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6 results for “bifurcation analysis”
Treatment Of Coronary Bifurcation Lesions: Stentcovering Of The Side Branch With And Without PCI Of The Side Branch: A Retrospective Analysis Of All Consecutive Patients
ClinicalTrials.gov study NCT01538186. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Theoretical conditions for the coexistence of viral strains with differences in phenotypic traits: a bifurcation analysis
We investigate the dynamics of a wild-type viral strain which generates mutant strains differing in phenotypic properties for infectivity, virulence, and mutation rates. We study, by means of a mathematical model and bifurcation analysis, conditions under which the wild-type and mutant viruses, which compete for the same host cells, can coexist. The coexistence conditions are formulated in terms of the basic reproductive numbers of the strains, a maximum value of the mutation rate, and the virulence of the pathogens. The analysis reveals that parameter space can be divided into five regions, each with distinct dynamics, that are organised around degenerate Bogdanov-Takens and zero-Hopf bifurcations, the latter of which gives rise to a curve of transcritical bifurcations of periodic orbits. These results provide new insights into the conditions by which viral populations may contain multiple coexisting strains in a stable manner.
Data from: Theoretical conditions for the coexistence of viral strains with differences in phenotypic traits: a bifurcation analysis
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Bifurcation Lesion Analysis and STenting / BLAST
ClinicalTrials.gov study NCT02316782. IPD Sharing: Not stated. Countries: 8. Publications: 0.
Single-cell analysis of cell fate bifurcation in the chordate Ciona
GEO Series GSE160701. Ciona robusta. 6 samples. Type: Expression profiling by high throughput sequencing.
data related to the article titled: "A Sex-based analysis from the RAIN-CARDIOGROUP VII study (veRy thin stents for patients with left mAIn or bifurcatioN in real life) on Left-main stenting
<p>This record contains raw data related to the article “"A Sex-based analysis from the RAIN-CARDIOGROUP VII study (veRy thin stents for patients with left mAIn or bifurcatioN in real life) on Left-main stenting"</p> <p> </p> <p>abstract: </p> <p><strong>Introduction.</strong> There is a lack of data on clinical outcomes of percutaneous coronary intervention (PCI) with ultrathin stents on unprotected left main (ULM) coronary artery comparing women and men.</p> <p><strong>Methods. </strong>All patients treated with ULM PCI with ultrathin stents (struts ≤ 81 µm) enrolled in the RAIN-cardiogroup VII Study were analysed according to a sex-assessment evaluation. Major adverse cardiovascular events (MACE: a composite of all cause death, myocardial infarction, target lesion revascularization [TLR] and stent thrombosis) were the primary end-point, whereas single components of MACE were the secondary end-points.</p> <p><strong>Results</strong>. Out of a cohort of 793 patients, 172 (21.7%) women and 621 (78.3%) men were included. Compared to men, women were older and less frequently smokers, had more frequently a history of previous PCI and presented more frequently with an acute coronary syndrome. Among women, ostial lesions were more prevalent and mean diameter stent was lower compared to men. After 13.4 (8.4-21.6) months, 32 (18.6%) women and 106 (17.1%) men experienced MACE (p=0.64). Censoring follow-up data at 3 years, no differences were observed in MACE (16.9 vs 14.7 per 100*pts/years, log-rank p=0.61) and their single components between women and men. At multivariate analysis, chronic kidney disease (HR 1.91: 1.23 -2.95, p=0.004) and acute coronary syndrome presentation (HR 1.84: 1.22-2.77, p=0.013) were independent predictors of MACE overall. Larger stent size (HR 0.65, 95% CI 0.48-0.89, p=0.007) and longer double antiplatelet therapy duration (HR 0.95, 95% CI 0.90-0.99, p=0.032) were associated with a reduced risk of MACE during the subsequent follow-up</p> <p><strong>Conclusion. </strong>Ultrathin stents offer low rates of MACE and TLR in the overall population without significant differences between sexes.</p>
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