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48 results for “chikungunya virus”
CHIKVnext: Molecular epidemiology of Chikungunya virus
<p>CHIKVnext is an interactive resource to study the evolution and global spread of Chikungunya virus (CHIKV), built on the Nextstrain platform.</p>
A Multi-Site Investigation into the Epidemiology of Chikungunya Virus in Neglected Regions of Indonesia
<p>Supporting datasets for phylogenetic analysis of Indonesian chikungunya virus sequences using BEAST v1.10.4.</p> <p> </p>
Molecular and biological characterization of an Asian-American isolate of Chikungunya Virus
<p>This is a dataset of the figures used in the development of the manuscript <strong>Molecular and biological characterization of an Asian-American isolate of Chikungunya Virus</strong></p> <p> </p>
RNA sequences for Aedes species, Dengue, and Chikungunya viruses
<p>There are arthropod-borne disease outbreaks as a result of pathogen influx including arboviruses which are transmitted by strains of <em>Aedes</em> species that occur periodically in varying spots on the globe. The aim of this study was to determine phylogenetic relationship of <em>Aedes</em> mosquitoes, Dengue, and Chikungunya viruses along the Coastline of Kenya based on sequences of:</p> <ol> <li>mitochondria nicotinamide adenine dehydrogenase sub unit 4 gene for Aedes species.</li> <li>non-structural protein 5 gene for Dengue virus</li> <li>non-structural protein 1 gene for Chikungunya virus</li> </ol>
The Aedes aegypti RNA interference response against Zika virus in the context of co-infection with dengue and chikungunya viruses
<p>This is the corresponding data of the Publication in Plos Neglected tropical diseases.</p> <p>Zika virus (ZIKV) is a mosquito-borne human-pathogenic arbovirus of the <em>Flaviviridae</em> family, genus <em>Flavivirus</em>. Other arboviruses, including dengue (DENV) or chikungunya (CHIKV) virus, can occur in the same regions as ZIKV and are also transmitted by <em>Aedes aegypti</em>. Notably, it has been shown that these viruses can co-infect this mosquito, andco-transmission occurs. Such processes may add to the serious public health issues already linked to those pathogens. Arbovirus infections in mosquitoes are controlled through an immune response called RNA interference (RNAi). It is however unknown whether immune responses changs when a mosquito is exposed to a co-infection of ZIKV with either DENV or CHIKV. In this study, we provide evidence that ZIKV co-infections with CHIKV or DENV are similarly well controlled by RNAi as single infections. These findings give new insights into the dynamics of arboviral co-infections in mosquito vectors that increase our understanding of co-infection scenarios during arbovirus outbreaks.</p>
Pivotal Study to Evaluate Safety and Immunogenicity of a Live-Attenuated Chikungunya Virus Vaccine Candidate in Adults
ClinicalTrials.gov study NCT04546724. IPD Sharing: NO. Countries: 1. Publications: 2.
Antibody Persistence And Long Term Safety Of A Chikungunya Virus Vaccine (VLA1553)
ClinicalTrials.gov study NCT04838444. IPD Sharing: YES. Countries: 1. Publications: 1.
Sylvatic Transmission of Zika, Dengue, and Chikungunya Viruses in Thailand and Cambodia
ClinicalTrials.gov study NCT04434846. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Chikungunya Virus Vaccine Trial in Healthy Adults
ClinicalTrials.gov study NCT01489358. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Phase 2 Open-label Study of Alum-adjuvanted Chikungunya Virus-like Particle Vaccine (PXVX0317)
ClinicalTrials.gov study NCT03992872. IPD Sharing: NO. Countries: 1. Publications: 1.
Data from: Development and proof of concept evaluation for a low-resource compatible Chikungunya virus diagnostic
Open the record for dataset details and reuse information.
RNA sequences for Aedes species, Dengue, and Chikungunya viruses
Open the record for dataset details and reuse information.
Fatal outcome of chikungunya virus infection in Brazil
Abstract Background Chikungunya virus (CHIKV) emerged in the Americas in 2013 and has caused ~2.1 million cases and over 600 deaths. A retrospective investigation was undertaken to describe clinical, epidemiological and virus genomic features associated with deaths caused by CHIKV in Ceará state, northeast Brazil. Methods Sera, cerebrospinal fluid (CSF) and tissue samples from 100 fatal cases with suspected arbovirus infection were tested for CHIKV, dengue (DENV) and Zika virus (ZIKV). Clinical, epidemiological and death reports were obtained for patients with confirmed CHIKV infection. Logistic regression analysis was undertaken to identify independent factors associated with risk of death during CHIKV infection. Phylogenetic analysis was conducted using whole genomes from a subset of cases. Results 68 fatal cases had CHIKV infection confirmed by RT-qPCR (52.9%), viral antigen (41.1%), and/or specific-IgM (63.2%). Co-detection of CHIKV with DENV were found in 22% of fatal cases, ZIKV in 2.9%, and DENV and ZIKV in 1.5%. A total of 39 CHIKV-deaths presented with neurological signs and symptoms, and CHIKV-RNA was found in the CSF of 92.3% of these patients. Fatal outcomes were associated with irreversible multiple organ dysfunction syndrome. Patients with diabetes appear to die at a higher frequency during the sub-acute phase. Genetic analysis showed circulation of two CHIKV-East Central South African (ECSA) lineages in Ceará and revealed no unique virus genomic mutation associated with fatal outcome. Conclusion The investigation of the largest cross-sectional cohort of CHIKV-deaths to date reveals that CHIKV-ECSA strains can cause death in individuals from both risk and non-risk groups, including young adults.
FIGURE 2 in The Asian tiger mosquito, Aedes (Stegomyia) albopictus (Skuse), a vector of dengue, chikungunya and zika viruses, reaches Portugal (Diptera: Culicidae)
FIGURE 2. Portuguese Aedes albopictus females seeking human blood. Note characteristic scutal white stripe, distinct silvery-white scales on the maxillary palpi and tarsi, as well as narrow scales over the wing root and silvery-white basolateral abdominal tergal markings.
FIGURE 1 in The Asian tiger mosquito, Aedes (Stegomyia) albopictus (Skuse), a vector of dengue, chikungunya and zika viruses, reaches Portugal (Diptera: Culicidae)
FIGURE 1. Distribution of Aedes albopictus in the Iberian Península. In green, distribution in Spain according to Collantes et al. (2016). In red, highlighted by arrow, new occurrence in Portugal.
FIGURE 3 in The Asian tiger mosquito, Aedes (Stegomyia) albopictus (Skuse), a vector of dengue, chikungunya and zika viruses, reaches Portugal (Diptera: Culicidae)
FIGURE 3. Biting activity of Ae. albopictus assessed by human-bait catches. Specimens arriving to bite were captured every 15 minutes to avoid recapture. The x axis is a timeline of 15-minute intervals; the y axis is an average of the three days of sampling.
Study to Assess the Safety and Immunogenicity of a Chikungunya Virus Vaccine Candidate (VLA1553) in Healthy Volunteers
ClinicalTrials.gov study NCT03382964. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Consequences of a Maternal-fetal Chikungunya Virus Infection
ClinicalTrials.gov study NCT04909411. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Against Chikungunya Virus and Neonatal Infection
ClinicalTrials.gov study NCT07190560. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
RT-PCR on Urine Samples: Added Value for the Diagnosis of Chikungunya Virus Infection
ClinicalTrials.gov study NCT02714985. IPD Sharing: NO. Countries: 2. Publications: 10.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.