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39 results for “carnosine”
Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
ClinicalTrials.gov study NCT00810368. IPD Sharing: NO. Countries: 1. Publications: 5.
Carnosine levels in the same individuals as measured by different modalities
<p>Carnosine is an endogenous di-peptide (b-alanine -L- histidine) involved in maintaining tissue homeostasis. It is most abundant in skeletal muscle where its concentration has been determined in biopsy samples using tandem mass spectrometry (MS-MS). Carnosine levels can also be assessed in intact leg muscles by proton magnetic resonance spectroscopy (1H-MRS) or in blood and urine samples using mass spectrometry. Nevertheless, it remains uncertain how carnosine levels from these distinct compartments are correlated with each other when measured in the same individual. Furthermore, it is unclear which measurement modality might be most suitable for large-scale clinical studies. Hence, in 31 healthy volunteers, we assessed carnosine levels in skeletal muscle, via 1H-MRS, and in erythrocytes and urine by MS-MS. While muscle carnosine levels were higher in males, there was no sex-associated difference in urinary or erythrocyte levels. In a linear regression model adjusted for age, sex, race, and diet, there was a positive association between erythrocyte and urinary carnosine. However, no association was observed between 1H-MRS and erythrocytes or urinary measures. In the relationship between muscle versus urinary and erythrocyte measures, females had a positive association, while males did not show any association. We also found that 1H-MRS measures were highly sensitive to location of measurement. Thus, it is uncertain whether 1H-MRS can accurately and reliably predict endogenous carnosine levels. In contrast, urinary and erythrocyte carnosine measures may be stable and in greater synchrony, and given financial and logistical concerns, may be a feasible alternative for large-scale clinical studies.</p>
Effects of Carnosine In Patients With Peripheral Arterial Disease Patients
ClinicalTrials.gov study NCT06480760. IPD Sharing: NO. Countries: 1. Publications: 39.
The Potential of Carnosine Supplementation in Reducing the Cardiometabolic Risk
ClinicalTrials.gov study NCT02686996. IPD Sharing: NO. Countries: 1. Publications: 1.
Creatine, Carnitine and Carnosine in Vegetarians
ClinicalTrials.gov study NCT03194334. IPD Sharing: NO. Countries: 0. Publications: 2.
Carnosine Supplementation on Quantity/Quality of Oral Salivae.
ClinicalTrials.gov study NCT04295525. IPD Sharing: NO. Countries: 1. Publications: 10.
Polaprezinc (Zinc L-carnosine) in Infants With Gastroesophageal Reflux
ClinicalTrials.gov study NCT06678997. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
L-carnosine for Schizophrenia
ClinicalTrials.gov study NCT00177177. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Carnosine for Peripheral Arterial Disease Patients
ClinicalTrials.gov study NCT05371145. IPD Sharing: NO. Countries: 1. Publications: 10.
Carnosine Supplementation and Cardiovascular Function
ClinicalTrials.gov study NCT05723939. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Efficacy of Zinc L-carnosine in Maintaining Remission of Gastroesophageal Reflux Disease
ClinicalTrials.gov study NCT03467438. IPD Sharing: YES. Countries: 1. Publications: 4.
Oral Carnosine for Neuromuscular Performance in Multiple Sclerosis
ClinicalTrials.gov study NCT03995810. IPD Sharing: YES. Countries: 1. Publications: 2.
The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health
ClinicalTrials.gov study NCT02917928. IPD Sharing: NO. Countries: 1. Publications: 4.
Efficacy of Zinc L-Carnosine Mouth Rinse
ClinicalTrials.gov study NCT04430998. IPD Sharing: NO. Countries: 1. Publications: 5.
Effect of Zinc Carnosine on Intestinal Permeability in Healthy Volunteers
ClinicalTrials.gov study NCT00149149. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Role of Carnosine in Combination With Vitamin B Complex in Preventing the Progression of Diabetic Neuropathy in Type 2 Diabetes Patients
ClinicalTrials.gov study NCT05422352. IPD Sharing: NO. Countries: 1. Publications: 10.
Pharmacokinetics of Carnosine
ClinicalTrials.gov study NCT00721708. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Carnosine levels in the same individuals as measured by different modalities
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Carnosine Loading and Periodized Training in MS and HC
ClinicalTrials.gov study NCT03418376. IPD Sharing: NO. Countries: 1. Publications: 0.
Carnosine Regulation of Intracellular pH Homeostasis Promotes Lysosome-dependent Tumor Immunoevasion
GEO Series GSE198881. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.