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141 results for “cerebral artery”
Widefield and Confocal brain images derived from experimental Middle Cerebral Artery occlusion (MCAo) in mice.
<p>This deposit contains a series of widefield and confocal brain images derived from research on cerebral ischemia carried out by the Laboratory of Neurovascular Interactions (https://elalilab.com/) at the Université Laval, Québec (Canada) directed by Dr. Ayman ElAli (<a href="mailto:ayman.el-ali@crchudequebec.ulaval.ca">ayman.el-ali@crchudequebec.ulaval.ca</a>). The experiments, data processing, and organization were performed by Daniel Manrique-Castano, former postdoctoral fellow and current research data curation officer at the Digital Research Alliance of Canada (<a href="https://daniel-manrique.github.io/">https://daniel-manrique.github.io/manrique; </a>dmanriquecastano@gmail.com).</p> <p>Given the complexity of the whole image bundle, images from the same experiment were compressed into zip files. Complementary data is available at the <strong>Open Science Framework (OSF) repository</strong> (<span><a href="https://osf.io/74mqn/" target="_blank" rel="noopener">10.17605/OSF.IO/74MQN</a>), and reproducible workflows for image processing and analysis are available on <strong>GitHub</strong> (<a href="https://doi.org/10.5281/zenodo.13948420" target="_blank" rel="noopener">10.5281/zenodo.13948420</a>)</span></p> <p> </p> <p><strong>Naming conventions for datasets</strong> (taking as an example Widefield_5x_Ipsilateral_KO_CD31-ColIV-Iba1.zip)</p> <p>Widefield: Imaging type performed (available strings = Confocal, Widefield). </p> <p>5x: Objective magnification (Available strings = 5x, 10x, 20x, 40x). </p> <p>Ipsilateral: Iaged region (Available strings = ROIs [Regions of interest], Whole [whole brain], Ipsilateral [ischemic hemisphere]). </p> <p>KO: imaging performed in PDGFRB_KLF4-KO mice (if absent, imaging performed in PDGFRB_TdTomato mice) </p> <p>CD31-ColIV-Iba1: Imaged markers (available strings = multiple, depending on the experiment). </p> <p> </p> <p><strong>Important: </strong>Each .zip file contains a README file specific to each dataset, describing the experimental conditions, naming conventions of individual images and links to additional files used for image processing.</p> <p> </p> <p> </p>
Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
ClinicalTrials.gov study NCT02667821. IPD Sharing: YES. Countries: 1. Publications: 13.
Middle Cerebral Artery Occlusion (MCAO) surgery technique
<p>Middle Cerebral Artery Occlusion (MCAO) surgery performed on 129/Sv mice to model a 35-minutes transient focal cerebral ischemia according to a modified version of the Koizumi method. Silicone resin-coated nylon monofilament (MCAO suture, Doccol Corporation, Cat# 702234PK5Re) is inserted through the common carotid artery (CCC).</p> <p>Contact:</p> <p>danielmanriquecastano@gmail.com</p> <p>Reference:</p> <p>Koizumi J, Yoshida Y, Nakazawa T, Ooneda G. Experimental studies of ischemic brain edema. I: A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area. Jpn J Stroke 1986(8):1–8.</p>
Visualization of Cerebral Arteries Using Contrast-Enhanced Transcranial Ultrasound in Stroke Patients
ClinicalTrials.gov study NCT00282841. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Risk Factors of Middle Cerebral Artery Aneurysm.
ClinicalTrials.gov study NCT03493035. IPD Sharing: YES. Countries: 1. Publications: 8.
Spectrum of cerebral arteriopathies in children with arterial ischaemic stroke
<p><span><b>Objective: </b>To determine that children with arterial ischaemic stroke due to an identifiable arteriopathy are distinct from those without arteriopathy, and that each arteriopathy subtype has unique and recognizable clinical features.</span></p> <p><b>Methods: </b>We report a large, observational, multicenter cohort of children with AIS, age 1-month to 18-years, enrolled into the International Pediatric Stroke Study from 2003 to 2014. Clinical and demographic differences were compared using the Fisher exact test, with linear step-up permutation min-<i>p</i> adjustment for multiple comparisons. Exploratory analyses were conducted to evaluate differences between AIS cases with and without arteriopathy and between arteriopathy subtypes.</p> <p><b>Results: </b>Of 2,127 children with AIS, 725 (34%) had arteriopathy (median age 7.45 years). Arteriopathy subtypes included: dissection (27%), moyamoya (24.5%), focal cerebral arteriopathy–inflammatory subtype (FCA-i, 15%), diffuse cerebral vasculitis (15%), and non-specific arteriopathy (18.5%). Children with arteriopathic AIS were more likely to present between 6-9 years of age (p=0.029, OR 1.93), with headache (p=0.023, OR 1.55), multiple infarctions (p<0.001, OR 2.05), sickle cell anemia (p=0.007, OR 2.9), and head/neck trauma (p=0.018, OR 1.93). Antithrombotic usage and stroke recurrence were higher in children with arteriopathy. Among arteriopathy subtypes, patient with dissection were associated with male sex, older age, headache, and anticoagulant use; FCA-i with hemiparesis and single infarcts; moyamoya with seizures and recurrent strokes; and vasculitis with bilateral infarctions.</p> <p><b>Conclusion: </b>Specific clinical profiles are associated with cerebral arteriopathies in children with AIS. These observations may be helpful indicators in guiding early diagnosis and defining subgroups that may benefit most from future therapeutic trials.</p>
Designing and Comparing Optimized Pseudo-Continuous Arterial Spin Labeling Protocols for Measurement of Cerebral Blood Flow
<p>This repository contains the the simulation data, preprocessed in vivo data, and analysis code used in the NeuroImage article titled 'Designing and Comparing Optimized Pseudo-Continuous Arterial Spin Labeling Protocols for Measurement of Cerebral Blood Flow' (<a href="https://doi.org/10.1016/j.neuroimage.2020.117246">https://doi.org/10.1016/j.neuroimage.2020.117246</a>). Please cite this article if you use this code or data in your work.</p>
rOMT processed data: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries
<p>This dataset contains the speed map and Péclet map data processed by regularized optimal mass transport method (<a href="https://zenodo.org/record/5809635#.YczuJy2ZNBw">https://zenodo.org/record/5809635#.YczuJy2ZNBw</a>, <a href="https://github.com/xinan-nancy-chen/rOMT">https://github.com/xinan-nancy-chen/rOMT</a>).</p> <p>All files are in nifty format. This dataset contains in total 55 rat cases which are divided by age (3-month, 6-month and 12-month) and status of health ("WT" for wild-type and "CAA" for those who have developed Cerebral Amyloid Angiopathy).</p>
Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion
ClinicalTrials.gov study NCT00777140. IPD Sharing: Not stated. Countries: 1. Publications: 17.
The Effect of Nitroglycerin Infusion Rate on Cerebral Rewarming During Hypothermic Coronary Artery Bypass Grafting
ClinicalTrials.gov study NCT03251599. IPD Sharing: NO. Countries: 1. Publications: 5.
Spider Versus Emboshield Distal Protection on Cerebral Microembolization During Vulnerable Plaque in Carotid Artery Stenting
ClinicalTrials.gov study NCT04904250. IPD Sharing: NO. Countries: 1. Publications: 0.
Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion
ClinicalTrials.gov study NCT06221371. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Remote Ischemic Preconditioning on Cerebral Circulation Time in Patients With Severe Carotid Artery Stenosis (RIP-CCT)
ClinicalTrials.gov study NCT05451030. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy:
ClinicalTrials.gov study NCT05842616. IPD Sharing: YES. Countries: 1. Publications: 1.
The Carotid and Middle Cerebral Artery Occlusion Surgery Study
ClinicalTrials.gov study NCT01758614. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Role of the Type of Carotid Stent and Cerebral Protection on Cerebral Microembolization During Carotid Artery Stenting. A Randomized Study Comparing Carotid Wallstent vs Roadsaver® Stent and Distal vs
ClinicalTrials.gov study NCT02915328. IPD Sharing: NO. Countries: 1. Publications: 1.
Stereotactic Infarct Tissue Aspiration for Malignant Infarction of Middle Cerebral Artery
ClinicalTrials.gov study NCT02609256. IPD Sharing: Not stated. Countries: 1. Publications: 8.
The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia
ClinicalTrials.gov study NCT02203097. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Decompressive Craniectomy In Malignant Middle Cerebral Artery Infarcts
ClinicalTrials.gov study NCT00190203. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Autologous Bone Marrow Stem Cells in Middle Cerebral Artery Acute Stroke Treatment.
ClinicalTrials.gov study NCT00761982. IPD Sharing: Not stated. Countries: 1. Publications: 2.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.