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ShareScore release 0.9.0
Dataset results
13 results for “chronic malnutrition”
Malnutrition, Diet and Racial Disparities in Chronic Kidney Disease (CKD)
ClinicalTrials.gov study NCT01415570. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Malnutrition in Chronic Gastrointestinal Diseases, Cross-sectional Study
ClinicalTrials.gov study NCT04474743. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Chronic Malnutrition and Oral Health Status in Children Aged One to Five Years
ClinicalTrials.gov study NCT03529500. IPD Sharing: YES. Countries: 1. Publications: 19.
Community-based, Controlled, Open-label, Cluster-randomized Trial for the Reduction of Chronic Malnutrition in Children Under Two Years of Age, With Three Intervention Arms Grouped by Clusters, in Two
ClinicalTrials.gov study NCT05571280. IPD Sharing: NO. Countries: 1. Publications: 3.
Malnutrition in Chronic Pancreatitis, Trans-sectoral Study
ClinicalTrials.gov study NCT04476056. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Chronic Arsenic Exposure on Malnutrition of Under Five Children
ClinicalTrials.gov study NCT03893721. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
Data from: Experimental evolution demonstrates evolvability of preferential nutrient allocation to competing traits, in response to chronic malnutrition.
Investigating the evolutionary origins of disease vulnerability is an important aspect of evolutionary medicine that strongly complements our current understanding on proximate causes of disease. Life history trade-offs mediated through evolutionary changes in resource allocation strategies could be one possible explanation to why suboptimal traits that leave bodies vulnerable to disease exist. For example, Drosophila melanogaster populations experimentally evolved to tolerate chronic larval malnutrition succumb to intestinal infection despite eliciting a competent immune response, owing to the loss of their intestinal integrity. Here, I test if evolved changes in resource allocation underlies this trade-off, by assaying preferential allocation of dietary protein towards growth and tissue repair in the same populations. Using two phenotypic traits: regeneration of intestinal epithelium post-pathogenic infection and body weight, I show that in accordance to the dynamic energy budget theory (DEB) dietary protein acquired during the larval phase is allocated to both growth and adult tissue repair. Furthermore, by altering the ratio of protein and carbohydrates in the larval diets I demonstrate that in comparison to the control populations, the evolved (selected) populations differ in their protein allocation strategy towards these two traits. While the control populations stored away excess protein for tissue repair, the selected populations invested it towards immediate increase in body weight rather than towards an unanticipated tissue damage. Thus, I show how macronutrient availability and their allocation between traits can alter resistance, and provide empirical evidence that supports the 'mismatch hypothesis', wherein vulnerability to disease is proposed to stem from the differences between ancestral and current environment.
Data from: Experimental evolution demonstrates evolvability of preferential nutrient allocation to competing traits, in response to chronic malnutrition.
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Data from: Chronic malnutrition favours smaller critical size for metamorphosis initiation in Drosophila melanogaster
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Maternal Nutritional Status Modifies Heat-Associated Growth Restriction in Women with Chronic Malnutrition
GEO Series GSE220877. Homo sapiens. 126 samples. Type: Expression profiling by high throughput sequencing.
Optimizing Treatment Programs for Chronic Kidney Disease-mineral and Bone Disorder and Malnutrition
ClinicalTrials.gov study NCT02005302. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Nutritional Intervention With Tenebrio Molitor Powder in Children With Chronic Malnutrition in the Democratic Republic of the Congo
ClinicalTrials.gov study NCT07284095. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Dangerous Triad in Ageing and in Chronic Obstructive Pulmonary Disease (COPD) - Reduced Muscle Mass, Impaired Muscle Function and Malnutrition
ClinicalTrials.gov study NCT01179178. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.