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555 results for “albumin”
Serum albumin domain structures in human blood serum by mass spectrometry and computational biology
<p>Contact prediction data generated by EPC-map used in the paper "Serum Albumin Domain Structures in Human Blood Serum by Mass Spectrometry and Computational Biology" by Rappsilber et al.</p>
Binding constants of clinical drugs and other organic ligands with human and mammalian serum albumins
<p>The dataset contains literature values of the experimental equilibrium binding constants of drugs and some other organic ligands with human and mammalian (predominantly bovine) serum albumins. There are 1755 records gathered from 346 original literature sources describing the albumin affinity of 324 different substances. The data were extracted from both articles and existing protein binding databases applying strict data selection rules in order to exclude the values influenced by the third-party compounds. For each experiment with a particular ligand–albumin system found in literature we provide (if possible) the following details: albumin source organism, ligand chemical name, canonical SMILES, InChIKey, the binding (either association <em>K<sub>a</sub></em> or dissociation <em>K<sub>d</sub></em>) constant value in molarity-based scale, temperature in K, albumin and ligand concentrations, buffer pH, composition, and concentration, experimental method, model used for the binding constant calculation, DOI or link to the source paper. For the results obtained using independent binding sites model, the average number of binding sites <em>n</em> is also provided. If two different types of binding sites were suggested, we put the second site-specific binding constant <em>K<sub>a2</sub></em> or <em>K<sub>d2</sub></em> and the number of the second-type sites<em> </em> <em>n</em><sub>2</sub> into separate columns. For some systems, the enthalpies of binding have also been determined either from the temperature dependence of the binding constant or using direct calorimetric measurements. Their values are also given in the respective column. The dataset can be used as the reference one, for the development of predictive models to calculate the binding constants, and for the choice of the experimental setup in the future albumin binding studies.</p>
Neonicotinoid trapping by the FA1 site of human serum albumin
<p><strong>Leboffe_et_al_docking_simulations:</strong> Input and output files derived from the docking simulations described in the manuscript "Neonicotinoid trapping by the FA1 site of human serum albumin" by Leboffe et al. More informations are given in the "README.txt" file.</p>
Human Serum Albumin Adductome as an Instant Dosimeter of the Potential Internal Exposure of PM2 .5
<p>This dataset contains observations and indicators for PM2.5 potential internal exposure (PIE) evaluation. The dataset including three csv files:</p> <ol> <li> Surface Plasmon Resonance (SPR) technology monitoring data of human serun albumin (HSA) -water soluble organic molecule( WSOM) interaction</li> <li>HSA-WSOM adductome abundance</li> <li>ADMET evaluation for major contributors</li> </ol> <p> </p> <p> </p>
Gemcitabine Plus Albumin-bound Paclitaxel In Patients With Advanced Metastatic Pancreatic Cancer
ClinicalTrials.gov study NCT00398086. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Nanoparticle Albumin-Bound (Nab) Paclitaxel/Cyclophosphamide in Early-Stage Breast Cancer
ClinicalTrials.gov study NCT00629499. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Treatment of Subarachnoid Hemorrhage With Human Albumin
ClinicalTrials.gov study NCT00283400. IPD Sharing: Not stated. Countries: 2. Publications: 11.
A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease
ClinicalTrials.gov study NCT01561053. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Bevacizumab and Temozolomide or Bevacizumab and Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed by S
ClinicalTrials.gov study NCT00626405. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
ClinicalTrials.gov study NCT02975882. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety of Plasma Exchange With Albumin in Patients With Amyotrophic Lateral Sclerosis
ClinicalTrials.gov study NCT02479802. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients of Different Ages With Metastatic Breast Cancer
ClinicalTrials.gov study NCT00609791. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Albumin in Acute Ischemic Stroke Trial
ClinicalTrials.gov study NCT00235495. IPD Sharing: Not stated. Countries: 4. Publications: 4.
Phase III Study of ABI-007(Albumin-bound Paclitaxel) Plus Gemcitabine Versus Gemcitabine in Metastatic Adenocarcinoma of the Pancreas
ClinicalTrials.gov study NCT00844649. IPD Sharing: Not stated. Countries: 11. Publications: 16.
A Safety and Efficacy Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia B
ClinicalTrials.gov study NCT01496274. IPD Sharing: Not stated. Countries: 10. Publications: 1.
Value of Glycated Albumin in Intervention of Glycemic Control in Chinese Patients With Type 2 Diabetes
ClinicalTrials.gov study NCT05227677. IPD Sharing: NO. Countries: 1. Publications: 2.
Albumin Replacement Therapy in Septic Shock
ClinicalTrials.gov study NCT03869385. IPD Sharing: NO. Countries: 1. Publications: 1.
Albumin-bound Paclitaxel (ABI-007) for Patients With Advanced Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT00540514. IPD Sharing: Not stated. Countries: 2. Publications: 9.
Furosemide and Albumin for Diuresis of Edema: A Pilot Randomized Controlled Trial
ClinicalTrials.gov study NCT02055872. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Long-Term Administration of Human Albumin in Participants With Decompensated Cirrhosis and Ascites
ClinicalTrials.gov study NCT03451292. IPD Sharing: NO. Countries: 14. Publications: 1.
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