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17 results for “bio-inspiration”
Bio-inspired apparatus to produce luminescent cavitation in a rigid walled chamber
<p>A mechanical device inspired by the sudden rotational motion of the pistol shrimp claw was developed. The apparatus consists of a limb with a V-shaped end, which fits into a socket forming a cylindrical compression chamber. Air bubbles of different sizes and in different positions inside the chamber were seeded to study their shape evolution in liquids when subjected to pressure pulses induced by the limb closure. Non-spherical shape dynamics, micro jets and photon emission were observed during bubble collapse. The proposed mechanism represents a low-cost technology useful in the study of cavitation near rigid boundaries of diverse geometries.</p> <p>Experimental data on limb motion and bubble dynamics were obtained by processing videos taken with a high-speed camera. Light signals were acquired with a photomultiplier and force signals were acquired using PVDF piezoelectric sensors. </p> <p>Numerical data describing limb motion were obtained by numerically solving a torque balance model, while radial dynamics curves were obtained by solving the Rayleigh-Plesset equation.</p> <p>Data files are presented in two types of extension .opj (and .opju) that can be opened and analyzed in OriginPro software and also .xlsx that can be opened and analyzed with Microsoft Excel. The name of each file corresponds to the Figure number used in the article. <br> <br> Two notebooks created in Mathematica are made available. One of them was used to simulate the dynamics of clamp closure and the other to estimate the pressure pulse generated during limb closure. The versions of these files are not the most up-to-date, <br> but they contain all the information necessary to reproduce the results presented in the article.</p>
CT Dataset associated with the paper: (PLOSONE) Modular robotic platform for precision neurosurgery with a bio-inspired needle: system overview and first in-vivo deployment
<p>Imaging dataset associated with the work entitled "Modular robotic platform for precision neurosurgery with a bio-inspired needle: system overview and first in-vivo deployment.", published in the journal PLOS ONE</p>
dataset related to article "A NOVEL BIO-INSPIRED STRATEGY TO PREVENT AMYLOIDOGENESIS AND SYNAPTIC DAMAGE IN ALZHEIMER'S DISEASE"
<p><strong>Levels of A</strong><strong>beta40, Abeta42 and aggregated Abeta</strong></p> <p><strong>results obtained from plaque count</strong></p> <p><strong>densitometric analysis of ctf and synaptic proteins</strong></p> <p><strong>levels of antibodies against Abeta42 and Abeta1-6</strong></p>
Data from: Bio-inspired imager improves sensitivity in near-infrared fluorescence image-guided surgery
Image-guided surgery can enhance cancer treatment by decreasing, and ideally eliminating, positive tumor margins and iatrogenic damage to healthy tissue. Current state-of-the-art near-infrared fluorescence imaging systems are bulky and costly, lack sensitivity under surgical illumination, and lack co-registration accuracy between multimodal images. As a result, an overwhelming majority of physicians still rely on their unaided eyes and palpation as the primary sensing modalities for distinguishing cancerous from healthy tissue. Here we introduce an innovative design, comprising an artificial multispectral sensor inspired by the Morpho butterfly's compound eye, which can significantly improve image-guided surgery. By monolithically integrating spectral tapetal filters with photodetectors, we have realized a single-chip multispectral imager with 1000× higher sensitivity and 7× better spatial co-registration accuracy compared to clinical imaging systems in current use. Preclinical and clinical data demonstrate that this technology seamlessly integrates into the surgical workflow while providing surgeons with real-time information on the location of cancerous tissue and sentinel lymph nodes. Due to its low manufacturing cost, our bio-inspired sensor will provide resource-limited hospitals with much-needed technology to enable more accurate value-based health care.
Towards bio-inspired polymer adhesives: Activation assisted via HOBt for grafting of dopamine onto poly(acrylic acid)
<p>The design of bio-inspired polymers has long been an area of intense study, however applications to the design of concrete admixtures for improved materials performance have been relatively unexplored. In this work we functionalized poly(acrylic acid) (PAA), a simple analogue to polycarboxylate ether admixtures in concrete, with dopamine to form a catechol-bearing polymer (PAA-g-DA). Synthetic routes utilizing hydroxybenzotriazole (HOBt) as an activating agent were examined for their ability in grafting dopamine to the PAA backbone. Previous literature using the traditional coupling reagent 1-Ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC) to graft dopamine to PAA were found to be inconsistent and the sensitivity of EDC coupling reactions necessitated a search for an alternative. Additionally, HOBt allowed for greater control over percent functionalization of the backbone, is a simple, robust reaction, and showed potential for scalability. This finding also represents a novel synthetic pathway for amide bond formation between dopamine and PAA. Finally, we performed preliminary adhesion studies of our polymer on rose granite specimens and demonstrated a 56% improvement in the median adhesion strength over unfunctionalized PAA. These results demonstrate an early study on the potential of PAA-g-DA to be utilized for improving the bonds within concrete.</p>
Data for Improving propulsive efficiency using bio-inspired intermittent locomotion
<p>Raw and processed data for the manuscript: Improving propulsive efficiency using bio-inspired intermittent locomotion</p> <p>Contains both static and free propulsion measurements</p>
Raw dataset for "A Bio-Inspired SONAR System for Autonomous Flying Drones".
<p>Created on Mon Sep 26, 2023<br> Written by Yasufumi Yamada</p> <p>This repository was uploaded for the original article entitled <br> "A Bio-Inspired SONAR System for Autonomous Flying Drones".</p> <p>This repository includes the raw dataset for Fig.1, Fig.2, and Fig.3.</p> <p>Note that, the ".data" format can be read by changing the format name to ".txt".</p> <p>all "chk_" files indicate signal data which was recorded with a sampling frequency of 1MHz. <br> chk_rxwv : time amplitude signal of the received sound.<br> chk_txwv : digital time amplitude signal for emission.<br> chk_env : Cross-correlation signal processed with received sound and digital emission sound. <br> Each data was conducted the Hilbert transform to extract the envelope of the cross-correlation signal. </p>
The Bio-Inspired Artificial Pancreas for the Home
ClinicalTrials.gov study NCT03740698. IPD Sharing: NO. Countries: 1. Publications: 5.
Towards bio-inspired polymer adhesives: Activation assisted via HOBt for grafting of dopamine onto poly(acrylic acid)
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Bio-inspired forward and backward swimming gaits resulting from fluid-structure interactions
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Bio-inspired organic electrosense transistor for impalpable perception
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Data from: Bio-inspired imager improves sensitivity in near-infrared fluorescence image-guided surgery
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Study on bio-inspired feet based on the cushioning and shock absorption characteristics of ostrich foot
<p>The African ostrich (<em>Struthio camelus</em>) perennially living in deserts is outstanding with remarkable speed, exceptional endurance and continuous locomotion. As the main actuator of high-speed running, the ostrich feet possess excellent cushioning and shock absorption capabilities. In this study, based on the elastic modulus scales and assembly modes of soft tissues and the functions of the metatarsophalangeal (MTP) joint, eight bio-inspired feet were designed by an engineering method. With the peak acceleration as the index, the cushioning performances of different bio-inspired feet on loose sand or solid ground were compared through impact tests at different heights and verified by simulating the impact processes of the bio-inspired feet on loose sand on the finite element software Abaqus. Meanwhile, the stress distribution and deformation of each component of the bio-inspired feet were also clarified. The 15-15-15 HA (hardness unit) bio-inspired feet showed lower peak acceleration and thereby better cushioning performance, but larger deformation, less-uniform stress distributions and thereby lower stability than the 15-35-55 HA bio-inspired feet. Sensitivity analyses showed the cushioning capacity of the bio-inspired feet was comparable to that of the ostrich foot when the material (elastic modulus) and spring (stiffness coefficient) were properly selected. In fact, the silicon rubbers with different hardness levels which simulate the elasticity modulus scales of the toe pad, fascia and skin, and the spring mechanism which simulates the functions of the MTP joint, work as an “integrated system”of cushioning and shock absorption.</p>
Bio-inspired Interlocking Micro-Patterning for Tunable, Switchable and Selective Adhesion in Wet and Dusty Environments
<p>Abstract of the related article: Achieving adhesion under unfavourable conditions, such as when van der Waals interaction is not available or in dust environments, is crucial in applications ranging from surgical sutures to wound-healing tapes, underwater adhesives, robotic grippers, and space grasping.<br>Interestingly, plants, animals, and microorganisms living in such environmental conditions, show surface morphological traits optimised to achieve mechanical interlocking. Thus, they achieve an effective work of adhesion thanks to the interplay of friction and interfacially-storeable elastic energy, which otherwise typically suppress adhesion.<br>In this work, we provide the design and fabrication fundamentals for achieving tailorable, switchable and robust mechanical adhesion under a general environmental condition, such as wet or dusty, bio-mimicking natural solutions.<br>A theoretical framework for the design of mechanical adhesion, based on mean field continuum contact mechanics, is suggested, and validated experimentally. This study can pave the way for the development of new technologies, to be employed in situations where conventional adhesives may be ineffective, such as for surfaces exposed to water, solvent vapors, lubricants, high temperatures, dusty environments, high vacuum, or aerospace applications, or processes where switching and selective adhesion is needed such as grasping and sorting applications in semiconductor industry.</p> <p>The files are named after the numbering of the Figure in which they are used.<br>Description of the scripts as following:</p> <p>- FigureS5_ABCD.nb is a mathematica script to visualize the normalized single pair interaction for spherical interlockers, relating the dimensionless axial force to the dimensionless axial position.</p> <p>- Figure6_AnalyticalModel.nb is used to obtain the theoretical probability density function of the distance between microstructures when they follow a uniform distribution over a circular area.</p> <p>-Figure5.nb is a mathematica script used to perform a parametric study on double conical interlockers, varying the R/I_0 ratio, in approach/recede motion in dilute/dense conditions</p> <p>-Figure6_xyz_123.py is a python script used to perform Montecarlo simulations, it computes the histogram of distances between points randomly spread (lattice distributed, uniformly distributed, quasi-random distributed) on a unit circle.</p> <p>-FigureS8B.nb is a mathematica script used to average all the force contributions during the detachment phase of double conical patterned surfaces in order to get the Equation of state of the system, relating the normalized pressure to the out of plane axial displacement.</p> <p>- FigureS5_EFGH.nb is a mathematica script used to perform a parametric study on spherical interlockers, varying the friction coefficient value, in approach/recede motion in dilute/dense conditions.</p> <p>- Figure4.nb is a mathematica script used to perform a parametric study on spherical interlockers, varying the R/I_0 ratio in dilute/dense conditions.</p> <p>- FigureS6_EFGH.nb is a mathematica script used to perform a parametric study on double conical interlockers, varying the friction coefficient value, in approach/recede motion in dilute/dense conditions.</p> <p>- FigureS8A.nb is a mathematica script used to average all the force contributions during the attachment phase of double conical patterned surfaces in order to get the Equation of state of the system, relating the normalized pressure to the out of plane axial displacement.</p> <p>- FigureS2.rar is a folder with images of the dust characterization (coarse.tif; fine.tif; extrafine.tif) with python scripts to analyse the said images (ImageAnalysis.py) and extract the histogram of the equivalent particle diameter (HistogramPlot.py)</p> <p><br>- FigureS6_ABCD.nb is a mathematica script to visualize the normalized single pair interaction for double conical interlockers, relating the dimensionless axial force to the dimensionless axial position.</p> <p> </p> <p> </p> <p> </p>
Hydroacoustic and hydrodynamic investigation of bio-inspired leading-edge tubercles on marine ducted thrusters
<p>Underwater radiated noise (URN) has a negative impact on the marine acoustic environment where it can disrupt marine creature's basic living functions such as navigation and communication. To control the ambient ocean noise levels due to human activities, international governing bodies such as the International Maritime Organisation (IMO) have issued non-mandatory guidelines to address this issue. Under such framework, the hydroacoustic performance of marine vehicles has become a critical factor to be evaluated and controlled throughout the vehicles' service life in order to mitigate the URN level and the role humankind plays in the ocean. This study aims to apply leading-edge (LE) tubercles of the Humpback whales' pectoral fins to a benchmark ducted propeller to investigate its potential in noise mitigation. This was conducted using CFD, where the high-fidelity Improved Delayed Detached Eddy Simulations (IDDES) in combination with the porous Ffowcs-Williams Hawkings (FW-H) acoustic analogy was used to solve the hydrodynamic flow-field and propagate the generated noise to the far-field. It has been found that the LE tubercles have shown promising noise mitigation capabilities in the far-field, where the OASPL at J = 0.1 was reduced to a maximum of 3.4dB with a maximum of 11dB reduction in certain frequency ranges at other operating conditions. Based on detailed flow analysis researching the fundamental vortex dynamics, this noise reduction is shown to be due to the disruption of the coherent turbulent wake structure in the propeller slipstream causing the acceleration in the dissipation of turbulence and vorticity induced noise.</p>
Evaluation of a Bio-inspired Coding Strategy for Cochlear Implant Users
ClinicalTrials.gov study NCT03726684. IPD Sharing: NO. Countries: 1. Publications: 18.
Hydroacoustic and hydrodynamic investigation of bio-inspired leading-edge tubercles on marine ducted thrusters
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.