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24 results for “brain-derived neurotrophic factor”
Brain-Derived Neurotrophic Factor and extracellular vesicle-derived miRNAs in an Italian cohort of individuals with obesity: a key to explain the link between depression and atherothrombosis.
<p>This record contains raw data related to the article “Brain-Derived Neurotrophic Factor and Extracellular Vesicle-Derived miRNAs in an Italian Cohort of Individuals With Obesity: A Key to Explain the Link Between Depression and Atherothrombosis” </p> <p><em><strong>Abstract: </strong></em></p> <p><strong>Background</strong>: Obesity and depression are intertwined diseases often associated with an increased risk of cardiovascular (CV) complications. Brain-Derived Neurotrophic Factor (BDNF), altered in the brain both of subjects with depression and obesity, provides a potential link between depression and thrombosis. Since the relationship among peripheral BDNF, depression and obesity is not well-defined, the aim of the present report has been to address this issue taking advantage of the contribution played by extracellular vesicle (EV)-derived miRNAs. <strong>Research Process</strong>: Associations among circulating BDNF, depression and EVderived miRNAs related to atherothrombosis have been evaluated in a large Italian cohort of obese individuals (n = 743), characterized by the Beck Depression Inventory (BDI-II) score.<br> <strong>Results</strong>: BDI-II was negatively associated with BDNF levels without a significant impact of the rs6265 BDNF polymorphism; this association was modified by raised levels of IFN-g. BDNF levels were linked to an increase of 80 EV-derived miRNAs and a decrease of 59 miRNAs related to atherosclerosis and thrombosis. Network analysis identified at least 18 genes targeted by these miRNAs, 7 of which involved in depression and CV<br> risk. The observation of a possible link among BDNF, depression, and miRNAs related to atherothrombosis and depression in obesity is novel and may lead to a wider use of BDNF as a CV risk biomarker in this specific subject group.</p>
Effect of Salmeterol on Brain-Derived Neurotrophic Factor (BDNF) Concentrations in Asthma
ClinicalTrials.gov study NCT00736801. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Anti-Platelet Drugs and Brain-derived Neurotrophic Factor (BDNF) in Human Serum and Plasma
ClinicalTrials.gov study NCT01264640. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Kinetics of Plasma and Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) in Patients With Ischemic Stroke
ClinicalTrials.gov study NCT02860260. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Brain-Derived Neurotrophic Factor in Obesity and Brain Function
ClinicalTrials.gov study NCT01517048. IPD Sharing: Not stated. Countries: 2. Publications: 4.
Brain-derived Neurotrophic Factor (BDNF) Single Nucleotide Gene Polymorphism and Nerve Growth Factor as Risk Factors That Increase Severity of Allergic Rhinitis
ClinicalTrials.gov study NCT05907733. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Effects of Aerobic Exercise on Cognitive Function and Brain-derived Neurotrophic Factor in Young Adults
ClinicalTrials.gov study NCT02075944. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Lithium and Divalproex'on Brain-Derived Neurotrophic Factor in Huntington's Disease
ClinicalTrials.gov study NCT00095355. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Investigating the Role of Brain-derived Neurotrophic Factor (BDNF) Between Pain and Other Neuronal Disease
ClinicalTrials.gov study NCT03606915. IPD Sharing: NO. Countries: 1. Publications: 0.
Walking Exercise on Memory, Subjective Cognitive Complaint, and Brain-derived Neurotrophic Factor for Hypertension
ClinicalTrials.gov study NCT04930263. IPD Sharing: NO. Countries: 1. Publications: 0.
Effects of Low-intensity Transcranial Magnetic Stimulation on Major Depressive Disorder, and on 5-hydroxyindoleacetic Acid and Brain-derived Neurotrophic Factor Levels
ClinicalTrials.gov study NCT06667180. IPD Sharing: NO. Countries: 1. Publications: 0.
Müller glia-mediated protection of retinal ganglion cells from ethambutol-induced neurotoxicity through brain-derived neurotrophic factor
GEO Series GSE294687. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Daily Fluctuations in Brain-Derived Neurotrophic Factor and Cognition: Effects of Vigorous Exercise
ClinicalTrials.gov study NCT07385118. IPD Sharing: NO. Countries: 1. Publications: 0.
Brain-derived Neurotrophic Factor and Cogntive Function
ClinicalTrials.gov study NCT01390688. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Acute Effect of Different Resistance Exercise Loads on Irisin and Brain-derived Neurotrophic Factor in Blood Serum and Plasma
ClinicalTrials.gov study NCT07189130. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria
ClinicalTrials.gov study NCT06901323. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor
ClinicalTrials.gov study NCT06040905. IPD Sharing: NO. Countries: 1. Publications: 0.
Does TMS Affect Neuroplasticity? The Role of Brain-derived Neurotrophic Factor and Neuronal Cell Adhesion Molecules - an Intensive Clinical Protocol Among Patients With Obsessive-compulsive Disorders
ClinicalTrials.gov study NCT06231095. IPD Sharing: NO. Countries: 1. Publications: 0.
The Relationship Between Serum S100B and Brain-Derived Neurotrophic Factor
ClinicalTrials.gov study NCT07358754. IPD Sharing: NO. Countries: 0. Publications: 0.
Brain-derived Neurotrophic Factor and the Antidepressant Efficacy of Brain Stimulation
ClinicalTrials.gov study NCT04076124. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.