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141 results for “caloric restriction”
Data for: Caloric restriction extends lifespan in a clonal plant
<p>When subjected to dietary caloric restriction (CR), individual animals often outlive well-fed conspecifics. Here, we address whether CR also extends lifespan in plants. Whereas caloric intake in animals comes from ingestion, in plants it derives from photosynthesis. Thus, factors that reduce photosynthesis, such as reduced light intensity, can induce CR. In two lab experiments investigating the aquatic macrophyte <em>Lemna minor</em>, we tracked hundreds of individuals longitudinally, with light intensity – and hence, CR – manipulated using neutral-density filters. In both experiments, CR dramatically increased lifespan through a process of temporal scaling. Moreover, the magnitude of lifespan extension accorded with the assumptions that (a) light intensity positively relates to photosynthesis following Michaelis-Menten kinetics, and (b) photosynthesis negatively relates to lifespan via a power law. Our results emphasize that CR-mediated lifespan extension applies to autotrophs as well as heterotrophs, and suggest that variation in light intensity has quantitatively predictable effects on plant aging trajectories.</p>
Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease
ClinicalTrials.gov study NCT03342742. IPD Sharing: YES. Countries: 1. Publications: 1.
Data for: Caloric restriction extends lifespan in a clonal plant
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Data from: Caloric restriction-mediated reproductive lifespan extension across multiple strains of the clonal aquatic plant <em>Lemna turionifera</em>
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Supplemental code and data for Hernandez et al. "Maternal effect senescence and caloric restriction interact to affect fitness through changes in life history timing"
<p>This dataset enables the user to repeat the analyses presented in the manuscript "Maternal effect senescence and caloric restriction interact to affect fitness through changes in life history timing." It is comprised of two compressed archives: one which contains code, and one which contains data.</p>
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
ClinicalTrials.gov study NCT02945410. IPD Sharing: NO. Countries: 1. Publications: 19.
Daily Caloric Restriction in ADPKD
ClinicalTrials.gov study NCT04907799. IPD Sharing: YES. Countries: 1. Publications: 3.
The Effect of Ketogenic-caloric Restricted Diet on Metabolic Endotoxemia in Prediabetic Obese Adults
ClinicalTrials.gov study NCT06911879. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Caloric Restriction on Fat Oxidation in Obese Men and Women (Magellan II)
ClinicalTrials.gov study NCT01616082. IPD Sharing: Not stated. Countries: 1. Publications: 19.
Long-term Caloric Restriction and Cellular Aging Markers
ClinicalTrials.gov study NCT01256840. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Caloric Restriction in Treating Patients With Stage 0-I Breast Cancer Undergoing Surgery and Radiation Therapy
ClinicalTrials.gov study NCT01819233. IPD Sharing: Not stated. Countries: 1. Publications: 14.
Prolonged Daily Fasting as a Viable Alternative to Caloric Restriction in At-Risk Obese Humans
ClinicalTrials.gov study NCT04259632. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of a Short Term Caloric Restriction on T Cell Activation in Fat
ClinicalTrials.gov study NCT02473835. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Los
ClinicalTrials.gov study NCT06079658. IPD Sharing: NO. Countries: 1. Publications: 4.
The Combined Effect of Dietary Nitrate and Caloric Restriction on Cognitive and Vascular Function.
ClinicalTrials.gov study NCT06151015. IPD Sharing: YES. Countries: 1. Publications: 7.
Intermittent Fasting, Caloric Restriction and Body Composition in Obese Men and Women
ClinicalTrials.gov study NCT02525419. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Caloric Restriction, Exercise, and Glucoregulation in Humans
ClinicalTrials.gov study NCT00777621. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes Mellitus
ClinicalTrials.gov study NCT01083108. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Effects of Intermittent Caloric Restriction in Youth With Cardiometabolic Risk
ClinicalTrials.gov study NCT04011995. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Caloric Restriction and Insulin Secretion
ClinicalTrials.gov study NCT01447524. IPD Sharing: Not stated. Countries: 1. Publications: 26.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.