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116 results for “cardiac fibrosis”
Impedance Reconstruction of Non-transmural Cardiac Fibrosis
<div>In this dataset we can find geometrical setups that served as an input to carry simulations with openCARP and EIDORS. The setup consists of a Lasso with point electrodes placed on patch of tissue and embedded in a box of blood. The tissue simulates a myocardium that can be either fully healthy, fully scarred, or healthy with a 8-mm width line of scar tissue.</div> <div>In addition, the voltage and local impedance maps obtained as results are included.</div> <div>Two kinds of simulations were performed: reconstruction the forward injection of a 5µA current at 14.6kHz with EIDORS, and the electrical wave propagation with openCARP.</div> <div>For the impedance reconstruction, a four electrode circuit was always used, meaning that two electrodes were part of the injecting pattern and a potential difference was measured between another two. The stimulating pair were sequentially changed among all pairs of neighbouring electrodes, whereas the rest of them contributed to the measurement.</div> <div>The voltage maps were computed taking the recovered EGMs from the electrode positions.</div> <div> </div> <h2>Data structure</h2> <div> <ul> <li>inputGeometries: 24 vtk files representing the input setup for simulations. The file names are of the form imageXX_append_cleanToGrid_LOCATION, where XX is a number among 06, 11, 52, and 55, and LOCATION refers to the position in z-axis (transmural, endo-, midmyo-, epicardio).</li> </ul> </div> <div> <ul> <li>results: <ul> <li>BidomainSimulations: the extracellular potentials of each electrical propagation simulation using the Courtemanche model are saved in each of the 16 folders. All the corresponding outputs from a pseudobidomain openCARP simulation are located in each folder. <ul> <li>2023-04-16_image06_endo_00</li> <li>2023-04-16_image06_epi_00</li> <li>2023-04-16_image06_mid_00</li> <li>2023-04-16_image06_transmural_00</li> <li>2023-04-16_image11_endo_00</li> <li>2023-04-16_image11_epi_00</li> <li>2023-04-16_image11_mid_00</li> <li>2023-04-16_image11_transmural_00</li> <li>2023-04-16_image52_endo_00</li> <li>2023-04-16_image52_epi_00</li> <li>2023-04-16_image52_mid_00</li> <li>2023-04-16_image52_transmural_00</li> <li>2023-04-16_image55_endo_00</li> <li>2023-04-16_image55_epi_00</li> <li>2023-04-16_image55_mid_00</li> <li>2023-04-16_image55_transmural_00</li> </ul> </li> <li>ImpedanceSimulations: mat and vtk files corresponding to either local electrical impedance reconstruction simulation. The file names are of the form imageXX_append_cleanToGrid_LOCATION, where XX is a number among 06, 11, 52, and 55, and LOCATION refers to the position in z-axis (transmural, endo-, midmyo-, epicardio). </li> </ul> </li> </ul> </div>
Data for the paper titled 'Dynamic Molecular Atlas for Cardiac Fibrosis at Single-Cell and Spatial Resolution: CD248 in Orchestrating Fibroblast-Immune Interaction'
<p>The deposited data were employed to generate the figures concerning single-cell RNA (scRNA) and spatial transcriptomic analyses in the paper titled 'Dynamic Molecular Atlas for Cardiac Fibrosis at Single-Cell and Spatial Resolution: CD248 in Orchestrating Fibroblast-Immune Interaction'.</p>
Effects of SGLT-2 Inhibition on Myocardial Fibrosis and Inflammation as Assessed by Cardiac MRI in Patients With DM2
ClinicalTrials.gov study NCT03782259. IPD Sharing: Not stated. Countries: 1. Publications: 3.
MKP5 deficiency protects against pressure overload-induced cardiac hypertrophy and fibrosis
Open the record for dataset details and reuse information.
the Role of cArdiac Inflammation, endoThelial Dysfunction, and FIbrosis in fabrY Disease
ClinicalTrials.gov study NCT06776419. IPD Sharing: NO. Countries: 1. Publications: 27.
Cardiac Structure and Function in Patients with Cystic Fibrosis
ClinicalTrials.gov study NCT06084468. IPD Sharing: UNDECIDED. Countries: 1. Publications: 13.
Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency
ClinicalTrials.gov study NCT05317806. IPD Sharing: YES. Countries: 1. Publications: 36.
Molecular Imaging of Myocardial Fibrosis in Cardiac Amyloidosis
ClinicalTrials.gov study NCT05619302. IPD Sharing: NO. Countries: 1. Publications: 3.
Characterization of Myocardial Interstitial Fibrosis and Cardiomyocyte Hypertrophy by Cardiac MRI in Heart Failure
ClinicalTrials.gov study NCT03084679. IPD Sharing: NO. Countries: 1. Publications: 43.
The Effect of Angiotensin Receptor-Neprilysin Inhibition on Cardiac Fibrosis in Patients With HFpEF
ClinicalTrials.gov study NCT05089539. IPD Sharing: NO. Countries: 1. Publications: 3.
Searching for the relationship between the presence, extent, location and 12-month dynamics of cardiac fibrosis and the genetic profile in patients with dilated cardiomyopathy - a pilot study
Open the record for dataset details and reuse information.
Effects of Interval Training Effects on Cardiac Fibrosis
ClinicalTrials.gov study NCT04038723. IPD Sharing: NO. Countries: 0. Publications: 1.
Transcription factor 21 regulates cardiac myofibroblast formation and fibrosis [scRNA-Seq]
GEO Series GSE261150. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction
GEO Series GSE236854. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis II
GEO Series GSE218391. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing; Other.
Roles of circular RNA in cardiac fibrosis
GEO Series GSE240332. Mus musculus. 24 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The role of TMEM43 in cardiac fibrosis and dysfunction
GEO Series GSE147317. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Translational control of cardiac fibrosis (I)
GEO Series GSE123018. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing; Other.
A Porcine Model of Heart Failure With Preserved Ejection Fraction Induced by Chronic Pressure Overload Characterized by Cardiac Fibrosis and Remodeling
GEO Series GSE167643. Sus scrofa. 6 samples. Type: Expression profiling by high throughput sequencing.
Cardiac reprogramming and Gata4 overexpression reduce fibrosis and improve diastolic dysfunction in heart failure with preserved ejection fraction [Visium]
GEO Series GSE218759. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing; Other.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.