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264 results for “compromise”
Dataset of 'HIV infection is associated with compromised tumor microenvironment adaptive immune reactivity in Hodgkin Lymphoma'
<p><span><span>§<span> </span></span></span><strong><span>:</span></strong><span>The data were generated using the i) GeoMx Digital Spatial Profiler (DSP) platform developed by Nanostring Technologies. GeoMx analysis utilizes <em>in situ </em>RNA hybridization with Whole Atlas Transcriptome probe (Nanostring) and ii) HTG platform (Immune Response kit) Our dataset comprises samples from donors categorized as HLposHIVnegEBVneg, HLposHIVposEBVpos, or HLposHIVnegEBVpos (HL: Hodgkin Lymphoma). Regions of interest (ROI) were spatially profiled to capture distinct molecular signatures associated with these donor categories.</span></p>
Malware Finances and Operations: a Data-Driven Study of the Value Chain for Infections and Compromised Access
<p><strong>Description</strong><br> <br> The datasets demonstrate the malware economy and the value chain published in our paper, <a href="https://doi.org/10.1145/3600160.3605047"><em>Malware Finances and Operations: a Data-Driven Study of the Value Chain for Infections and Compromised Access</em></a>, at the 12th International Workshop on Cyber Crime (IWCC 2023), part of the ARES Conference, published by the International Conference Proceedings Series of the ACM ICPS.</p> <p>Using the well-documented scripts, it is straightforward to reproduce our findings. It takes an estimated 1 hour of human time and 3 hours of computing time to duplicate our key findings from MalwareInfectionSet; around one hour with VictimAccessSet; and minutes to replicate the price calculations using AccountAccessSet. See the included README.md files and Python scripts.</p> <p>We choose to represent each victim by a single JavaScript Object Notation (JSON) data file. Data sources provide sets of victim JSON data files from which we've extracted the essential information and omitted Personally Identifiable Information (PII). We collected, curated, and modelled three datasets, which we publish under the <a href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>.</p> <p><strong>1. MalwareInfectionSet</strong><br> We discover (and, to the best of our knowledge, document scientifically for the first time) that malware networks appear to dump their data collections online. We collected these infostealer malware logs available for free. We utilise 245 malware log dumps from 2019 and 2020 originating from 14 malware networks. The dataset contains 1.8 million victim files, with a dataset size of 15 GB.</p> <p><strong>2. VictimAccessSet</strong><br> We demonstrate how Infostealer malware networks sell access to infected victims. Genesis Market focuses on user-friendliness and continuous supply of compromised data. Marketplace listings include everything necessary to gain access to the victim's online accounts, including passwords and usernames, but also detailed collection of information which provides a clone of the victim's browser session. Indeed, Genesis Market simplifies the import of compromised victim authentication data into a web browser session. We measure the prices on Genesis Market and how compromised device prices are determined. We crawled the website between April 2019 and May 2022, collecting the web pages offering the resources for sale. The dataset contains 0.5 million victim files, with a dataset size of 3.5 GB.</p> <p><strong>3. AccountAccessSet</strong><br> The Database marketplace operates inside the anonymous Tor network. Vendors offer their goods for sale, and customers can purchase them with Bitcoins. The marketplace sells online accounts, such as PayPal and Spotify, as well as private datasets, such as driver's licence photographs and tax forms. We then collect data from Database Market, where vendors sell online credentials, and investigate similarly. To build our dataset, we crawled the website between November 2021 and June 2022, collecting the web pages offering the credentials for sale. The dataset contains 33,896 victim files, with a dataset size of 400 MB.</p> <p><strong>Credits Authors</strong></p> <ul> <li>Billy Bob Brumley (Tampere University, Tampere, Finland)</li> <li>Juha Nurmi (Tampere University, Tampere, Finland)</li> <li>Mikko Niemelä (Cyber Intelligence House, Singapore)</li> </ul> <p><strong>Funding</strong></p> <p>This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme under project numbers 804476 (SCARE) and 952622 (SPIRS).<br> <br> <strong>Alternative links to download:</strong> <a href="https://mega.nz/folder/aJwVyIYJ#9SWh-Z3-TpPfjHZeFxbeew">AccountAccessSet</a>, <a href="https://mega.nz/folder/iUQ3RaKB#48ZkXnFYSR0qXLcbkrZLqw">MalwareInfectionSet</a>, and <a href="https://mega.nz/folder/aNYCFCrK#pbDkJL-PNWjn1ABXbtdR4w">VictimAccessSet</a>.</p>
Fig. 7 in Fig. 7 in Coexistence of Juvenile with Adult at Culebra Beach, Panama: A Temporal-spatial Partitioning Compromise.
Fig. 7. Non-metric Multidimensional Scaling plot of the activity budget of the juvenile and adult Ocypode gaudichaudii from Culebra Beach superimposed with Bray-Curtis cluster analysis using 60% and 80% similarity. 2D stress = 0.15.
Fig. 3 in Fig. 7 in Coexistence of Juvenile with Adult at Culebra Beach, Panama: A Temporal-spatial Partitioning Compromise.
Fig. 3. Boxplots of the median carapace width and interquartile range of Ocypode gaudichaudii during the day and night at Culebra Beach. Dark bands represent medians, boxes represent interquartile range and whiskers represent 1.5 times the interquartile range.
Fig. 6 in Fig. 7 in Coexistence of Juvenile with Adult at Culebra Beach, Panama: A Temporal-spatial Partitioning Compromise.
Fig. 6. Mean proportion of time (± S.E.) that Ocypode gaudichaudii from Culebra Beach were engaged in seven behaviors after burrow emergence. ScF, scavenging; DepF, deposit-feeding; Probe, probing for food; BurM, burrow maintenance; Walk, walking; In bur, staying within the burrow; Rest, resting at the burrow entrance.
Fig. 2 in Fig. 7 in Coexistence of Juvenile with Adult at Culebra Beach, Panama: A Temporal-spatial Partitioning Compromise.
Fig. 2. Location of Culebra Beach with the inset showing a 30 × 30 m plot marked out as the sampling area across six five-metre zones (zone 1 to zone 6). The area was divided into 36 (5 × 5 m) quadrats.
Fig. 5 in Fig. 7 in Coexistence of Juvenile with Adult at Culebra Beach, Panama: A Temporal-spatial Partitioning Compromise.
Fig. 5. Burrow densities of the juvenile and adult Ocypode gaudichaudii in zones 1 to 3 of Culebra Beach during the night with respect to the high and low tide levels from 9 June to 29 November, 2012.
Fig. 4 in Fig. 7 in Coexistence of Juvenile with Adult at Culebra Beach, Panama: A Temporal-spatial Partitioning Compromise.
Fig. 4. Burrow densities of the juvenile and adult Ocypode gaudichaudii at zones 1 to 5 of Culebra Beach during the day with respect to the high and low tide levels from 9 June to 29 November, 2012.
On the conversion of CO2 to value added products over composite PdZn and H-ZSM-5 catalysts: excess Zn over Pd, a compromise or a penalty? Supplementary information
<p>Supplementary Material: N2 adsorption, TEM, XAS, PXRD, test results</p>
Escalated begging does not compromise nestling health
Open the record for dataset details and reuse information.
Data from: Compromise docking power evaluation of liganded crystal structures of Mpro SARS-CoV-2
<p>A set of 406 liganded SARS-CoV-2 M<sup>pro</sup> crystal structures originally downloaded from RCSB PBD database is provided. Ligand and protein files are processed and corrected for various types of structural errors and are provided in pdbqt and mol2 formats for immediate use in molecular docking programs AutoDock, AutoDock Vina, and PLANTS. Data are utilized in calculations of newly defined compromise docking power to monitor the performance of above-mentioned software. The provided dataset can also be used for benchmarking of other software and molecular docking protocols on liganded SARS-CoV-2 M<sup>pro</sup> systems.</p>
Increasing adult density compromises survival following bacterial infections in Drosophila melanogaster
<p>The density-dependent prophylaxis hypothesis predicts that risk of pathogen transmission increases with increase in population density, and in response to this, organisms mount a prophylactic immune response when exposed to high density. This prophylactic response is expected to help organisms improve their chances of survival when exposed to pathogens. Alternatively, organisms living at high densities can exhibit compromised defense against pathogens due to lack of resources and density associated physiological stress; the crowding stress hypothesis. We housed adult Drosophila melanogaster flies at different densities and measured the effect this has on their post-infection survival and resistance to starvation. We find that flies housed at higher densities show greater mortality after being infected with bacterial pathogens, while also exhibiting increased resistance to starvation. Our results are more in line with the density-stress hypothesis that postulates a compromised immune system when hosts are subjected to high densities.</p>
Fig. 1 in Fig. 7 in Coexistence of Juvenile with Adult at Culebra Beach, Panama: A Temporal-spatial Partitioning Compromise.
Fig. 1. Beach profile showing the burrow zones of Ocypode gaudichaudii at Culebra Beach.
Input data from the paper: Small room for compromise between oil palm cultivation and primate conservation in Africa
<p>All the raw input data needed to replicate the analyses from the paper:</p> <p><strong>Strona G., S. D. Stringer, G. Vieilledent, Z. Szantoi, J. Garcia-Ulloa, S. Wich.</strong> Small room for compromise between oil palm cultivation and primate conservation in Africa.</p>
Output from: Small room for compromise between oil palm cultivation and primate conservation in Africa
<p>Expected results from the scripts associated to the paper<strong>:</strong></p> <p><strong>Strona G., S. D. Stringer, G. Vieilledent, Z. Szantoi, J. Garcia-Ulloa, S. Wich.</strong> Small room for compromise between oil palm cultivation and primate conservation in Africa.</p>
More intraguild prey than pest species in arachnid diets may compromise biological control in apple orchards
<p>Understanding the full diet of natural enemies is necessary for evaluating their role as biocontrol agents, because many enemy species do not only feed on pests but also on other natural enemies. Such intraguild predation can compromise pest control if the consumed enemies are actually better for pest control than their predators. In this study, we used gut metabarcoding to quantify diets of all common arachnid species in Swedish and Spanish apple orchards. For this purpose, we designed new primers that reduce amplification of arachnid predators while retaining high amplification of all prey group. Results suggest that most arachnids consume a large range of putative pest species on apple but also a high proportion of other natural enemies, where the latter constitute almost a third of all prey sequences. Intraguild predation also varied between regions, with a larger content of heteropteran bugs in arachnid guts from Spanish orchards. There was also a tendency for cursorial spiders to have more intraguild prey in the gut than web spiders. Two groups that may be overlooked as important biocontrol agents in apple orchards seem to be theridiid web spiders and opilionids, where the latter had several small-bodied pest species in the gut. These results thus provide important guidance for what arachnid groups that should be targets of management actions, even though additional information is needed to quantify all direct and indirect interactions occurring in the complex arthropod food webs in fruit orchards.</p>
A non‐native C‐terminal extension of the β' subunit compromises RNA polymerase and Rho functions
<p><em>Escherichia</em> <em>coli</em> RfaH abrogates Rho‐mediated polarity in lipopolysaccharide core biosynthesis operons, and ΔrfaH cells are hypersensitive to antibiotics, bile salts, and detergents. Selection for rfaH suppressors that restore growth on SDS identified a temperature‐sensitive mutant in which 46 C‐terminal residues of the RNA polymerase (RNAP) β' subunit are replaced with 23 residues carrying a net positive charge. Based on similarity to rpoC397, which confers a temperature‐sensitive phenotype and resistance to bacteriophages, we named this mutant rpoC397*. We show that SDS resistance depends on a single nonpolar residue within the C397* tail, whereas basic residues are dispensable. In line with its mimicry of RfaH, C397* RNAP is resistant to Rho but responds to pause signals, NusA, and NusG in vitro similarly to the wild‐type enzyme and binds to Rho and Nus factors in vivo. Strikingly, the deletion of rpoZ, which encodes the ω "chaperone" subunit, restores rpoC397* growth at 42°C but has no effect on SDS sensitivity. Our results suggest that the C397* tail traps the ω subunit in an inhibitory state through direct contacts and hinders Rho‐dependent termination through long‐range interactions. We propose that the dynamic and hypervariable β'•ω module controls RNA synthesis in response to niche‐specific signals.</p>
Can we Reduce Hospital Attendance Without Compromising Care by the Use of Telephone Consultation
ClinicalTrials.gov study NCT00129701. IPD Sharing: NO. Countries: 1. Publications: 6.
A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System
ClinicalTrials.gov study NCT05438602. IPD Sharing: YES. Countries: 9. Publications: 3.
Study to Monitor the Occurrence of Viral Variants in Patients With Compromised Immune Systems Being Treated for COVID-19
ClinicalTrials.gov study NCT05305651. IPD Sharing: YES. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.