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ShareScore release 0.9.0
Dataset results
59 results for “cGAS-STING”
Dataset - The cGAS-STING pathway drives type I IFN immunopathology in COVID-19
<p>Dataset corresponding to the LoC studies in the manuscript titled The cGAS-STING pathway drives type I IFN immunopathology in COVID-19. The following data are included:</p> <p>BioEM.zip: Volumetric electron microscopy - representative movies of volumetric scans of fields of view of the vascular face of uninfected control and SARS-CoV-2 infected LoCs. Blender file containing reconstruction of mitochondria.</p> <p>Cleaved-caspase3.zip: Imaris files for analysis of 3D stacks from two- and three-component LoCs immunostained for cleaved-caspase 3.</p> <p>IFN beta.zip: Imaris files for analysis of 3D stacks from two- and three-component LoCs immunostained for IFN beta.</p> <p>PhosphoSTING.zip: Imaris files for analysis of 3D stacks from two component LoCs immunostained for phosphoSTING.</p> <p>Proteomics_R_code.Rmd: Annotated custom scripts in R for the analysis of the proteomics data.</p>
Inhibition of O-GlcNAc transferase activates cGAS-STING pathway
Open the record for dataset details and reuse information.
Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice [mRNA-seq]
GEO Series GSE241577. Mus musculus. 46 samples. Type: Expression profiling by high throughput sequencing.
Manganese (II) Activates cGAS-STING pathway
GEO Series GSE77216. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Microbial infection instigates tau-related pathology in Alzheimer's disease via activating neuroimmune cGAS-STING pathway
GEO Series GSE264504. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
CK1α suppresses autoimmunity by restraining the cGAS-STING signaling
GEO Series GSE226593. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
CytoDNA triggered NP cell inflammatory senescence via cGAS-STING axis sensing but not AIM2 inflammasome activation
GEO Series GSE245147. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic priming improves salvage chemotherapy in diffuse large B-cell lymphoma via endogenous retrovirus-induced cGAS-STING activation
GEO Series GSE190319. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Nuclease CAD restrains cGAS-STING signaling to inhibit radiosensitivity of colorectal cancer
GEO Series GSE283230. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Trabectedin and olaparib combination primes cellular immunotherapy with HLA-independent killer lymphocytes against sarcoma preclinical models through the cGAS-STING pathway
GEO Series GSE239639. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
The effect of inhibiting the cGAS-STING pathway in a chronic liver disease mouse model
GEO Series GSE277012. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
MATRIN3 deficiency leads to cGAS-STING activation
GEO Series GSE216830. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing; Expression profiling by array; Other.
cGAS-STING axis activation drove inflammatory phenotype acquisition of senescent nucleus pulposus cells via p65-mediated transcriptional modulation
GEO Series GSE244403. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Inhibiting macrophage-derived lactate transport restores cGAS-STING signaling and enhances anti-tumour immunity in glioblastoma
GEO Series GSE266884. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Brucellosis Vaccine Ag85a-S2 activates cGAS-Sting Signaling Pathway in Intestinal Mucosal Cells
GEO Series GSE205786. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
OLFM4 is a direct target of the cGAS-STING pathway and acts as an extracellular inhibitor for the Hippo signaling in EBV-associated cancer
GEO Series GSE240274. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin cardiomyopathy mice [SLAM-IT-seq]
GEO Series GSE241589. Mus musculus. 21 samples. Type: Other.
Upregulated c-JUN induces aberrant transposable element mobilization, cGAS-STING activation and cell death in Alzheimer's disease
GEO Series GSE213610. Homo sapiens. 61 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Activation of cGAS-STING signal to inhibit the proliferation of bladder cancer: the immune effect of cisplatin
GEO Series GSE165767. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
OLFM4 is a direct target of the cGAS-STING pathway and acts as an extracellular inhibitor for the Hippo signaling in EBV-associated cancer
GEO Series GSE240275. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.