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7 results for “biofilm dispersal”
Data from: eDNA-stimulated cell dispersion from Caulobacter crescentus biofilms upon oxygen limitation is dependent on a toxin-antitoxin system
<p><span>In their natural environment, most bacteria preferentially live as complex surface-attached multicellular colonies called biofilms. Biofilms begin with a few cells adhering to a surface, where they multiply to form a mature colony. When conditions deteriorate, cells can leave the biofilm. This dispersion is thought to be an important process that modifies the overall biofilm architecture and that promotes colonization of new environments. In <em>Caulobacter crescentus</em> biofilms, extracellular DNA (eDNA) is released upon cell death and prevents newborn cells from joining the established biofilm. Thus, eDNA promotes the dispersal of newborn cells and the subsequent colonization of new environments. These observations suggest that eDNA is a cue for sensing detrimental environmental conditions in the biofilm. Here we show that </span><span>the toxin-antitoxin system (TAS) <em>ParDE<sub>4</sub></em> stimulates cell death in areas of a biofilm with decreased O<sub>2</sub> availability. In conditions where O<sub>2</sub> availability is low, eDNA concentration is correlated with cell death. Cell dispersal away from biofilms is decreased when <em>parDE<sub>4</sub></em> is deleted, probably due to the lower local eDNA concentration. Expression of <em>parDE<sub>4</sub></em> is positively regulated by O<sub>2</sub> and the expression of this operon is decreased in biofilms where O<sub>2</sub> availability is low. Thus, a programmed cell death mechanism using an O<sub>2</sub>-regulated TAS stimulates dispersal away from areas of a biofilm with decreased O<sub>2</sub> availability and favors colonization of a new, more hospitable environment. </span></p>
Data from: eDNA-stimulated cell dispersion from Caulobacter crescentus biofilms upon oxygen limitation is dependent on a toxin-antitoxin system
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Confocal microscopy images for: Surface remodeling and inversion of cell-matrix interactions underlie community recognition and dispersal in Vibrio cholerae biofilms
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Global transcriptional changes during S. mutans biofilm dispersal
GEO Series GSE95377. Streptococcus mutans. 6 samples. Type: Expression profiling by array.
Stay or Go: Sulfolobales Biofilm Dispersal is Dependent on a Bifunctional VapB Antitoxin
GEO Series GSE226483. Sulfolobus acidocaldarius; Sulfolobus acidocaldarius DSM 639. 4 samples. Type: Expression profiling by array.
Transcriptional profiling of Klebsiella pneumoniae defines signatures for planktonic, sessile and biofilm-dispersed cells
GEO Series GSE71754. Klebsiella pneumoniae. 15 samples. Type: Expression profiling by high throughput sequencing.
Biofilm dispersal of Hha13D6 vs. Hha and biofilm formation of Hha24E9 vs. Hha in E.coli K-12 BW25113 hha mutant in LBglu at 37oC
GEO Series GSE21604. Escherichia coli; Escherichia coli K-12. 4 samples. Type: Expression profiling by array.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.