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31 results for “baicalin”

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zenodo28/100

Figure 6 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 6 Anti-proliferation effect of EGCG and baicalin in combination treatment against EMT-6/V different doses of EGCG with a fixed dose of baicalin (70 µM).

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 17 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 17 Effect of baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), a combination of baicalin and EGCG (75 and 50 mg/kg/day) respectively, vincristine 2 mg/kg/every other day, combination with vincristine (75 and 50 mg/kg/day) for combination and (2 mg/kg/every other day) for vincristine, Positive control (PBS and tween 20%), and healthy group on serum AST average level measured by (IU/L) in EMT-6/P.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 18 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 18 Effect of baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), a combination of baicalin and EGCG (75 and 50 mg/kg/day) respectively, vincristine 2 mg/kg/every other day, combination with vincristine (75 and 50 mg/kg/day) for combination and (2 mg/kg/every other day) for vincristine, Positive control (PBS and tween 20%), and healthy group on serum AST average level measured by (IU/L) in EMT-6/V.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 13 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 13 The volume change (mm3) for treatment groups in vivo for EMT-6/P and EMT-6/V. Only statistically significant associations are shown. Positive control (PBS and tween 20%), baicalin 75 mg/kg/day, EGCG: 50 mg/kg/day, baicalin and EGCG combination 75 and 50 mg/kg/day respectively, vincristine 2mg/kg/every other day, and same doses were used in the triple therapy.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 22 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 22 Effect of baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), a combination of baicalin and EGCG (75 and 50 mg/kg/day) respectively, vincristine 2 mg/kg/every other day, combination with vincristine (75 and 50 mg/kg/day) for combination and (2 mg/kg/every other day) for vincristine, positive control (PBS and tween 20%), and healthy group on average creatinine measured by (mg/dl) in EMT-6/V.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 7 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 7 Caspase concentrations in (ng/ml) for each treatment group in EMT-6/V. Concentrations used were: baicalin 175 µM, EGCG 125 µM, baicalin and EGCG 140 and 100 µM respectively, vincristine 643 µg/ml, and positive control treated with MEM.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 10 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 10 A plot of change in average tumor size (mm³) vs. time in (days) of treatment in the EMT-6/P cell line.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 16 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 16 Effect of baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), a combination of baicalin and EGCG (75 and 50 mg/kg/day) respectively, vincristine 2 mg/kg/every other day, combination with vincristine (75 and 50 mg/kg/day) for combination and (2 mg/kg/every other day) for vincristine, positive control (PBS and tween 20%), and healthy group on serum ALT level measured by (IU/L) in EMT-6/V.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 15 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 15 Effect of baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), a combination of baicalin and EGCG (75 and 50 mg/kg/day) respectively, vincristine 2 mg/kg/every other day, combination with vincristine (75 and 50 mg/kg/day) for combination and (2 mg/kg/every other day) for vincristine, positive control (PBS and tween 20%), and healthy group on serum ALT level measured by (IU/L) in EMT-6/P.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 11 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 11 Tumor sizes in EMT-6/V after dissection at day 10 in all groups compared to each other, n = 7.

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zenodo28/100

Figure 1 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 1 In vivo experiment: groups of EMT-6/P and EMT-6/V inoculated mice, Treatment approaches were: baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), and vincristine (2 mg/kg/every other day). The same concentrations were used in the combination treatment and triple therapy.

opencc-by-4.0Mar 2024View details →
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Figure 19 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 19 ALT serum level (U/L) in different treatment groups. Concentrations used baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), a combination of baicalin and EGCG (75 and 50 mg/kg/day) respectively, vincristine 2 mg/kg/every other day, combination with vincristine (75 and 50 mg/kg/day) for combination and (2 mg/kg/every other day) for vincristine, positive control (PBS and tween 20%), and healthy group in EMT-6/P and EMT-6/V. Including the statistical correlations between groups.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 14 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 14 The volume change (mm3) for treatment groups in vivo for EMT-6/P and EMT-6/V. Only statistically significant associations are shown. Positive control (PBS and tween 20%), baicalin 75 mg/kg/day, EGCG: 50 mg/kg/day, baicalin and EGCG combination 75 and 50 mg/kg/day respectively, vincristine 2mg/kg/every other day, and same doses were used in the triple therapy.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 9 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 9 Tumor sizes of EMT-6/P after dissection at day 10 in all groups compared to each other, n = 7 except for the last two groups n = 6.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 8 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 8 Folds increase in caspase-3 activity and apoptosis induction, concentrations used were: baicalin 175 µM, EGCG 125 µM, baicalin, and EGCG 140 and 100 µM respectively, vincristine 643 µg/ml and positive control treated with MEM in EMT-6/V.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 3 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 3 Anti-proliferative effect of EGCG in single treatment against EMT-6/P and EMT-6/V cell lines.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 23 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 23 Creatinine serum levels (mg/dl) in different treatment groups. Concentrations used baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), a combination of baicalin and EGCG (75 and 50 mg/kg/day) respectively, vincristine 2 mg/kg/every other day, combination with vincristine (75 and 50 mg/kg/day) for combination and (2 mg/kg/every other day) for vincristine, positive control (PBS and tween 20%), and healthy group in EMT-6/P and EMT-6/V. Including the statistical correlations between groups.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 4 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 4 The sensitivity of EMT-6/P and EMT-6/V cell lines to vincristine was measured by testing decreasing concentrations of vincristine using the anti-proliferative assay (MTT).

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 5 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 5 Anti-proliferation effect of EGCG and baicalin in combination treatment against EMT-6/P different doses of EGCG with a fixed dose of baicalin (114 µM).

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 21 from: Awajan D, Abu-Humaidan AHA, Talib WH (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71: 1-20. https://doi.org/10.3897/pharmacia.71.e113446

Figure 21 Effect of baicalin (75 mg/kg/day), EGCG (50 mg/kg/day), a combination of baicalin and EGCG (75 and 50 mg/kg/day) respectively, vincristine 2 mg/kg/every other day, combination with vincristine (75 and 50 mg/kg/day) for combination and (2mg/kg/every other day) for vincristine, positive control (PBS and tween 20%), and healthy group on average creatinine measured by (mg/dl) in EMT-6/P.

opencc-by-4.0Mar 2024View details →

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