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126 results for “blood markers”
Patient reported outcome measures, load-induced blood marker kinetics, and ambulatory knee load in patients with medial compartment knee osteoarthritis
<p>The goal of this study was (i) to quantify the mechanoresponse of this array of potential blood markers for joint pathology (COMP, MMP-1, MMP-3, MMP-9, CPII, C2C, C2C/CPII, ADAMTS-4, PRG-4, IL-6 and resistin) to a walking stress test in patients with knee OA and to determine the correlation (ii) among the kinetics of these blood markers, (iii) with accumulated knee load during the walking stress, and (iv) with patient reported osteoarthritis outcome and QoL.</p> <p>The dataset includes 24 patients with knee osteoarthritis scheduled to receive high tibial osteotomy. All participants completed questionnaires, and a walking stress test with six blood samples analyzed using enzyme-linked immunosorbent assays for cartilage oligomeric matrix protein (COMP), matrix metalloproteinases (MMP)-1, -3, and -9, epitope resulting from cleavage of type II collagen by collagenases (C2C), type II procollagen (CPII), interleukin (IL)-6, proteoglycan (PRG)-4, A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-4, and resistin, and gait analysis. Joint load was computed from gait analysis data and musculoskeletal modelling in AnyBody Modeling System (AnyBody Technology A/S). Discrete loading parameters were extracted for each step using an inhouse algorithm written in Matlab.</p> <p>The detailed experimental protocol of the umbrella study has been described in Mündermann A, Vach W, Pagenstert G, Egloff C, Nüesch C. Assessing in vivo articular cartilage mechanosensitivity as outcome of high tibial osteotomy in patients with medial compartment osteoarthritis: Experimental protocol. Osteoarthr Cartil Open. 2020 Feb 24;2(2):100043. doi: 10.1016/j.ocarto.2020.100043. PMID: 36474590; PMCID: PMC9718245. The study is registered on clinicaltrials.gov (identifier NCT02622204). The method for computing joint loading has been described in detail in De Pieri E, Nüesch C, Pagenstert G, Viehweger E, Egloff C, Mündermann A. High tibial osteotomy effectively redistributes compressive knee loads during walking. J Orthop Res. 2022 Jun 22. doi: 10.1002/jor.25403. Epub ahead of print. PMID: 35730475.</p>
Nutrigenetic Intervention on Blood Lipid Markers and Body Composition of Adults With Overweight and Obesity
ClinicalTrials.gov study NCT05210023. IPD Sharing: NO. Countries: 1. Publications: 9.
................................................................................................................................................. Fig. 3. SDSPAGE analysis of total bacterial protein extracts of the four roe deer isolates as well as other Bartonella species. Extracts of total bacterial protein were separated by SDSPAGE and stained with Coomassie brilliant blue. Lanes: M, molecular mass markers; 1, R1T; 2, R3; 3, R4; 4, R6; 5, Bartonella henselae; 6, Bartonella quintana; 7, Bartonella bacilliformis; 8, Bartonella elizabethae; 9, Bartonella clarridgeiae; 10, Bartonella alsatica; 11, Bartonella tribocorum; 12, Bartonella grahamii. in Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer.
................................................................................................................................................. Fig. 3. SDSPAGE analysis of total bacterial protein extracts of the four roe deer isolates as well as other Bartonella species. Extracts of total bacterial protein were separated by SDSPAGE and stained with Coomassie brilliant blue. Lanes: M, molecular mass markers; 1, R1T; 2, R3; 3, R4; 4, R6; 5, Bartonella henselae; 6, Bartonella quintana; 7, Bartonella bacilliformis; 8, Bartonella elizabethae; 9, Bartonella clarridgeiae; 10, Bartonella alsatica; 11, Bartonella tribocorum; 12, Bartonella grahamii.
"Peripheral Blood Dipeptidylpeptidase IV (CD26) Positive Leukemic Stem Cells in Chronic Myeloid Leukemia as a Diagnostic Marker"
ClinicalTrials.gov study NCT05543161. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Identification of Individual Histological and Blood Markers in Patients With Recurrent or Metastatic Upper Aerodigestive Tract Squamous Cell Carcinoma in Response to Immunotherapies
ClinicalTrials.gov study NCT06061705. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Identification Of Blood Markers For Asymptomatic Ventricular Dysfunction
ClinicalTrials.gov study NCT01024049. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Stroke Risk Assessment and Markers of Blood Clotting in Patients With Newly Diagnosed Non-valvular Atrial Fibrillation (NVAF), Who Have Not Received Oral Anticoagulation Therapy (OAC-therapy) Prior to
ClinicalTrials.gov study NCT06949319. IPD Sharing: UNDECIDED. Countries: 1. Publications: 8.
Analysis of Circulating Tumor Markers in the Blood (ALCINA)
ClinicalTrials.gov study NCT02866149. IPD Sharing: YES. Countries: 1. Publications: 6.
Study of Blood Components as Probable Prognostic and Predictive Markers of Response to Treatment in Advanced Colon and Rectal Cancers
ClinicalTrials.gov study NCT02979470. IPD Sharing: NO. Countries: 1. Publications: 2.
Chromogranin A as Blood Marker in Cancer Patients
ClinicalTrials.gov study NCT03817866. IPD Sharing: NO. Countries: 2. Publications: 1.
Markers of Oxidative Stress Present in Blood in Patients With Atrial Fibrillation
ClinicalTrials.gov study NCT00142194. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Blood Markers in Adult Patients With Sudden Sensorineural Hearing Loss (SSNHL)
ClinicalTrials.gov study NCT03919474. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
HEARTBiT: Multi-Marker Blood Test for Acute Cardiac Transplant Rejection
ClinicalTrials.gov study NCT03575910. IPD Sharing: UNDECIDED. Countries: 2. Publications: 12.
Blood Markers of Inflammation, Blood Clotting and Blood Vessel Function in HIV-infected Adults
ClinicalTrials.gov study NCT00776412. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
NP001, Alzheimer's Disease, and Blood Markers of Inflammation
ClinicalTrials.gov study NCT03179501. IPD Sharing: NO. Countries: 1. Publications: 4.
A Study of a Blood Marker in Newborns With Brain Injury Caused by Lack of Oxygen at Birth
ClinicalTrials.gov study NCT07292220. IPD Sharing: YES. Countries: 1. Publications: 6.
Inflammatory and Cerebrospinal Biochemical Markers in Blood During Prolonged Hyperbaric Exposure
ClinicalTrials.gov study NCT03192930. IPD Sharing: NO. Countries: 1. Publications: 1.
Monitoring Radiation Induced Cardiac Damage by Blood Markers
ClinicalTrials.gov study NCT02481778. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Blood Markers for Identifying & Investigating Infection With COVID19 & Sepsis in Children.
ClinicalTrials.gov study NCT04904523. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants
ClinicalTrials.gov study NCT01439048. IPD Sharing: Not stated. Countries: 1. Publications: 12.
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OpenNeuro
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