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ShareScore release 0.7.1
Dataset results
32 results for “biocompatibility”
Dataset from "In silico assessment of collateral eddy current heating in biocompatible implants subjected to magnetic hyperthermia treatments"
<p>This dataset from the publication entitled "Dataset from "In silico assessment of collateral eddy current heating in biocompatible implants subjected to magnetic hyperthermia treatments" contains simulated data of magnetic hyperthermia treatments for three different indications: colorectal cancer, prostate cancer and head & neck cancer. Since the aim of the study is to evaluate the risk of thermal damage caused by the collateral heating of two common types of passive prostheses (hip and dental implants), eddy currents induced in these implants upon interacting with the externally applied ac field during treatment have been computed for all the evaluated regions. Two different alloys for the implants have been considered for each case as well: Ti6Al4V and CoCrMo. At the same time, besides temperature, the specific abosorption rate (SAR) have been also computed to work out the energy deposition in tissues.</p> <p>Calculations have been carried out using a het exchange model with and without thermoregulation.</p> <p>log-log SAR vs T plots have been obtained and proposed as a quick means to pre-check treatment feasibility in each patient. These graphs are thought to be included in treatment planning prior to the clinical procedure.</p> <p>Other parameters taken into account have been the treatment time (5 and 30 minutes), and the maximum tolerable temperature threshold (1 or 5 ºC, as indicated by the ICNIRP commission), all for three main types of tissues, namely fat, bone and muscle. Each tissue have been simulated using three different field intensities (5, 10 and 15 mT).</p> <p>The field frequency has been 300 kHz in all cases.</p> <p>The files "Dataset_description.doc" and "file_scheme.txt" contain the structure and description of the files that make up the dataset.</p> <p>UPDATES FROM PREVIOUS VERSIONS: simulations of the dental implant without thermoregulation have been added.</p>
Dataset for "Biocompatible Rhamnolipid Self-Assemblies with pH-Responsive Antimicrobial Activity"
<p>This dataset provides the raw data supporting the paper: Biocompatible Rhamnolipid Self-Assemblies with pH-Responsive Antimicrobial Activity. It comprises SAXS data (Figure 2, Figure 3, Figure 4, Figure 5, Figure S2 and Figure S4), cryo-TEM images (Figure 2D, Figure 4D, Figure 5D, Figure 5E), Zeta-potential measurment (Figure 7), DLS data (Figure 8, Figure S5, Figure S6, Figure S7, Figure S8 and Table S2), Antimicrobial activity data (Figure 9, Table 1, Figure S9, Figure S10, Figure S12, Figure S13, Figure S14, Figure S15, Figure S16 and Table S3), Cytotoxicity data (Figure 10), Colloidal stability images (Figure S1 and Figure S3) and Biofilm inhibition and biofilm eradication assay (Figure S11).</p><p> </p>
Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions
<p>This data corresponds to the following paper:</p> <p>Title: Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions<br> DOI: 10.1126/sciadv.add3643<br> Journal: Science Advances<br> Authors: Josh P. Peters, Arne Brahms, Vivian Janicaud, Maria Anikeeva, Eva Peschke, Frowin Ellermann, Arianna Ferrari, Dana Hellmold, Janka Held-Feindt, Na-mi Kim, Johannes Meiser, Konrad Aden, Rainer Herges, Jan-Bernd Hövener, Andrey N. Pravdivtsev</p> <p>In the upload the figures 2 - 6 are covered, so all figures from the main manuscript with acquired data.</p> <p> </p> <p>Original abstract for the manuscript:</p> <p>Dissolution dynamic nuclear polarization (dDNP) increases the sensitivity of magnetic resonance imaging by more than 10,000 times enabling <em>in vivo</em> metabolic imaging can be performed non-invasively in real-time. Here, we are developing a group of dDNP polarized tracers based on nicotinamide (NAM). We synthesized 1-<sup>15</sup>N-NAM and 1-<sup>15</sup>N nicotinic acid and hyperpolarized them with dDNP, reaching (13.0±1.9)% <sup>15</sup>N polarization. We found that the lifetime of hyperpolarized 1-<sup>15</sup>N-NAM is strongly field- and pH-dependent, with T<sub>1</sub> being as long as 41 s at a pH of 12 and 1 T while as short as a few seconds at neutral pH and fields below 1 T. The remarkably short 1-<sup>15</sup>N lifetime at low magnetic fields and neutral pH drove us to establish a unique pH neutralization procedure. Using <sup>15</sup>N dDNP and an inexpensive rodent imaging probe designed in-house, we acquired a <sup>15</sup>N MRI of 1-<sup>15</sup>N-NAM (previously hyperpolarized for more than an hour) in less than one second.</p>
Dataset for: Multivascular networks and functional intravascular topologies within biocompatible hydrogels
<p>Dataset for:</p> <p>Multivascular networks and functional intravascular topologies within biocompatible hydrogels</p> <p>Bagrat Grigoryan1,∗, Samantha J. Paulsen1,∗, Daniel C. Corbett2,∗, Daniel W. Sazer1, Chelsea L. Fortin2, Alexander J. Zaita1, Paul T. Greenfield1, Nicholas J. Calafat1, John P. Gounley3, Anderson H. Ta1, Fredrik Johansson2, Amanda Randles3, Jessica E. Rosenkrantz4, Jesse D. Louis-Rosenberg4, Peter A. Galie5, Kelly R. Stevens2,†, Jordan S. Miller1,†</p> <p>1Department of Bioengineering, Rice University, Houston, TX 77005, USA 2Department of Bioengineering, University of Washington, Seattle, WA 98195, USA 3Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA 4Nervous System, Somerville, MA 02143, USA 5Department of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, USA</p> <p>∗Equal contribution. †Corresponding authors. Email: ksteve@uw.edu (K.R.S.) and jmil@rice.edu (J.S.M.).</p> <p>Solid organs transport fluids through distinct vascular networks that are biophysically and biochemically entangled, creating complex 3D transport regimes that have remained difficult to produce and study. We establish intravascular and multivascular design freedoms with photopolymerizable hydrogels using food dye additives as biocompatible yet potent photoabsorbers for projection stereolithography. We demonstrate monolithic transparent hydrogels produced in minutes comprising efficient intravascular 3D fluid mixers and functional bicuspid valves. We further elaborate entangled vascular networks from space-filling mathematical topologies and explore the oxygenation and flow of human red blood cells during tidal ventilation and distension of a proximate airway. In addition, we deployed structured biodegradable hydrogel carriers in a rodent model of hepatic disease to highlight the potential translational utility of this materials innovation.</p>
A mechanoresponsive nucleic acid scaffold to control biological systems by biocompatible ultrasound
<p>Data sets used for main figures of the manuscript entitled 'A mechanoresponsive nucleic acid scaffold to control biological systems by biocompatible ultrasound'.</p>
Biocompatible Versus Non-coated Extracorporeal Circuits in Cardiac Surgery
ClinicalTrials.gov study NCT06612060. IPD Sharing: NO. Countries: 1. Publications: 3.
Evaluation of Biocompatibility and Performances of 4 Dialyzers in Different Mode Treatments
ClinicalTrials.gov study NCT03262272. IPD Sharing: NO. Countries: 1. Publications: 2.
Evaluation of the Biocompatibility of Cartridge Blood Set Versus Standard Blood Line
ClinicalTrials.gov study NCT00804453. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Research data supporting "In vivo biocompatibility and immunogenicity of metal-phenolic gelation"
<p>Research raw data supporting the publication:</p> <p>Bjornmalm M., et al., 2019, Chemical Science, DOI:101039/c9sc03325d</p>
Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers
ClinicalTrials.gov study NCT01484938. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)
ClinicalTrials.gov study NCT01476722. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Use of Biocompatible Thermoplastic Impregnated With Vancomycin as a Temporary Orthopedic Spacer
ClinicalTrials.gov study NCT07031999. IPD Sharing: NO. Countries: 0. Publications: 1.
Clinical Biocompatibility Evaluation of Contact Lens Coatings
ClinicalTrials.gov study NCT03034928. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Enhanced in vitro biocompatibility and osteogenesis of titanium immobilized with dopamine-assisted superparamagnetic Fe3O4 nanoparticles for hBMSCs
Open the record for dataset details and reuse information.
Biocompatibility and Discovery of the Potential Applications of Magnetite (Fe3O4) Nanoparticles
GEO Series GSE15248. Homo sapiens. 6 samples. Type: Expression profiling by array.
In vitro biocompatibility of Ti-Cp vs Ti-26Nb alloys on Saos-2 and THP-1 cells
GEO Series GSE197987. Homo sapiens. 8 samples. Type: Expression profiling by array.
Scalable production of human cortical organoids using a biocompatible polymer
GEO Series GSE232581. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Evaluating the utility of the Threshold of Toxicological Concern (TTC) and its exclusions in the biocompatibility assessment of extractable chemical substances from medical devices
<p>Data supporting manuscript Patlewicz G, Nelms M, Rua D. Evaluating the utility of the Threshold of Toxicological Concern (TTC) and its exclusions in the biocompatibility assessment of extractable chemical substances from medical devices. Computational Toxicology, 2022, in press <a href="https://doi.org/10.1016/j.comtox.2022.100246" rel="nofollow">https://doi.org/10.1016/j.comtox.2022.100246</a></p>
Toward Understanding Drug Incorporation and Delivery from Biocompatible Metal-Organic Frameworks in View of Cutaneous Administration
<p>Although metal−organic frameworks (MOFs) have widely<br> demonstrated their convenient performances as drug-delivery systems, there is<br> still work to do to fully understand the drug incorporation/delivery processes<br> from these materials. In this work, a combined experimental and<br> computational investigation of the main structural and physicochemical<br> parameters driving drug adsorption/desorption kinetics was carried out. Two<br> model drugs (aspirin and ibuprofen) and three water-stable, biocompatible<br> MOFs (MIL-100(Fe), UiO-66(Zr), and MIL-127(Fe)) have been selected to<br> obtain a variety of drug−matrix couples with different structural and<br> physicochemical characteristics. This study evidenced that the drug-loading<br> and drug-delivery processes are mainly governed by structural parameters<br> (accessibility of the framework and drug volume) as well as the MOF/drug<br> hydrophobic/hydrophilic balance. As a result, the delivery of the drug under<br> simulated cutaneous conditions (aqueous media at 37 °C) demonstrated that<br> these systems fulfill the requirements to be used as topical drug-delivery systems, such as released payload between 1 and 7 days.<br> These results highlight the importance of the rational selection of MOFs, evidencing the effect of geometrical and chemical<br> parameters of both the MOF and the drug on the drug adsorption and release.</p>
Efficiency and Biocompatibility in Hemodiafiltration Procedure
ClinicalTrials.gov study NCT06807905. IPD Sharing: YES. Countries: 1. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.