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8 results for “allostatic load”

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dryad36/100

Cross-sectional and prospective data on Framingham risk score, allostatic load, and ankle brachial index among Puerto Rican adults from the Boston Puerto Rican Health Study

<p><strong>Background</strong><br> Puerto Ricans have higher odds of peripheral artery disease (PAD) compared with Mexican Americans. Limited studies have examined relationships between clinical risk assessment scores with PAD assessments.</p> <p><strong>Methods</strong><br> Using 2004-2015 data from the Boston Puerto Rican Health Study (BPRHS) (n = 370-583), cross-sectional, 5-y change and patterns of change in Framingham Risk Score (FRS) and allostatic load (AL) with ankle brachial index (ABI) at 5-y follow-up was assessed among Puerto Rican adults (45-75 y). Analysis were conducted in 2020. FRS and AL were calculated at baseline, 2-y and 5-y follow-up. Multivariable linear regression models examined cross-sectional and 5-y changes in FRS and AL with ABI at 5-y. Latent growth mixture modeling identified trajectories of FRS and AL over 5-y, and multivariable linear regression models were used to test associations between trajectory groups at 5-y.</p> <p><strong>Results</strong><br> Greater FRS at 5-y and increases in FRS from baseline were associated with lower ABI at 5-y (β = -0.149, p = 0.010; β = -0.171, p = 0.038, respectively). AL was not associated with ABI in cross-sectional or change analyses. Participants in low-ascending (vs. no change) FRS trajectory, and participants in moderate-ascending (vs. low-ascending) AL trajectory, had lower 5-y ABI (β = -0.025, p = 0.044; β = -0.016, p = 0.023, respectively).</p> <p><strong>Conclusions</strong><br> FRS was a better overall predictor of ABI, compared with AL. FRS may be a clinically feasible measure of PAD risk in Puerto Ricans, an understudied population. Additional research examining relationships between FRS and AL and development of PAD is warranted.</p>

opencc-zeroOct 2021View details →
dryad36/100

Cross-sectional and prospective data on Framingham risk score, allostatic load, and ankle brachial index among Puerto Rican adults from the Boston Puerto Rican Health Study

Open the record for dataset details and reuse information.

publicOct 2021View details →
dryad32/100

Diurnal pastoralism does not reduce juvenile recruitment nor elevate allostatic load in spotted hyenas

<p>1. Anthropogenic activity can have substantial effects on wildlife. These effects may vary according to the characteristics of the activity and the species involved. While effects on behavior are well-studied, studies of effects on fitness and physiology are scarce, particularly for group-living species.</p> <p>2. We exploited a natural experimental setup to investigate the effect of diurnal pastoralism on juvenile recruitment and allostatic load in a population of free-ranging spotted hyenas in the Ngorongoro Crater, Tanzania, over a 24-year period.</p> <p>3. Pastoralism was restricted to the territories of two of the eight study clans, allowing us to compare juvenile recruitment in exposed and unexposed clans. We also compared fecal glucocorticoid metabolite concentrations (fGMC) – a biomarker of an organism's allostatic load – between exposed and unexposed clans using 975 fecal samples from 475 hyenas.</p> <p>4. We found no detectable difference in juvenile recruitment nor fGMC between the exposed and unexposed clans, indicating that the pastoralism had no substantial deleterious effect on the spotted hyenas. The lack of a deleterious effect likely stems from the combined effect of the predictable and undisruptive nature of the pastoralism, the socio-ecology of spotted hyenas, and the Ngorongoro Crater's consistently abundant prey.</p> <p>5. Our findings demonstrate that exposure to anthropogenic activity may be compatible with the persistence of certain group-living species, especially if the overlap between the species' critical behaviors and the activity is limited. Our study thereby provides new perspectives for ecologists, conservation biologists, and stakeholders who seek to assess human-wildlife conflicts and balance the needs of local human communities and wildlife.</p>

opencc-zeroSep 2022View details →
ClinicalTrials.gov32/100

Effect of Vitamin D Supplementation on Allostatic Load and Chronic Stress Along Line of Control in Azad Jammu Kashmir

ClinicalTrials.gov study NCT06101589. IPD Sharing: NO. Countries: 1. Publications: 3.

closedIPD-NOFeb 2026View details →
dryad32/100

Diurnal pastoralism does not reduce juvenile recruitment nor elevate allostatic load in spotted hyenas

Open the record for dataset details and reuse information.

publicSep 2022View details →
ClinicalTrials.gov24/100

Impact of Periodontal Inflammation on Allostatic Load

ClinicalTrials.gov study NCT06978712. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov24/100

Associations of Socioeconomic Adversity and Sleep With Allostatic Load Among Toddlers

ClinicalTrials.gov study NCT03419871. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov20/100

A Trial Assessing Feasibility of Allostatic Load Biomarkers and CVD Risk Among Black Breast Cancer Survivors

ClinicalTrials.gov study NCT06852560. IPD Sharing: Not stated. Countries: 0. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →

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