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819 results for “bipolar disorder”
Examining the Effect of EEG-guided Theta Burst Stimulation in Bipolar Disorder
ClinicalTrials.gov study NCT05179785. IPD Sharing: YES. Countries: 1. Publications: 1.
Improving Adherence in Adolescents and Young Adults With Bipolar Disorder
ClinicalTrials.gov study NCT04348604. IPD Sharing: YES. Countries: 1. Publications: 1.
Alzheimer's Disease versus Bipolar Disorder versus Health Control MRI data and processed results
<p><strong>README</strong></p> <p>The data is structured as follows:</p> <p>Clinical_data folder contains the .csv that can be read by spreadsheet software, as well as from Python, Matlab or R. There are separate files for each biomarker. The file "clinical_data_id_age_gender.csv" contains the numerical random key of the patient for anonymity, diagnostic key, age and gender for each entry in the other files. The file "clinical_data_corrected.csv" can be ignored.</p> <p>Diagnostic keywords: "crl" == healthy control, "tb" == bipolar disorder, "ea" == Alheimer's disease</p> <p>Imaging data is nifti encoded. The name of the file starts with the diagnostic key followed by the numerical random key and some nemotechnic for the contents. For instance: "crl_132_diff_dti_FA_FA_to_target.nii.gz" is the spatially normalized FA data of healthy control 132. Imaging data can be read with FSL, SPM, and any other nifti reading soft.</p> <p>Imaging folders contain the following data<br> DWI_origin - > the original diffusion weighted MRI data and their corresponding b-vector values</p> <p>FA - > the FA coefficients computed using FSL</p> <p>FA_to_target - > the FA volumes registered to MNI template using FSL tools</p> <p>T1_preprocessed - > the T1-weighted volumes at 1mm resolution registered to the MNI template using FSL no-linear registration tools</p> <p>T1_VBM_SPM_1mm - > the results of applying SPM implementation of voxel based morphometry (VBM) on the T1-weighted data, including results of the correlation between biomarkers and the detected clusters . Results can be checked using SPM (https://www.fil.ion.ucl.ac.uk/spm/)</p> <p>TBSS_results -> contains track based spatial statistics (TBSS) results obtained with FSL software (https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/TBSS)</p> <p> </p> <p><strong>Publications using this dataset</strong></p> <p>M. Graña, M. Termenon, A. Savio, A. Gonzalez-Pinto, J. Echeveste, J. M. Pérez, A. Besga, Computer Aided Diagnosis system for Alzheimer Disease using brain Diffusion Tensor Imaging features selected by Pearson’s correlation, Neuroscience letters,Volume 502, Issue 3, 20 September 2011, Pages 225-229</p> <p>A. Besga, M. Termenon, M. Graña, J. Echeveste, J. M. Perez, A. Gonzalez-Pinto "Discovering Alzheimer's disease and bipolar disorder white matter effects building computer aided diagnostic systems on brain diffusion tensor imaging features, <strong>Neuroscience Letters</strong>, Volume 520, Issue 1, 27 June 2012, Pages 71–76.</p> <p>M. Termenon, M. Graña, A. Besga, J. Echeveste, A. Gonzalez-Pinto, Lattice Independent Component Analysis feature selection on Diffusion Weighted Imaging for Alzheimer’s Disease Classification, Neurocomputing (2013) Volume 114, 19 August 2013, Pages 132–141</p> <p>Ariadna Besga, Itxaso González-Ortega, Enrique Echeburúa, Alexandre Savio, Borja Ayerdi, Darya Chyzhyk, Jose LM Madrigal, Juan C. Leza, Manuel Graña, Ana González-Pinto, "Discrimination between Alzheimer’s Disease and Late Onset Bipolar Disorder using multivariate analysis" Frontiers in Aging Neuroscience, 7:231</p> <p>Ariadna Besga-Basterra, Darya Chyzhyk, Itxaso González-Ortega, Alexandre Savio, Borja Ayerdi, Jon Echeveste, Manuel Graña, Ana González-Pinto, Eigenanatomy on fractional anisotropy imaging provides white matter anatomical features discriminating between Alzheimer’s Disease and Late Onset Bipolar Disorder, Current Alzheimer Research, 13(5): 557 - 565 (2016)</p> <p>Ariadna Besga, Darya Chyzhyk, Itxaso Gonzalez Ortega, Jon Echeveste, Marina Grana-Lecuona, Manuel Grana, Ana González-Pinto, White Matter Tract Integrity in Alzheimer’s Disease versus Late Onset Bipolar Disorder and its Correlation with Systemic Inflammation and Oxidative Stress Biomarkers, Frontiers in Aging Neuroscience, 9:179 (2017)</p>
Different patterns of white matter microstructural alterations between psychotic and non-psychotic bipolar disorder
<p><span>This study aimed to investigate alterations in white matter microstructure in </span><span>patients with</span><span> psychotic and non-psychotic bipolar disorder (PBD and NPBD, respectively). We used 3T-magnetic resonance imaging to examine 29 PBD, 23 NPBD, and 65 healthy control (HC) subjects. Using tract-based spatial statistics for diffusion tensor imaging data, we compared fractional anisotropy and mean diffusion pairwise among the PBD, NPBD, and HC groups. </span><span>W</span><span>e found several white matter areas of decreased fractional anisotropy or increased mean diffusion in the PBD and NPBD groups compared to HC. PBD showed widespread fractional anisotropy decreases in the corpus callosum as well as the bilateral internal capsule and fornix. However, NPBD showed local fractional anisotropy decreases in a part of the corpus callosum body as well as in limited regions within the left cerebral hemisphere, including the anterior and posterior corona radiata and the cingulum. In addition, both PBD and NPBD shared widespread mean diffusion increases across the posterior corona radiata, cingulum, and sagittal stratum. These findings suggest that </span><span>widespread </span><span>white matter microstructural alterations might be a common neuroanatomical characteristic of </span><span>bipolar disorder</span><span>, regardless of being psychotic or non-psychotic. Particularly, PBD might involve extensive inter-and intra-hemispheric white matter connectivity disruptions.</span></p>
Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
ClinicalTrials.gov study NCT03187769. IPD Sharing: NO. Countries: 12. Publications: 1.
Treatment to Enhance Cognition in Bipolar Disorder
ClinicalTrials.gov study NCT01470781. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents
ClinicalTrials.gov study NCT06920940. IPD Sharing: YES. Countries: 1. Publications: 13.
A Randomized Controlled Trial of Cognitive Remediation and D-cycloserine for Individuals With Bipolar Disorder
ClinicalTrials.gov study NCT01934972. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effectiveness of Lithium Plus Optimized Medication in Treating People With Bipolar Disorder
ClinicalTrials.gov study NCT00667745. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Light Therapy for Bipolar Disorder. Efficacy of Light Therapy for Bipolar Depression: A Randomized Controlled Trial
ClinicalTrials.gov study NCT00852592. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Lamictal as Add-on Treatment for Bipolar I Disorder in Pediatric Patients
ClinicalTrials.gov study NCT00723450. IPD Sharing: YES. Countries: 1. Publications: 1.
Prediction of Clinical Response to SSRI Treatment in Bipolar Disorder Using Serotonin 1A Receptor PET Imaging
ClinicalTrials.gov study NCT02473250. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Acute Alcohol Response In Bipolar Disorder: a fMRI Study
ClinicalTrials.gov study NCT04063384. IPD Sharing: YES. Countries: 1. Publications: 4.
Sensoril(Ashwaganhda)for Bipolar Disorder
ClinicalTrials.gov study NCT00761761. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Seeing the Light: Early Intervention in People at Risk for Bipolar Disorder
ClinicalTrials.gov study NCT06282250. IPD Sharing: YES. Countries: 1. Publications: 1.
Quetiapine Fumarate (SEROQUEL) in the Treatment of Adolescent Patients With Schizophrenia and Bipolar I Disorder
ClinicalTrials.gov study NCT00227305. IPD Sharing: Not stated. Countries: 9. Publications: 1.
Safety and Efficacy of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed)
ClinicalTrials.gov study NCT00257166. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Riluzole to Treat Depression in Bipolar Disorder
ClinicalTrials.gov study NCT00054704. IPD Sharing: NO. Countries: 1. Publications: 5.
Lithium and Divalproex for the Treatment of Comorbid Rapid Cycling Bipolar Disorder and Substance Abuse Disorder
ClinicalTrials.gov study NCT00194129. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Bipolar Disorder Integrative Staging: Incorporating Biomarkers Into Progression Across Stages
ClinicalTrials.gov study NCT07343739. IPD Sharing: NO. Countries: 1. Publications: 10.
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OpenNeuro
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