Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
14
datasets available to search
ShareScore release 0.9.0
Dataset results
14 results for “cDNA library”
Data from: Characterization of leukemia-inducing genes using a proto-oncogene/homeobox gene retroviral human cDNA library in a mouse in vivo model
The purpose of this research is to develop a method to screen a large number of potential driver mutations of acute myeloid leukemia (AML) using a retroviral cDNA library and murine bone marrow transduction-transplantation system. As a proof-of-concept, murine bone marrow (BM) cells were transduced with a retroviral cDNA library encoding well-characterized oncogenes and homeobox genes, and the virus-transduced cells were transplanted into lethally irradiated mice. The proto-oncogenes responsible for leukemia initiation were identified by PCR amplification of cDNA inserts from genomic DNA isolated from leukemic cells. In an initial screen of ten leukemic mice, the MYC proto-oncogene was detected in all the leukemic mice. Of ten leukemic mice, 3 (30%) had MYC as the only transgene, and seven mice (70%) had additional proto-oncogene inserts. We repeated the same experiment after removing MYC-related genes from the library to characterize additional leukemia-inducing gene combinations. Our second screen using the MYC-deleted proto-oncogene library confirmed MEIS1and the HOX family as cooperating oncogenes in leukemia pathogenesis. The model system we introduced in this study will be valuable in functionally screening novel combinations of genes for leukemogenic potential in vivo, and the system will help in the discovery of new targets for leukemia therapy.
Data from: Characterization of leukemia-inducing genes using a proto-oncogene/homeobox gene retroviral human cDNA library in a mouse in vivo model
Open the record for dataset details and reuse information.
A novel NGS-based method can improve the efficiency and sensitivity of Y2H screening with cDNA library
GEO Series GSE179488. Arabidopsis thaliana. 9 samples. Type: Other.
Single cell RNA-seq data of human hESCs comparing experiments with cDNA library equalization
GEO Series GSE156494. Homo sapiens. 288 samples. Type: Expression profiling by high throughput sequencing.
Deep sequencing of small RNAs and degradome cDNA library in soybean
GEO Series GSE33380. Glycine max. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
A non-radioactive, improved PAR-CLIP and small RNA cDNA library preparation protocol
GEO Series GSE163925. Homo sapiens. 21 samples. Type: Other.
Hybridization of human oocyte cDNA library on the multi-species oocyte array to assess for gene conservation using a temperature stringency criteria
GEO Series GSE23963. Xenopus laevis; Bos taurus; Mus musculus; Homo sapiens. 6 samples. Type: Expression profiling by array.
Sequencing of First-strand cDNA Library Reveals Full-length Transcriptomes
GEO Series GSE63424. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Repertoire of miRNAs in epithelial ovarian cancer determined by next generation sequencing of small RNA cDNA libraries
GEO Series GSE15190. Homo sapiens. 4 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Deep sequencing of the degradome cDNA library in soybean
GEO Series GSE33379. Glycine max. 1 samples. Type: Expression profiling by high throughput sequencing.
Analysis of a normalised equine cDNA library using deep sequencing
GEO Series GSE26794. Equus caballus. 1 samples. Type: Expression profiling by high throughput sequencing.
Verification of the quality of the retroviral cDNA library composed of 176 proto-oncogenes and HOX genes
GEO Series GSE74806. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Inducible meiotic cDNA libraries for genome-wide studies of gene isoforms
GEO Series GSE174268. Saccharomyces cerevisiae; Escherichia coli. 175 samples. Type: Expression profiling by high throughput sequencing; Other.
Pituitary Tumors cDNA SAGE Libraries
GEO Series GSE37153. Homo sapiens. 4 samples. Type: Expression profiling by SAGE.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.