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107
datasets available to search
ShareScore release 0.9.0
Dataset results
107 results for “antisense oligonucleotide”
Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy
ClinicalTrials.gov study NCT00159250. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Data For Mechanistic Insights into ASO-RNA Complexation: Advancing Antisense Oligonucleotide Design Strategies
<div>Available data from manuscript "Mechanistic Insights into ASO-RNA Complexation: Advancing Antisense Oligonucleotide Design Strategies"</div> <div> </div> <div>FOLDERS:</div> <div>1. STRUCTURES</div> <div>include starting, average and last snapshots</div> <div>2. RMSD</div> <div>rmsd for heavy atoms of whole complex, the hairpin (mRNA) and the aso</div> <div>3. RADGYR</div> <div>radius of gyration of heavy atoms for the whole complex</div> <div>4. RMSF</div> <div>rmsf by residue</div> <div>5. MOVIE</div> <div>trajectorie files (.tpr and .xtc) for heavy atoms each 0.5 ns</div> <div>6. INTERACTIONENERGIES</div> <div>1) ASO and hairpin nucleobases atoms (ASOBase-hairpinBase; specific interactions), 2) ASO and hairpin backbones atoms (ASOBac-hairpinBac; nonspecific), 3) ASO nucleobases and hairpin backbone atoms (ASOBase-hairpinBac), and 4) ASO backbone and hairpin nucleobases atoms (ASOBac-hairpinBase).</div> <div>7. HBOND</div> <div>hydrogen bonds between ASO and hairpin atoms and internal hydrogen bonds for the hairpin</div> <p>---------------------------------------------</p> <p>for more information contact johhor@chalmers.se</p>
Accessible light-controlled knockdown of cell-free protein synthesis using phosphorothioate-caged antisense oligonucleotides (Raw data)
<p>Raw data for publication "Accessible light-controlled knockdown of cell-free protein synthesis using phosphorothioate-caged antisense oligonucleotides" (https://chemrxiv.org/engage/chemrxiv/article-details/6389f2dbe6f9a1754b2876d7)</p>
Clinical Trial of BP1001 (L-Grb-2 Antisense Oligonucleotide) in CML, AML, ALL & MDS
ClinicalTrials.gov study NCT01159028. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Pilot Study of EZN-2968, an Antisense Oligonucleotide Inhibitor of HIF-1alpha, in Adults With Advanced Solid Tumors With Liver Metastases
ClinicalTrials.gov study NCT01120288. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis
ClinicalTrials.gov study NCT06451172. IPD Sharing: NO. Countries: 1. Publications: 4.
AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites
ClinicalTrials.gov study NCT02417753. IPD Sharing: NO. Countries: 1. Publications: 0.
Splice-switching antisense oligonucleotide controlling tumor suppressor REST is a novel therapeutic medicine for neuroendocrine cancer
GEO Series GSE245707. Homo sapiens. 30 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Treatment of MM cells with non-targeting (NT) or ILF2 targeting oligonucleotide antisenses (ASOs)
GEO Series GSE192944. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profiling of primary human aortic Vascular Smooth Muscle cells abrogated of NEIL3 mRNA via antisense oligonucleotides targeting NEIL3 exon 4
GEO Series GSE140789. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profile of breast cancer cells transfected with antisense oligonucleotides (ASO) against BRCA1 pseudogene (BRCA1P1)
GEO Series GSE112572. Homo sapiens. 12 samples. Type: Expression profiling by array.
Atrophin-1 Antisense Oligonucleotide Provides Robust Protection from Pathology in a Fully Humanized DRPLA Model
GEO Series GSE296072. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Generation 2.5 Antisense Oligonucleotides Targeting the Androgen Receptor and its Splice Variants Suppress Enzalutamide-Resistant Prostate Cancer Cell Growth
GEO Series GSE55345. Homo sapiens. 6 samples. Type: Genome variation profiling by genome tiling array.
Potential off-targets investigation of a lead antisense oligonucleotides targeting ABCA4 c.768G>T in retinal organoids
GEO Series GSE253344. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Identification and Characterization of a MAPT-targeting Locked Nucleic Acid Antisense Oligonucleotide Therapeutic for Tauopathies I
GEO Series GSE204930. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeted Antisense Oligonucleotide Treatment Rescues Developmental Alterations in Spinal Muscular Atrophy Organoids [bulk RNA-seq]
GEO Series GSE290979. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq analysis of MDA-MB-231_2b cells treated with control or TRIM37 specific antisense oligonucleotides
GEO Series GSE136617. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Alzheimer’s disease neuroinflammatory risk genes can be targeted with RNase-H active antisense oligonucleotides in human microglia
GEO Series GSE219284. Homo sapiens; Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Reversal of MECP2 duplication syndrome using genetic rescue and antisense oligonucleotides [ASO time point 2]
GEO Series GSE71234. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Alteration of target cleavage patterns and off-target reduction of antisense oligonucleotides incorporating 2-N-carbamoyl- or (2-pyridyl)guanine
GEO Series GSE228747. Homo sapiens. 24 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.