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6 results for “antioxidant defences”
Warm acclimation alters antioxidant defences but not metabolic capacities in the Antarctic fish, Notothenia coriiceps
<p>The Southern Ocean surrounding the Western Antarctic Peninsula region is rapidly warming. Survival of members of the dominant suborder of Antarctic fishes, the Notothenioidei, will likely require thermal plasticity and adaptive capacity in key traits delimiting thermal tolerance. Herein, we have assessed the thermal plasticity of several cellular and biochemical pathways, many of which are known to be associated with thermal tolerance in notothenioids, including mitochondrial function, activities of aerobic and anaerobic enzymes, antioxidant defences,protein ubiquitination and degradation in cardiac, oxidative skeletal muscles and gill of <em>Notothenia coriiceps</em> warm acclimated to 4◦C for 22 days or 5◦C for 42 days. Levels of triacylglycerol (TAG) were measured in liver and oxidative and glycolytic skeletal muscles, and glycogen in liver and glycolytic muscle to assess changes in energy stores. Metabolic pathways displayed minimal thermal plasticity, yet antioxidant defences were lower in heart and oxidative skeletal muscles of warm-acclimated animals compared with animals held at ambient temperature. Despite higher metabolic rates at elevated temperature, energy storage depots of TAG and glycogen increase in liver and remain unchanged in muscle with warm acclimation. Overall, our studies reveal that <em>N. coriiceps</em> displays thermal plasticity in some key traits thatmay contribute to their survival as the Southern Ocean continues to warm.</p>
Raw data of Octopus maya embryos along the development: wet weight, oxygen consumption, antioxidant defence mechanisms and oxidative damage.
<p>Raw data on oxygen consumption and antioxidant defense mechanisms of Octopus maya embryos were maintained in laboratory conditions at 24°C. Those data were obtained during the embryo development. The antioxidant defense mechanisms and oxidant damage were also obtained from the ovary and the un-spawned eggs, allowing to us known how is the oxidant damage translated from the females to embryos in this octopus species. </p>
Warm acclimation alters antioxidant defences but not metabolic capacities in the Antarctic fish, Notothenia coriiceps
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Data from: Oxidative damage and antioxidant defence are assay and tissue dependent both in captive and in wild-caught bank voles (Myodes glareolus) before and after reproduction
1. Reproduction is costly and life-history theory predicts that current parental investment will result in lower survival or decreased future reproduction. The physiological mechanisms mediating the link between reproduction and survival are still under debate and elevated oxidative damage during reproduction has been proposed as a plausible candidate. 2. Previous studies of oxidative stress during reproduction in animals under natural conditions have been restricted to analyses of blood. Herein, we measured the level of oxidative damage to lipids (thiobarbituric-acid-reactive substances) and proteins (carbonyls) in the liver, kidneys, heart and skeletal muscles in free-living bank vole females from spring and autumn generations, before and after reproduction. Antioxidant defence in the liver and kidneys was also determined. We expected oxidative damage to tissues and hypothesized that the damage would be more uniform between tissues in wild animals compared to those breeding under laboratory conditions. 3. Considering all combinations of markers/tissues/generations, oxidative damage in females did not differ before and after reproduction in 12 comparisons, was lower after reproduction in 3 comparisons, and was higher after breeding in one comparison. The total glutathione was significantly increased after reproduction only in the liver of the autumn generation and there was no change in catalase activity. 4. Our results confirm – for the first time in the field – previous observations from laboratory studies that there is no simple link between oxidative stress and reproduction and that patterns depend on the tissue and marker being studied. Overall however, our study does not support the hypothesis that the cost of reproduction in bank voles is mediated by oxidative stress in these tissues.
Data from: Oxidative damage and antioxidant defence are assay and tissue dependent both in captive and in wild-caught bank voles (Myodes glareolus) before and after reproduction
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SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation
GEO Series GSE179066. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
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