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37 results for “attrition”
Dataset for: Smoking does not accelerate leukocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts
<p>Summary dataset (.csv file) and R script (.R file) for the manuscript entitled:</p> <p>Smoking does not accelerate leukocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts.</p> <p>The column names are explained at the beginning of the R script.</p> <p> </p>
Effect of the Increased Nursing Attrition Rate on Nursing Administration Process during the Covid-19 Pandemic in a Selected Tertiary Care Hospital
<p><span>During<span> </span>the<span> </span>COVID-19<span> </span>outbreak,<span> </span>healthcare<span> </span>professionals,<span> </span>particularly<span> </span>nurses,<span> </span>were<span> </span>more<span> </span>prone to<span> </span>diseases.<span> </span>Globally<span> </span>attrition<span> </span>rate<span> </span>was<span> </span>high<span> </span>among<span> </span>nurses<span> </span>and<span> </span>during<span> </span>the<span> </span>pandemic,<span> </span>it<span> </span>increased because<span> </span>of<span> </span>various<span> </span>reasons<span> </span>such<span> </span>as<span> </span>the<span> </span>risk<span> </span>of<span> </span>infection,<span> </span>occupational<span> </span>and<span> </span>psychological<span> </span>stress, causing risk to their loved ones. This led to a chaotic situation where nurse managers were forced to implement specific strategic plans to deal with increased nurse attrition. This study aims<span> </span>to<span> </span>describe<span> </span>the<span> </span>impact<span> </span>of<span> </span>nurse<span> </span>attrition<span> </span>rate<span> </span>on<span> </span>nursing<span> </span>administration<span> </span>during<span> </span>COVID-19 at a selected tertiary care hospital. The research approach adopted in this study is descriptive cross-sectional. A total sample of 66 nurses involved in nursing administration. The data is collected through a structured questionnaire and the nurse attrition data during the COVID-19 pandemic period was collected from the interview method during the survey. Statistical tests used were frequency, percentage, mean, Standard Deviation (S.D). The study showed that there is a moderate impact of increased nurse attrition on nursing administration during the COVID-19 pandemic. The study led to the identification of gaps that need to be addressed in a similar crisis.</span></p>
Fig. 14. Relief high, rounded cusps. A in Functional Characterization of Ungulate Molars Using the Abrasion-Attrition Wear Gradient: A New Method for Reconstructing Paleodiets
Fig. 14. Relief high, rounded cusps. A: Kobus ellipsiprymnus AMNH 53484, left M1-M2; B: 53476, left M2; C: 53479, right M2; D: 53496, right M2; E: 53455, right M2; F: 53496, right M3; G: 53479, right M1; H: 53496, right M2; I: 53496, left M1; J: 53496, right M2; K: 53497, right M2.
Fig. 19. Relief low, blunt cusps. A in Functional Characterization of Ungulate Molars Using the Abrasion-Attrition Wear Gradient: A New Method for Reconstructing Paleodiets
Fig. 19. Relief low, blunt cusps. A: Equus grevyi AMNH 277427, right M1-M3; B: Equus burchelli AMNH 83601, left M1; C: 27749, right M1-M3; D: 165064, left M1; E: 82313, left M1- M3; F: 182315, right M1; G: 82316, left M2-M3; H: 82314, left M2-M3.
Fig. 18. Relief low, blunt cusps. A in Functional Characterization of Ungulate Molars Using the Abrasion-Attrition Wear Gradient: A New Method for Reconstructing Paleodiets
Fig. 18. Relief low, blunt cusps. A: Ceratotherium simum TE 5919, left M2; B: 5926, left M2; C: 5923, right M1; D: Equus burchelli AMNH 82036, right M2-M3; E: 82037, left M1; F: 119669, left M3; G: 54247, right M3; H: 119669, left M1; I: 165065, right M1-M2; J: 16062, left M1.
Data from: Telomere attrition with age in a wild amphibian population
<p>Telomere shortening with age has been documented in many organisms, but few studies have reported telomere length measurements in amphibians, and no information is available for growth after metamorphosis, nor in wild populations. We provide both cross-sectional and longitudinal evidence of net telomere attrition with age in a wild amphibian population of natterjack toads (<em>Epidalea calamita</em>). Based on age-estimation by skeletochronology and qPCR telomere length measurements in the framework of an individual-based monitoring programme, we confirmed telomere attrition in recaptured males. Our results support that toads experience telomere attrition throughout<br> their ontogeny, and that most attrition occurs during the first 1–2 years.We did not find associations between telomere length and inbreeding or body condition. Our results on telomere length dynamics under natural conditions confirm telomere shortening with age in amphibians and provide quantification of wide telomere length variation within and among age-classes in a wild breeding population.</p>
Attrition
<p>What is the real cost of losing an employee? The Center for American Progress analysis (November 2012) notes that a departing employee's costs can range from 16% to 213% of his or her annual salary, depending on the position. Employees may leave due to personal reasons, low job satisfaction, low salary, low environmental satisfaction, and other reasons. The loss of employees not only costs the company talent, but also imposes high costs on the company, including the cost of interviews, recruitment, and training. Therefore, predicting a company's employee turnover rate can help management accelerate actions and strategies by strengthening internal policies, such as reducing the risk of employee turnover through salary increases or training. This analysis uses data mining to analyze IBM employee turnover data, analyze the factors that lead to employee turnover, and provide valuable insights for preventing employee turnover.</p>
Supplementary material for: Phylogenetic biodiversity metrics should account for both accumulation and attrition of evolutionary heritage
<p>Phylogenetic metrics are essential tools used in the study of ecology, evolution and conservation. Phylogenetic diversity (PD) in particular is one of the most prominent measures of biodiversity, and is based on the idea that biological features accumulate along the edges of phylogenetic trees that are summed. We argue that PD and many other phylogenetic biodiversity metrics fail to capture an essential process that we term attrition. Attrition is the gradual loss of features and other sources of variety through causes other than extinction. Here we introduce `EvoHeritage', a generalisation of PD that is founded on the joint processes of accumulation and attrition of features. We argue that whilst PD measures evolutionary history, EvoHeritage is required to capture a more pertinent subset of evolutionary history including only components that have survived attrition. We show that EvoHeritage is not the same as PD on a tree with scaled edges; instead, accumulation and attrition interact in a more complex non-monophyletic way that cannot be captured by edge lengths alone. This leads us to speculate that the one-dimensional edge lengths of classic trees may be insufficiently flexible to capture the nuances of evolutionary processes. We derive a measure of EvoHeritage and show that it elegantly reproduces species richness and PD at opposite ends of a continuum based on the intensity of attrition. We demonstrate the utility of EvoHeritage in ecology as a predictor of community productivity compared with species richness and PD. We also show how EvoHeritage can quantify living fossils and resolve their associated controversy. We suggest how the existing calculus of PD-based metrics and other phylogenetic biodiversity metrics can and should be recast in terms of EvoHeritage accumulation and attrition.</p>
Data for: Dietary nucleotides can prevent glucocorticoid-induced telomere attrition in a fast-growing wild vertebrate
<p><span>T<span>elomeres are chromosome protectors that shorten during eukaryotic cell replication and in stressful conditions. Developing individuals are </span>susceptible <span>to telomere erosion when their growth is fast and resources are limited. This is critical because the rate of telomere attrition in early life is linked to health and life span of adults. The metabolic telomere attrition hypothesis (MeTA) suggests that telomere dynamics can respond to biochemical signals conveying information about the organism's energetic state. Among these signals are glucocorticoids, hormones that promote catabolic processes, potentially impairing costly telomere maintenance, and nucleotides, which activate anabolic pathways through the cellular enzyme target of rapamycin (TOR), thus preventing telomere attrition. During the energetically demanding growth phase, the regulation of telomeres in response to two contrasting signals—one promoting telomere maintenance and the other attrition—provides an ideal experimental setting to test the MeTa. We studied nestlings of a rapidly developing free-living passerine, the great tit (<em>Parus</em> <em>major</em>), that either received glucocorticoids (Cort-chicks), nucleotides (Nuc-chicks), or a combination of both (NucCort-chicks), comparing these with controls (Cnt-chicks). As expected, Cort-chicks showed telomere attrition, while NucCort- and Nuc-chicks did not. NucCort-chicks was the only group showing increased expression of a proxy for TOR activation (the gene telo2), of mitochondrial enzymes linked to ATP production (cytochrome oxidase and ATP-synthase) and a higher efficiency in aerobically producing ATP. NucCort-chicks had also a higher expression of telomere maintenance genes (shelterin protein TERF2 and telomerase TERT) and of enzymatic antioxidant genes (glutathione peroxidase and superoxide dismutase). The findings show </span>that nucleotide availability is crucial for preventing telomere erosion during fast growth in stressful environments. </span></p>
Interpretation Training to Reduce Anxiety: Evaluating Technology-based Delivery Models and Methods to Reduce Attrition
ClinicalTrials.gov study NCT03498651. IPD Sharing: YES. Countries: 1. Publications: 1.
Data from: Telomere attrition with age in a wild amphibian population
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Data for: Dietary nucleotides can prevent glucocorticoid-induced telomere attrition in a fast-growing wild vertebrate
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Supplementary material for: Phylogenetic biodiversity metrics should account for both accumulation and attrition of evolutionary heritage
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Data from: Telomere attrition and growth: a life-history framework and case study in common terns
The relationship between growth and age-specific telomere length, as a proxy of somatic state, is increasingly investigated, but observed patterns vary and a predictive framework is lacking. We outline expectations based on the assumption that telomere maintenance is costly and argue that individual heterogeneity in resource acquisition is predicted to lead to positive covariance between growth and telomere length. However, canalization of resource allocation to the trait with a larger effect on fitness, rendering that trait relatively invariant, can cause the absence of covariance. In a case study of common tern (Sterna hirundo) chicks, in which hatching order is the main determinant of variation in resource acquisition within broods, we find that body mass, but not telomere length or attrition, varies with hatching order. Moreover, body mass and growth positively predict survival to fledging, whereas telomere length and attrition do not. Using a novel statistical method to quantify standardized variance in plasticity, we estimate between-individual variation in telomere attrition to be only 12% of that of growth. Consistent with the relative invariance of telomere attrition, we find no correlation between age-specific body mass or growth and telomere attrition. We suggest that common tern chicks prioritize investment in long-term somatic state (as indicated by canalization of telomere maintenance) over immediate survival benefits of growth as part of an efficient brood reduction strategy that benefits the parents. As such, inter-specific variation in the growth-telomere length relationship may be explained by the extent to which parents benefit from rapid mortality of excess offspring.
Data from: Rapid growth accelerates telomere attrition in a transgenic fish
Background: Individuals rarely grow as fast as their physiologies permit despite the fitness advantages of being large. One reason may be that rapid growth is costly, resulting for example in somatic damage. The chromosomal ends, the telomeres, are particularly vulnerable to such damage, and telomere attrition thus influences the rate of ageing. Here, we used a transgenic salmon model with an artificially increased growth rate to test the hypothesis that rapid growth is traded off against the ability to maintain somatic health, assessed as telomere attrition. Results: We found substantial telomere attrition in transgenic fish, while maternal half-sibs growing at a lower, wild-type rate seemed better able to maintain the length of their telomeres during the same time period. Conclusions: Our results are consistent with a trade-off between rapid growth and somatic (telomere) maintenance in growth-manipulated fish. Since telomere erosion reflects cellular ageing, our findings also support theories of ageing postulating that unrepaired somatic damage is associated with senescence.
Flashy male Jamaican anoles (Anolis grahami) show accelerated telomere attrition
<p>Data on Jamaican Anoles dewlap size and colouration, bite force and telomere attrition</p>
Enrollment and Attrition Rate of Fashion and Textiles Students Dataset
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The TELO-SCOPE Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis
ClinicalTrials.gov study NCT04638517. IPD Sharing: YES. Countries: 1. Publications: 1.
Attrition in Pediatric Obesity Management
ClinicalTrials.gov study NCT05403658. IPD Sharing: NO. Countries: 1. Publications: 1.
Data from: Telomere attrition and growth: a life-history framework and case study in common terns
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