Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
12
datasets available to search
ShareScore release 0.9.0
Dataset results
12 results for “causative agents”
Population genetics as a tool to elucidate pathogen reservoirs: Lessons from Pseudogymnoascus destructans, the causative agent of White-Nose disease in bats
<p>Emerging infectious diseases pose a major threat to human, animal, and plant health. The risk of species-extinctions increases when pathogens can survive in the absence of the host. Environmental reservoirs can facilitate this. However, identifying such reservoirs and modes of infection is often highly challenging. In this study, we investigated the presence and nature of an environmental reservoir for the ascomycete fungus <i>Pseudogymnoascus destructans</i>, the causative agent of White-Nose disease. Using 18 microsatellite markers, we determined the genotypic differentiation between 1,497 <i>P. destructans</i> isolates collected from nine closely situated underground sites where bats hibernate (i.e., hibernacula) in Northeastern Germany. This approach was unique in that it ensured that every isolate and resulting multi-locus genotype was not only present, but also viable and therefore theoretically capable of infecting a bat. The distinct distribution of multi-locus genotypes across hibernacula demonstrates that each hibernaculum has an essentially unique fungal population. This would be expected if bats become infected in their hibernaculum (i.e., the site they spend winter in to hibernate) rather than in other sites visited before they start hibernating. In one hibernaculum where both the walls and the hibernating bats were sampled at regular intervals over five consecutive winter seasons (1,062 isolates), higher genotypic richness was found on walls compared to bats and multi-locus genotypes showed a stable frequency over multiple winters. This clearly implicates hibernacula walls as the main environmental reservoir of the pathogen, from which bats become re-infected annually during hibernation.</p>
Transposable prophages in leptospira : an ancient, now diverse, group predominant in causative agents of Weil's disease
<p>The virome associated to the corkscrew shaped bacterium leptospira, responsible for the Weil disease, is scarcely known and genetic tools available for these bacteria remain limited. To reduce these two issues, potential transposable prophages were searched in <em>Leptospiraceae</em> genomes. The 236 predicted transposable prophages are particularly abundant in the most pathogenic leptospiral clade, being potentially involved in the acquisition of virulent traits. According to genomic similarities and phylogenies, these prophages are distantly related to known transposable phages and are organized into six groups, one of them encompassing prophages with unusual TA-TA ends. Interestingly, structural and transposition proteins reconstruct different relationships between groups, suggesting ancestral recombinations. Based on the baseplate phylogeny, two large clades emerge, with specific gene-contents and high sequence divergence reflecting their ancient origin. Despite their high divergence, the size and overall genomic organization of all prophages are very conserved, a testimony of the highly constrained nature of their genomes. Finally, similarities between these prophages and the three known non-transposable phages infecting <em>L. biflexa</em>, suggest gene transfer between different Caudovirales inside their leptospiral host, and the possibility to use some of the transposable prophages in that model strain.</p>
<em>Vibrio pectenicida</em> strain FHCF-3 is a causative agent of sea star wasting disease
Open the record for dataset details and reuse information.
Data from: Molecular and niche modeling approaches to identify potential amplifying hosts for an emerging tick-borne pathogen, Rickettsia rickettsii subsp. californica, the causative agent of Pacific Coast tick fever
Open the record for dataset details and reuse information.
Population genetics as a tool to elucidate pathogen reservoirs: Lessons from Pseudogymnoascus destructans, the causative agent of White-Nose disease in bats
Open the record for dataset details and reuse information.
Figs. 10–12 in New Information About the Cypress Weevil,Eudociminus mannerheimii(Boheman, 1836) (Coleoptera: Curculionidae: Molytinae): Redescription, Range Expansion, New Host Records, and Report as a Possible Causative Agent of Tree Mortality
Figs. 10–12. Tree damage by Eudociminus mannerheimii. 10) Exit holes; 11) Larval galleries after bark was removed; 12A–B) Larva in situ.
Figs. 7–9 in New Information About the Cypress Weevil,Eudociminus mannerheimii(Boheman, 1836) (Coleoptera: Curculionidae: Molytinae): Redescription, Range Expansion, New Host Records, and Report as a Possible Causative Agent of Tree Mortality
Figs. 7–9. Eudociminus mannerheimii, immature stages and landscape damage. 7) Larva; 8) Pupa; 9) Landscape damage. "X" indicates the same tree in both photographs; A) View left showing one undamaged tree and three minimally damaged trees, B) View right showing three minimally damaged trees and two dead trees.
Figs. 1–6 in New Information About the Cypress Weevil,Eudociminus mannerheimii(Boheman, 1836) (Coleoptera: Curculionidae: Molytinae): Redescription, Range Expansion, New Host Records, and Report as a Possible Causative Agent of Tree Mortality
Figs. 1–6. Eudociminus mannerheimii, adults, dorsal (A) and lateral (B) habitus. 1) Steel Creek, Newton Co., Arkansas; 2) "Univ. of Ark. Student Coll."; 3–4) Phelps Lake, North Carolina; 5) Holly Springs, Wake Co., North Carolina; 6) Gainesville, Alachua Co., Florida. Photograph by Michael C. Thomas. Used with permission. Not to scale.
Safety and Immunogenicity of LNP-nCOV saRNA-02 Vaccine Against SARS-CoV-2, the Causative Agent of COVID-19
ClinicalTrials.gov study NCT04934111. IPD Sharing: YES. Countries: 1. Publications: 50.
Proteome annotation of Phytophthora oleae, isolate VK10A, causative agent of rot of olive drupes.
<p>The proteome of Phytophthora oleae, isolate VK10A, causative agent of rot of olive drupes was predicted by using the genomic sequence (AUGUSTUS/GeneMark-ES) as described before (<a href="https://doi.org/10.5281/zenodo.11092245">https://doi.org/10.5281/zenodo.11092245</a>) and <em>de novo</em> mRNA assembly carried out by Trinity and GeneMark. Here, we present the proteome annotation of both genomic CDS and ORF, these latter derived from sense and antisense orientation of <em>de novo</em> mRNA. </p>
Correlative Study on Cancer Patients and Healthcare Professionals Exposed to Infection by Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-Cov-2), COVID-19 Causative Agent.
ClinicalTrials.gov study NCT04345315. IPD Sharing: NO. Countries: 1. Publications: 0.
PRV is the causative agent of HSMI
<p>Data from challenge trial #1 and #2</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.