Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
79
datasets available to search
ShareScore release 0.9.0
Dataset results
79 results for “alginment”
Fabrication, Characterization and Evaluation of an Alginate–Lignin Composite for Rare-Earth Elements Recovery
<p>This dataset contains the raw data for the publication "Fabrication, Characterization and Evaluation of an Alginate–Lignin Composite for Rare-Earth Elements Recovery" by Fila et al, published in Materials. The upload includes raw data of physicochemical characterizations of alginate-based composite, i.e. alginate-lignin, including BET, SEM, TG, XPS and XRD analyses. </p>
Applicability of new sustainable and efficient alginate-based composites for critical raw materials recovery: General composites fabrication optimization and adsorption performance evaluation
<p>This dataset contains the raw data for the publication "Applicability of new sustainable and efficient alginate-based composites for critical raw materials recovery: General composites fabrication optimization and adsorption performance evaluation" by Fila et al, published in Chemical Engineering Journal. The upload includes raw data of physicochemical characterizations of calcium alginate and its composites, i.e. alginate-biochar and alginate-clinoptilolite, including BET, SEM, TG, XPS and XRD analyses. </p>
3D bioprinted alginate-gelatin hydrogel patches containing cardiac spheroids recover heart function in a mouse model of myocardial infarction
<p>Datasets for Roche et al (2023), '3D bioprinted alginate-gelatin hydrogel patches containing cardiac spheroids recover heart function in a mouse model of myocardial infarction'.</p>
Compound Sodium Alginate Double Action Chewable Tablet Symptomatic Relief Study
ClinicalTrials.gov study NCT01869491. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Sustainable wastewater decontamination of chlortetracycline using kaolin-alginates beads: Practical applications and adsorption mechanisms
Open the record for dataset details and reuse information.
U(VI) adsorption in water by sodium alginate modified Bacillus megaterium
Open the record for dataset details and reuse information.
The Alginate Immobilization of Metabolic Enzymes (AIME) platform retrofits an estrogen receptor transactivation assay with metabolic competence
The U.S. EPA Endocrine Disruptor Screening Program utilizes data across the ToxCast/Tox21 high-throughput screening (HTS) programs to evaluate the biological effects of potential endocrine active substances (EAS). A potential limitation to the use of in vitro assay data in regulatory decision-making is the lack of coverage for xenobiotic metabolic processes. Both hepatic- and peripheral-tissue metabolism can yield metabolites that exhibit greater activity than the parent compound (bioactivation) or are inactive (bioinactivation) for a given biological target. Interpretation of biological effect data for both putative EAS, as well as other chemicals, screened in HTS assays may benefit from the addition of xenobiotic metabolic capabilities to decrease the uncertainty in predicting potential hazards to human health. The objective of this study was to develop an approach to retrofit existing HTS assays with hepatic metabolism. The Alginate Immobilization of Metabolic Enzymes (AIME) platform encapsulates hepatic S9 fractions in alginate microspheres attached to 96-well peg lids. Functional characterization across a panel of reference substrates for phase I cytochrome P450 enzymes revealed substrate depletion with expected metabolite accumulation. Performance of the AIME method in the VM7Luc estrogen receptor (ER) transactivation assay was evaluated across 15 reference chemicals and 48 test chemicals that yield metabolites previously identified as ER active or inactive. The results demonstrate the utility of applying the AIME method for identification of false positive and false negative target assay effects, reprioritization of hazard based on metabolism-dependent bioactivity, and enhanced in vivo concordance with the rodent uterotrophic bioassay. Integration of the AIME metabolism method may prove useful for future biochemical and cell-based HTS applications.
Printability, durability, contractility and vascular network formation in 3D bioprinted cardiac endothelial cells using alginate-gelatin hydrogels
<p>TBC</p>
Supporting Information videos: Ice-Template Crosslinked PVA Aerogels Modified with Tannic Acid and Sodium Alginate
<p>Vertical burning videos of different aerogels:</p> <p>Video S1: P5 aerogel during vertical burning.</p> <p>Video S2: P5T3A3 uncrosslinked aerogel during vertical burning.</p> <p>Video S3 and S4: Self-extinguished performance of P5T3A3 crosslinked aerogel.</p> <p> </p>
Dataset - Estimation of alginate purity and M/G ratio by methanolysis coupled with anion exchange chromatography
Open the record for dataset details and reuse information.
Global Transcriptomic Analysis of Topical Sodium Alginate Protection Against Peptic Damage in An In Vitro Model of Treatment-Resistant Gastroesophageal Reflux Disease
<p>PA= pepsin + Acid; "Sham + PA" means "Pretreatment + Treatment"</p> <p><span>Breakthrough symptoms </span>are thought to occur in roughly half of <span>all </span>gastroesophageal reflux disease (GERD) patients despite maximal acid suppression (proton pump inhibitor, PPI) therapy. Topical alginates have recently been shown to enhance mucosal defense against acid-pepsin insult during GERD. We aimed to examine potential alginate protection of transcriptomic changes in a cell culture model of PPI recalcitrant GERD. Immortalized normal-derived human esophageal epithelial cells underwent pretreatment with commercial alginate-based anti-reflux medications (Gaviscon Advance or Gaviscon Double Action), a matched-viscosity placebo control, or pH 7.4 buffer (sham) alone for 1 minute, followed by exposure to pH 6.0+pepsin or buffer alone for 3 minutes. RNA sequencing was conducted, and Ingenuity Pathway Analysis was performed with a false discovery rate of ≤0.01, and absolute fold-change of ≥<span>1.3. Pepsin-acid exposure disrupted gene expressions associated with epithelial barrier function, chromatin structure</span>, carcinogenesis, and inflammation<span>. Alginate formulations demonstrated protection by mitigating these changes and promoting extracellular matrix repair, downregulating proto-oncogenes, and enhancing tumor suppressor expression. </span>These data suggest molecular mechanisms by which alginates provide topical protection against injury during weakly acidic reflux and support a potential role for alginates in prevention of GERD-related carcinogenesis.</p>
The Effects of Alginate Ag Dressing in the Pressure Injury Patients
ClinicalTrials.gov study NCT05667831. IPD Sharing: NO. Countries: 1. Publications: 9.
α-Mangostin Hydrogel Film With Chitosan Alginate Base for Recurrent Aphthous Stomatitis (RAS)
ClinicalTrials.gov study NCT06039774. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Effect of Sodium Alginate on Appetite Sensation
ClinicalTrials.gov study NCT01101633. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Time and Cost-implications of Intraoral Scans Vs Alginate Impressions
ClinicalTrials.gov study NCT06345989. IPD Sharing: UNDECIDED. Countries: 1. Publications: 11.
The Effect of an Alginate Based Beverage on Weight Loss
ClinicalTrials.gov study NCT01231178. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Alginate-based Reflux Suppressant and Magnesium-aluminium Antacid Gel for Treatment of Heartburn in Pregnancy
ClinicalTrials.gov study NCT02470117. IPD Sharing: Not stated. Countries: 1. Publications: 7.
"Feasibility and Safety of the Calcium Alginate Hydrogel Sealant for the Treatment of Cryptoglandular Fistula-in-ano: Phase I/IIa Clinical Trial"
ClinicalTrials.gov study NCT04740086. IPD Sharing: NO. Countries: 1. Publications: 1.
Prospective, Comparative, Randomized, Controlled Trial on the Efficacy of the Treatment of Gastroesophageal Reflux Infant With Magnesium Alginate
ClinicalTrials.gov study NCT01858584. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Disease
ClinicalTrials.gov study NCT01338077. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.