species capture and peroxide production), glutathione peroxidase (GPx; responsible for high-affinity peroxide reduction), catalase (CAT; responsible for low-affinity peroxide reducti
Row data for the experiment: "Clinical, psychosocial and demographic factors affect decisions in SLE people".
<p>These datasets correspond to the article titled: “Clinical, psychosocial and demographic factors affect decisions in SLE people”, which can be found at <a href="https://www.medrxiv.org/content/10.1101/2024.03.25.24304643v1.full.pdf">https://www.medrxiv.org/content/10.1101/2024.03.25.24304643v1.full.pdf</a></p> <p>Analysis scripts, and an explanation of variables, can be found at: <a href="https://github.com/NeuroGenomicsMX/Factors_affecting_decisions_in_SLE">https://github.com/NeuroGenomicsMX/Factors_affecting_decisions_in_SLE</a></p> <p>Abstract</p> <p><span>Neurological and psychiatric manifestations affect most lupus individuals and include depression, anxiety, mood disorders, and cognitive dysfunction. Although there is evidence supporting suboptimal decision-making in lupus and its association with glucocorticoids consumption, it is not clear what variables impact such decisions. The aim of this study is to explore how social, clinical, psychological, and demographic factors impact social and temporal decision-making in people with lupus. Through a within-subjects experimental-design, our participants responded to social, clinical, psychological, and demographic electronic questionnaires. Then, they participated in two behavioral economics experiments: the third-party dictator game, and the delay discounting task. Our results show that hostility, and age are essential predictors of social decisions, whereas obsessive-compulsiveness and anxiety better predict temporal decisions. These variables behave as expected, but anxiety shows unexpected results: most anxious people act patiently and prefer delayed but bigger rewards. Finally, clinical factors are critical decision predictors for social and temporal decisions. When people are in remission, they tend to impose higher punishment on those who violate the social norm, and they also tend to prefer immediate rewards. When taking glucocorticoids, they also prefer immediate rewards, and as the dosage of glucocorticoids intake increases, they tend to impose higher punishment on norm violators. Clinicians, researchers, and practitioners must consider the side effects of glucocorticoids on decision-making.</span></p>
Data from: Invasion timing affects multiple scales, metrics and facets of biodiversity outcomes in ecological restoration experiments (Missouri, 2009-2016)
Vegetation responses to experimental ecological restoration treatments at Tyson Research Centre of Washington University in Missouri, USA. These data include species-level cover responses to various factorial restoration treatments. Treatments were applied starting in 2009 and were measured in 2016. Treatment responses reflect these long term responses, but the dataset is comprised to one time point.
The Biomass and Plant Functional Traits of Leymus chinensis Affected by Genotypic Diversity and Soil Nitrogen Addition through a Two-year Experiment, Tianjin, China, 2021-2023
In order to investigate the effects of soil nitrogen addition on the genotypic diversity of Leymus chinensis, 12 genotypes of Leymus chinensis were used as plant material and a two-factor experimental design was carried out in this study. Factor one was genotypic diversity of L. chinensis, including three levels: mono-genotype (G1), three genotypes (G3), and six genotypes (G6). Factor two was the soil nitrogen addition level, which included four levels: no nitrogen addition (N0), 2.5 g N/(m²·a) nitrogen application (N2.5), 5 g N/(m²·a) nitrogen application (N5), and 10 g N/(m²·a) nitrogen application (N10). Each treatment had 12 combinations as replicates, and 12 genotypes of L. chinensis were used. The frequency of each genotype was standardized across all treatment levels of genotypic diversity × soil nitrogen addition. The experiment commenced in September 2021 and soil nitrogen was applied every 2 months. Plants were cultivated in the experimental field at Nankai University, but were moved to a greenhouse for overwintering from November to February each year. During the experiment, there were no stresses or disturbances such as shading, drought, or insect feeding; weeds were regularly removed.
A dataset recorded during development of an affective brain-computer music interface: calibration session
Open the record for dataset details and reuse information.
A dataset recorded during development of an affective brain-computer music interface: testing session
Open the record for dataset details and reuse information.
A dataset recorded during development of an affective brain-computer music interface: training sessions
Open the record for dataset details and reuse information.
Postnatal Affective MRI Dataset
Open the record for dataset details and reuse information.
Differential contributions of ventral striatum subregions in the motivational and hedonic components of the affective response to reward
Open the record for dataset details and reuse information.
EEG: Probabilistic Learning with Affective Feedback: Exp #2
Open the record for dataset details and reuse information.
EEG: Probabilistic Learning with Affective Feedback: Exp #1
Open the record for dataset details and reuse information.
Using the Tea Bag Index to unravel how interactions between an antibiotic (Trimethoprim) and endocrine disruptor (17a-estradiol) affect aquatic microbial activity: Supporting Dataset 1
<p>The constant release of complex mixture of pharmaceuticals, including antimicrobials and endocrine disruptors, into the aquatic environment. These have the potential to affect aquatic microbial metabolism and alter biogeochemical cycling of carbon and nutrients. We used the Tea Bag Index (TBI) for decomposition within a series of contaminant exposure experiments to test how interactions between an antibiotic (trimethoprim) and endocrine disruptor (17a-estradiol) affects microbial activity in an aquatic system. The TBI is a citizen science tool used to test microbial activity by measuring the differential degradation of green and rooibos tea as proxies for labile and recalcitrant organic matter decomposition. Here we present the raw data on pharmaceutical exposures and the mass loss of the Rooibos and Green tea bags within the experiment. From Tea Bag mass loss we then calculated the Stabilisation Factor (S) and Initial Decomposition Rate of the labile organic matter fraction.</p>
Characterization of a loss-offunction NSF attachment protein beta mutation in monozygotic triplets affected with epilepsy and autism using cortical neurons from proband-derived and CRISPR-corrected induced pluripotent stem cell lines
<p>RNA-seq data of matured cortical neurons (8-weeks old) derived from the induced pluripoent stem cells (iPSC) of control parents (CtrlF and CtrlM) and corrected proband. There are three replicates (Rep1, Rep2, Rep3) for each sample with Forwad read (R1_001.fastq.gz)</p> <p>CtrlF: Control Father sample</p> <p>CtrlM: Control mother sample</p> <p>NDD_01_Corr_Het: Heterozygous correction of NAPB mutation (c.354+2T>G) in NDD_01 proband</p> <p>NDD_05_Corr_Hom: Homozygous correction of NAPB mutation (c.354+2T>G) in NDD_05 proband</p>
Dataset to: Organic carbon stocks, quality and prediction in permafrost-affected forest soils in North Canada (CATENA) - Version 2 (Corrected)
<p><strong>Version update: Coordinates were not correct in previsous version and have been corrected now in version 2</strong></p> <p> </p> <p>Dataset to the manuscript: Schiedung et al. (2022, Catena) Organic carbon stocks, quality and prediction in permafrost-affected forest soils in North Canada ( <a href="https://doi.org/10.1016/j.catena.2022.106194">https://doi.org/10.1016/j.catena.2022.106194</a> )</p> <p>Data files, variables and parameter are described in <em>Var_names_dd_all.csv</em> for all data on each sample and <em>Var_names_dd_composites.csv </em>for all data on composited samples per site and depth. DRIFT data and corresponding explenation are in <em>Schiedung_CATENA_DRIFT_v1.1.zip.</em></p> <p> </p> <p><strong> </strong></p>
Sex affects transcriptional associations with schizophrenia across the dorsolateral prefrontal cortex, hippocampus, and caudate nucleus
<p>This is supplementary data and source data for the manuscript, <em>"Sex affects transcriptional associations with schizophrenia across the dorsolateral prefrontal cortex, hippocampus, and caudate nucleus"</em>.</p> <p><strong>Abstract</strong>: Schizophrenia is a complex neuropsychiatric disorder with sexually dimorphic features, including differential symptomatology, drug responsiveness, and male incidence rate. Prior large-scale transcriptome analyses for sex differences in schizophrenia have focused on the prefrontal cortex. Analyzing BrainSeq Consortium data (caudate nucleus: n=399, dorsolateral prefrontal cortex: n=377, and hippocampus: n=394), we identified 831 unique genes that exhibit sex differences across brain regions, enriched for immune-related pathways. We observed X-chromosome dosage reduction in the hippocampus of male individuals with schizophrenia. Our sex interaction model revealed 148 junctions dysregulated in a sex-specific manner in schizophrenia. Sex-specific schizophrenia analysis identified dozens of differentially expressed genes, notably enriched in immune-related pathways. Finally, our sex-interacting expression quantitative trait loci analysis revealed 704 unique genes, nine associated with schizophrenia risk. These findings emphasize the importance of sex-informed analysis of sexually dimorphic traits, inform personalized therapeutic strategies in schizophrenia, and highlight the need for increased female samples for schizophrenia analyses.</p>
Data to support the publication "Soil Water Retention as Affected by Management Induced Changes of Soil Organic Carbon: Analysis of Long-Term Experiments in Europe", https://doi.org/10.3390/land10121362
<p>Soil organic carbon content and water content at the different pressure points, as measured by Ioanna Panagea for the publication "Soil Water Retention as Affected by Management Induced Changes of Soil Organic Carbon: Analysis of Long-Term Experiments in Europe", https://doi.org/10.3390/land10121362 from the the long term experiments belonging in some of the SoilCare project partners. </p>
Data: DEAE-Dextran enhances the lentiviral transduction of primary human mesenchymal stromal cells from all major tissue sources without affecting their proliferation and phenotype
<p>This data set includes all the raw data collected for the following article: "DEAE-Dextran enhances the lentiviral transduction of primary human mesenchymal stromal cells from all major tissue sources without affecting their proliferation and phenotype"</p>
Proline and β-alanine influence bumblebee nectar consumption without affecting survival
<p>These files (.txt) contain the dataset used for analyses of bumblebee aminoacid consumption and survival in the article "Proline and β-alanine influence bumblebee nectar consumption without affecting survival" by Bogo G. et al., accepted for publication in Apidologie (2024, xx:xxx-xxx, DOI: xxx).</p>
Dataset for Sandboxing use case SUC2 related to cyber attacks affecting Wide Area Protection
<p><span>This dataset is related to the operation of the second KIOS CoE sandboxing use case (SUC2) which inclused 3 scenarios (S1-S3) which examins the behavious a WAP scheme of power grids in case of a short circuit fault and in case of two types of cyber attacks. The description of the architecture of the University of Cyprus/ KIOS CoE sandboxing environmnet used for extracting these datasets along with the full list of scenarios and their detailed implementation are described in the supporting documents.</span></p> <p><span>Brief description of each of the 3 scenarios of this SUC2 are provided below.</span></p> <p><span>The datasets for the first scenario (S1) of SUC2</span><span> examines the operation of a wide area protection scheme in a transmission line which receives data sent from PMUs at the two ends of the lines, when a short-circuit fault occurred in the range of the transmission line between buses 7 and 8 of the system. More details about the scenario SUC2/S1 related to this scenario's dataset can be found in Section </span><span>1.3.1</span><span> of the SUC2 supporting document. </span><span><span>The dataset includes electrical measurements of the current flow in line 7-8 (of the IEEE 9-bus system), in both magnitude and sinusoidal form</span><span>.</span><span> The dataset is provided in the form of time-series measurements available as MATLAB (.mat) and CSV files, which were recorded with a 30-second and 40-second time resolution, respectively. The measurements of RMS values were recorded by the Typhoon controller as they were sent by the two PMUs, while the sine wave measurements were recorder through the OPAL-RT</span></span></p> <p><span>The datasets for second scenario (S2) of SUC2 investigates the operation of a wide area protection scheme which receives data sent from PMUs when a MITM FDI cyber-attack is conducted on the measurements of bus 7</span><span>, virtually implemented within the sandboxing, and introduces a multiplicative change to the current measurements before they are received by the Typhoon controller via IEEE C37.118 protocol</span><span>. Section 1.3.2 of the SUC2 supporting document provides more details about the scenario related to this dataset. </span><span>This dataset includes electrical measurements of the current flow, in magnitude and sinusoidal format, of the transmission line between buses 7 and 8 of the <span>digital twin of the IEEE 9-bus system.</span> The dataset is provided in the form of time-series measurements available as MATLAB (.mat) and CSV files which were recorded with a 30-second and 40-second time resolution, respectively. The measurements of magnitude values were recorded by the Typhoon controller, while the data from the sinusoidal waveform were recorder by OPAL-RT. </span></p> <p><span>Thie dataset of the SUC2/S3 examines the operation of a wide area protection scheme which receives data sent from PMUs when a combined MITM with DoS cyber-attack is conducted, as actual attack, in the isolated communication network of the sandboxing environment, disrupting the C37.118 UDP communication exchanged between OPAL-RT 5707, where the digital twin of IEEE 9-bus system was implemented, and Typhoon controller. More details about this scenario associated to this dataset can be found in Section </span><span>1.3.3<span></span></span><span> of the supporting document of SUC2.</span></p> <p><span>This dataset includes electrical measurements of current’s flow magnitude of the transmission line between buses 7 and 8 of the <span>digital twin of the IEEE 9-bus system.</span> The dataset was recorded by the Typhoon controller, and it is provided in the form of time-series measurements available as MATLAB (.mat) and CSV files which were recorded with a 30-second and 40-second time resolution, respectively. In addition, the dataset includes network traffic packets captured as .pcapng<span> </span>and .csv files. <span> </span></span></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.