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4 results for “axon initial segment”
Ultrafast imaging recordings from the axon initial segment of neocortical layer-5 pyramidal neurons.
<p>This dataset contains imaging and whole-cell electrophysiological recordings from neocortical layer-5 pyramidal neuron from brain slices of the mouse.</p> <p>Electrophysiological recordings (at 20 kHz) are from the soma. Imaging data (10 kHz) are from lines along the axon initial segment (distal>proximal) with 500 nm pixel resolution. These correspond to:</p> <ul> <li>Sodium imaging (Figures 1 and S6).</li> <li>Voltage imaging (Figures 2,4,5,S4,S7)</li> <li>Calcium imaging (Figures 3,S3,S8).</li> </ul> <p>This dataset is used in the paper available online:</p> <p>Filipis L, Blömer LA, Montnach J, De Waard M, Canepari M. Nav1.2 and BK channels interaction shapes the action potential in the axon initial segment. bioRxiv, 2022. doi: 10.1101/2022.04.12.488116.</p>
Drosophila voltage-gated sodium channels are only expressed in active neurons and are localized to distal axonal initial segment-like domains
GEO Series GSE157202. Drosophila melanogaster. 2 samples. Type: Expression profiling by high throughput sequencing.
Changes in the primary cilia in Alzheimer’s disease early development is associated with alterations in the axon initial segment.
GEO Series GSE248779. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Neurofilament accumulations in Amyotrophic Lateral Sclerosis patients’ motor neurons impair structural axonal initial segment integrity
GEO Series GSE200474. Homo sapiens. 65 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.