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12 results for “beta values”
BETA values from DNA methylation (selected differential regions)
<p><span>Studies of DNA methylation have revealed the biological mechanisms by which life adversity confers risk for later physical and mental health problems. What remains unknown is the "biologically embedding" of maternal adverse experiences resulting in maladaptive parenting and whether these epigenetic effects are transmitted to the next generation. This study focuses on neglectful mothering indexed by a severe disregard for the basic and psychological needs of the child. Using the Illumina Human Methylation 850K BeadChip in saliva samples, we identified genes with differentially methylated regions (DMRs) in those mothers with, versus those without, neglectful behavior (n = 51 vs 87) that present similar DMRs patterns in their children being neglected versus non-neglected (n = 40 vs 75). Mothers reported the emotional intensity of adverse life events. After covariate adjustment and multiple testing corrections, we identified 69 DMRs in the mother epigenome and 42 DMRs in the child epigenome that were simultaneously above the </span><span>α</span><span> = 0.01 threshold. The common set of nine DMRs contained genes related to childhood adversity, neonatal and infant diabetes, child neurobehavioral development, and other health problems such as obesity, hypertension, cancer, posttraumatic stress, and Alzheimer's disease; four of the genes were associated with maternal life adversity. Identifying a shared epigenetic signature of neglect linked to maternal life adversity is an essential step in breaking the intergenerational transmission of one of the most common forms of childhood maltreatment.</span></p>
Data from: Pioneer habitats drive high plant beta diversity and conservation value of mineral extraction sites
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BETA values from DNA methylation (selected differential regions)
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Predictive and Diagnostic Value of Tau and Beta-amyloid Markers in the Dementia of Parkinson's Disease
ClinicalTrials.gov study NCT02243982. IPD Sharing: Not stated. Countries: 1. Publications: 16.
Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to Extended-spectrum Beta-lactamase (ESBL) or Carbapenemase-producing Enterobacteriaceae: an Observational
ClinicalTrials.gov study NCT01764490. IPD Sharing: Not stated. Countries: 1. Publications: 4.
CpG methylation beta values and sample age for the advanced forensic biology lesson
<p>This dataset should be used for the practical of the "Advanced Forensic Biology" lesson. It has been slightly modified from the initial source (see below). It consists of two parts:</p> <p><strong>1) CpG methylation beta values</strong>: tabulated separated methylation beta values in a file called <a href="https://zenodo.org/api/files/9ba3592f-ebe3-442f-9dc6-8b9b29fb170d/cpg_methylation_beta_values.tsv?versionId=5c6942cf-cbfe-4249-a3d9-e2b8b475aa88">cpg_methylation_beta_values.tsv</a>.</p> <p><strong>2) Samples to chronological age </strong>: the relationship between sample identifiers and their chronological age in a tabulated separated file called <a href="https://zenodo.org/api/files/9ba3592f-ebe3-442f-9dc6-8b9b29fb170d/cpg_methylation_sample_age.tsv?versionId=49252b02-9066-4acc-baff-d892320acafc">cpg_methylation_sample_age.tsv</a>.</p> <p><strong>3) CpG identifier to gene symbol and annotation:</strong> a tabulated separated file containing the relationship between CpG island identifier, the corresponding gene and its functional annotation. <a href="https://zenodo.org/api/files/9ba3592f-ebe3-442f-9dc6-8b9b29fb170d/cpg_methylation_cpg_to_annotation.tsv">cpg_methylation_cpg_to_annotation.tsv </a><br> </p> <p> </p> <p><strong>Dataset provenance:</strong></p> <ul> <li>Bocklandt S, Lin W, Sehl ME, Sánchez FJ, Sinsheimer JS, Horvath S, Vilain E. Epigenetic predictor of age. PLoS One. 2011;6(6):e14821. doi: <a href="https://pubmed.ncbi.nlm.nih.gov/21731603/">10.1371/journal.pone.0014821.</a> Epub 2011 Jun 22. PMID: 21731603; PMCID: PMC3120753.</li> <li>GEO link: <a href="https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28746">https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28746</a></li> </ul>
Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus
ClinicalTrials.gov study NCT00600795. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Negative Predictive Value of Drug Provocation Tests to Beta-lactams
ClinicalTrials.gov study NCT02844712. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Double-blind, Randomized Controlled Study to Assess the Analgesic Effect of 2 g of Magnesium Dipyrone (Metamizol) and Changes in Plasma Beta-endorphin Immunoreactivity Values in Patients Undergoing El
ClinicalTrials.gov study NCT04595877. IPD Sharing: NO. Countries: 1. Publications: 0.
Negative Predictive Value and NIC of Beta-Lactam Antibiotics.
ClinicalTrials.gov study NCT04126096. IPD Sharing: NO. Countries: 1. Publications: 0.
The Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain and Sciatic Pain "BETA"
ClinicalTrials.gov study NCT05544656. IPD Sharing: YES. Countries: 1. Publications: 0.
Fig. 5 Cluster analysis with multiscale bootstrap values for a in Coupling impoverishment analysis and partitioning of beta diversity allows a comprehensive description of Odonata biogeography in the Western Mediterranean
Fig. 5 Cluster analysis with multiscale bootstrap values for a the Sørensen index and b the Simpson index. The number of IndVal significant species is also reported for each cluster
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.