Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
18
datasets available to search
ShareScore release 0.9.0
Dataset results
18 results for “bystander effect”
Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).
ClinicalTrials.gov study NCT02007499. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Figure 2 in Radiation tolerance and bystander effects in the eutardigrade species Hypsibius dujardini (Parachaela: Hypsibiidae)
Figure 2. Radiation and radiation-induced bystander effects on the eutardigrade species Hypsibius dujardini. Survivorship curves following direct (RAD) and indirect (BYST) exposure to 3 and 5 kGy gamma radiation.
Figure 1 in Radiation tolerance and bystander effects in the eutardigrade species Hypsibius dujardini (Parachaela: Hypsibiidae)
Figure 1. Experimental set-up for testing radiation tolerance and bystander effects in the eutardigrade species Hypsibius dujardini: control (CON; 0 kGy), irradiated [received 3 kGy (RAD3) and 5 kGy (RAD5) gamma radiation] and bystander [exposed to an individual irradiated at the 3 kGy (BYST3) or 5 kGy (BYST5) level] groups.
Effects of Pepper Gas Exposure in Non-combatant Bystanders.
ClinicalTrials.gov study NCT01922700. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Experimentally Testing the Effectiveness of a Campus-based Bystander Intervention
ClinicalTrials.gov study NCT02083302. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Bystander Model-Based Creative Drama on Empathy and Bullying Intervention in Middle School Students
ClinicalTrials.gov study NCT07098559. IPD Sharing: NO. Countries: 1. Publications: 0.
Radiation-induced bystander effects and gene expression in cells deficient for RAD9
Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of radiation exposure to humans. The mechanism of radiation response includes inter-cellular signaling and intra-cellular communication by which the bystander signal is propagated. Methods: We measured the bystander response to 1Gy a-particle radiation in Mrad9-/- mouse stem cells and H1299shRAD9 cells using chromosomal aberration and micronucleus formation as DNA damage endpoints. In the H1299 model we used whole genome microarray analyses to profile the transcriptome of irradiated and bystander cells. Results: We investigated the role of RAD9 in the bystander response and showed that depletion or mutation of RAD9 had an effect of increasing chromosomal structural damage as well as micronucleus formation in bystander cells. The enhancement of the damage effect correlated strongly with a transcriptomic response in critical pathways. RAD9 depletion affected many pathways in the cell including the UV-MAPK pathway involving p38MAPK members STAT1 and PARP1 at the mRNA levels. There was an overall reduction of RNA biogenesis of gene members of this pathway suggesting that perhaps these signaling pathways do not function optimally after RAD9 depletion. Using network analysis we found there may be differential activation of transcriptional regulators between the irradiated and bystander cells involving the SP1 and NUPR1 transcription factors. Network analysis also suggested that HIF1a (Hypoxia induced factor 1a) activation could be a negative predictor of the bystander effect and perhaps that local hypoxic stress observed by cells that are directly exposed to radiation may predict whether or not they will elicit a bystander response. Gene expression in H1299 cells was measured at 4 hours after exposure to 1 Gy a-particles. There were two groups based on RAD9 status RAD9 normal and RAD9 depleted by siRNA. In each of these groups sham irradiated direct irradiated cells for positive bystanders positive bystanders direct irradiated cells for negative bystanders and negative bystanders; were identified based on micronucleus responses. Five biological replicates were analyzed for each experimental group.
Radiation-induced bystander effects and gene expression in cells deficient for RAD9
GEO Series GSE55869. Homo sapiens. 50 samples. Type: Expression profiling by array.
Transcriptional profiling reveals differential effect of in vivo porcine reproductive and respiratory syndrome virus infection on infected and bystander pulmonary alveolar macrophage cells
GEO Series GSE174494. Sus scrofa. 9 samples. Type: Expression profiling by high throughput sequencing.
Radiation-induced bystander effect impaired human hematopoietic stem cells by oxidative DNA damage
GEO Series GSE149649. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Biphasic Effects of Acute Alcohol Intoxication on Bystander Intervention
ClinicalTrials.gov study NCT05701865. IPD Sharing: YES. Countries: 1. Publications: 0.
Effects of Dating Violence Education Program on Bystanders' Help-giving Intention and Behavior Among College Students
ClinicalTrials.gov study NCT05564000. IPD Sharing: NO. Countries: 1. Publications: 0.
Normal human fibroblast cell line bystander effects by Carbon ion irradiation
GEO Series GSE8993. Homo sapiens. 36 samples. Type: Expression profiling by array.
Genome-wide microarray analysis of immortalized human fibroblasts in response to alpha-particle radiation and the radiation induced bystander effect
GEO Series GSE32091. Homo sapiens. 42 samples. Type: Expression profiling by array.
The effect of Ndufa5 expression on bystander cells cultured in conditioned media of chemotherapy-induced senescent cells
GEO Series GSE305033. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
The effect of NDUFA5 expression on bystander cells cultured in conditioned media of chemotherapy-induced senescent cells
GEO Series GSE305002. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide microarray analysis of normal human fibroblasts in response to γ-radiation and the radiation induced bystander effect
GEO Series GSE25772. Homo sapiens. 44 samples. Type: Expression profiling by array.
A novel bystander effect in tamoxifen treatment: PPIB derived from ER+ cells attenuates ER- cells via endoplasmic reticulum stress-induced apoptosis
GEO Series GSE247920. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.