Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
153
datasets available to search
ShareScore release 0.9.0
Dataset results
153 results for “alcohol consumption”
Average daily alcohol consumption
<p>Average daily alcohol consumption by sex and age group. Average and standard deviation. Population aged 15 years old and over that consumes alcoholic beverages more than once per month</p>
Unveiling the role of miRNAs from MSC-EVs in neuroinflammation and behavioral impairments induced by chronic alcohol consumption
<p><strong>Part of the project: "Unveiling the role of miRNAs from MSC-EVs in neuroinflammation and behavioral impairments induced by chronic alcohol consumption."</strong></p> <p>This dataset contains small RNA sequencing data derived from extracellular vesicles (EVs) isolated from human adipose tissue-derived mesenchymal stem cells (MSC-EVs). The data was generated to study the potential therapeutic effects of repeated intravenous administration of MSC-EVs on neuroinflammation, cognitive dysfunction, and addictive-like behaviors induced by chronic alcohol consumption.</p> <p>Total RNA from MSC-EVs was extracted using the Total Exosome RNA Isolation Kit (Invitrogen). Small RNA libraries were constructed with the Small RNA-Seq Library Prep Kit (Lexogen) and sequenced on the Illumina NextSeq 550 platform with a 1 x 150 bp read length. The raw sequencing data are provided in fastq format.</p> <p> </p> <div> </div>
Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS, and impact on esophageal cancer risk in Japanese
<p><span>An East Asian-specific variant on <em>aldehyde</em> <em>dehydrogenase</em> <em>2</em> (<em>ALDH2</em> rs671, G>A) is the major genetic determinant of alcohol consumption. We performed an rs671 genotype-stratified genome-wide association study (GWAS) meta-analysis in up to 175,672 Japanese individuals to uncover additional loci associated with alcohol consumption in an rs671-dependent manner. Three loci (<em>GCKR</em>, <em>KLB</em>, and <em>ADH1B</em>)</span> <span>satisfied the genome-wide significance threshold in wild-type homozygotes (GG), whereas six loci (<em>GCKR</em>, <em>ADH1B</em>, <em>ALDH1B1</em>, <em>ALDH1A1</em>, <em>ALDH2</em>, and <em>GOT2</em>) did so in heterozygotes (GA). Of these, five loci showed genome-wide significant interaction with rs671. Genetic correlation analyses revealed ancestry-specific genetic architecture in heterozygotes. Subsequent polygenic risk scoring depicted interactions highlighted by stratified GWAS. Further, most discovered loci showed significant effects on risk of esophageal cancer, a representative alcohol-related disease, and multiple other phenotypes. Our results identify the genotype-specific genetic architecture of alcohol consumption and reveal its potential impact on alcohol-related disease risk.</span></p>
Addressing Heavy Alcohol Use Consumption With Kudzu
ClinicalTrials.gov study NCT03709043. IPD Sharing: NO. Countries: 1. Publications: 0.
The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes
ClinicalTrials.gov study NCT02840877. IPD Sharing: NO. Countries: 1. Publications: 3.
Varenicline to Reduce Alcohol Consumption in Heavy Drinkers
ClinicalTrials.gov study NCT00695500. IPD Sharing: NO. Countries: 1. Publications: 4.
Study of Mobile Phone Delivered Intervention to Reduce Alcohol Consumption
ClinicalTrials.gov study NCT02158949. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Levetiracetam (Keppra) on Alcohol Consumption
ClinicalTrials.gov study NCT01168687. IPD Sharing: Not stated. Countries: 1. Publications: 22.
Nursing Counseling to the Change of Behavior of Alcohol Consumption in Patients in HAART
ClinicalTrials.gov study NCT04054466. IPD Sharing: NO. Countries: 1. Publications: 22.
Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS, and impact on esophageal cancer risk in Japanese people
Open the record for dataset details and reuse information.
Data from: Predictors of alcohol consumption among in-school adolescents in the Central Region of Ghana: a baseline information for developing cognitive-behavioural interventions
Background and purpose: Despite a recent shift in school going adolescents' engagement in health compromising behaviours has serious socio-economic implications on developing societies, it is surprising that baseline information through research that would influence planned interventions is sparse. The purpose of this study was to investigate the prevalence of alcohol drinking behaviours among in-school adolescents in the Junior High Schools (JHS) in the Central Region of Ghana. Methods and results: Using a descriptive cross-sectional design, multistage sampling procedures were used to sample 1400 school going adolescents in JHS in the Central Region. Preliminary results using simple frequencies and percentages revealed 42% alcohol drinking prevalence in the region. High prevalence of drunkenness (73%, n = 405) and early exposure to alcohol drinking when students were in primary school (52%, n = 286) were noted. Community festivals and use of alcohol as a form of medicine were enabling factors of alcohol consumption in the region. Binary logistic regression analysis also showed that geographical location was a significant predictor of alcohol drinking among school going adolescents, with students in the southern and central part of the region at greater risks of drinking alcohol than those from the northern part (OR = .696, 95% CI = 0.52-926, p = .013). However, no statistical significant variations were found in the odds of drinking alcohol within age (OR = 1.13, 95% CI = 0.86-1.48, p = .370), gender (OR = .81, 95% CI = 0.65-1.01, p = .06), religious affiliation (OR = 1.33, 95% CI = 0.94-1.89, p = .10), parental communication (OR = .86, 95% CI = 0.66-1.06, p = .13), academic performance (OR = 1.07, 95% CI = 0.79-1.45, p = .05) and socioeconomic status (OR = 1.20, 95% CI = 0.95-1.53, p = .12). Conclusions: With this baseline data, it was recommended that schools' curricula should include preventive cognitive-behavioural interventions that teach drug resistance skills and anti-drug norms. These interventions would foster the development of requisite knowledge and social skills (e.g., developing competence) for resisting social and peer influences that may trigger alcohol use and perhaps other drugs. Potentially, the motivation for alcohol use among school going adolescents in the region would be minimized, if not prevented.
Data for the systematic review of OR modelling for alcohol consumption and its consequences
<p>This file contains the data of the 182 papers that were relevant for the literature review, which was used to produce the plots and analysis for this paper. </p>
Effects of Alcohol Consumption on Oxidative Stress in a Sample of Patients Recruited in a Dietary Center in a Southern University Hospital: A Retrospective Study
<p><em>Background and objectives</em>: The aim of this retrospective study was to evaluate the effects of alcohol consumption on oxidative stress. <em>Materials and Methods</em>: The study was conducted by analyzing the increase in lipid peroxidation, the reduction of antioxidant defenses and the alteration of the oxidation/antioxidant balance after the administration of ethanol in 25% aqueous solution (<em>v</em>/<em>v</em>) at a concentration of 0.76 g/kg of body weight daily in two doses for 3 days. The changes in oxidative stress indices were investigated by standard methods previously described. <em>Results</em>: Ethanol administration has determined a significant increase in plasma levels of lipid hydroperoxide (LOOH), malonilaldehyde (MDA) and oxidized glutathione (GSSH), and a decrease in total antioxidant capacity (TAC), reduced glutathione (GSH) and GSH/GSSH ratio. <em>Conclusions</em>: In the proposed experimental condition, the excessive and repeated consumption of ethanol causes oxidative damage, as shown by the increase in lipid peroxidation, the reduction of antioxidant defenses and the alteration of the oxidation/antioxidant balance, which, at least in part, are responsible for the harmful effects of excess ethanol.</p>
Comparing the Efficacy of Several Popular Online Interventions to Reduce Hazardous Alcohol Consumption
ClinicalTrials.gov study NCT03060135. IPD Sharing: NO. Countries: 1. Publications: 2.
Alcohol Consumption: Norms, Identities, & Motivations
ClinicalTrials.gov study NCT06447350. IPD Sharing: NO. Countries: 1. Publications: 1.
Impact of Meal Composition and Alcohol Consumption on Postprandial Glycemic Control in Subjects With Type 1 Diabetes
ClinicalTrials.gov study NCT03320993. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Postprandial Insulin Secretion and Appetite Regulation After Moderate Alcohol Consumption
ClinicalTrials.gov study NCT00524550. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A Clinical Trial on the Efficacy of tDCS) in Reducing Alcohol Consumption in Non-abstinent Patients (REDSTIM)
ClinicalTrials.gov study NCT02505126. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Text Message Behavioral Intervention to Reduce Alcohol Consumption in Young Adults
ClinicalTrials.gov study NCT01688245. IPD Sharing: Not stated. Countries: 1. Publications: 2.
AURAIA Study : Impact Evaluation at 3 Months Follow-up of a Brief Motivational Intervention in Reducing Alcohol Consumption Among Adolescents Aged 16-24 in Pontchaillou Hospital Emergency Department i
ClinicalTrials.gov study NCT01435668. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.