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52 results for “cortical bone”
Large cortical bone pores in the tibia are associated with proximal femur strength - data for reproduction
<p>Results tables for the reproduction of:</p> <p>Iori G, Schneider J, Reisinger A, Heyer F, Peralta L, Wyers C, et al. Large cortical bone pores in the tibia are associated with proximal femur strength. PLOS ONE. doi:10.1371/journal.pone.0215405</p>
Geometry models of specimens: Micro-CT, Mechanical, and Histological Examination of the Effect of Local Adjuvants on Porcine Cortical Bone Following Intralesional Curettage of Bone Tumors.
<p>Bone samples for micro CT measurements and reconstructed bone geometry from micro CT data.</p>
3D Cortical Bone and Trabecular Bone Structure [synthetic data, simple, capsule shell model]
<p>Trabecular bone patterns are mimicked by generating and arranging "capsule shells" in a three-dimensional voxel by following probability distribution. Ground truth (gt) contains 4 labels (Background: 0, Cortical Bone: 11, Trabecular Bone: 21, Cavity: 31).</p>
Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft
ClinicalTrials.gov study NCT01588444. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Dataset: Segmentation of cortical bone, trabecular bone, and medullary pores from micro-CT images using 2D and 3D deep learning models
Open the record for dataset details and reuse information.
A novel methodological approach to simultaneously extract high quality total RNA and proteins from cortical and trabecular bone
<p>Molecular differences between cortical and trabecular bone, of relevance to understand the pathophysiological bases of bone diseases, can be determined only throughout effective isolation methods for RNA and proteins. Here we present a TRIzol-based method, combining bone pulverization and homogenization, to extract simultaneously total RNA and proteins from human cortical and trabecular bone from the same carrot. RNA integrity and purity were determined as the 260-to-280 nm and 260-to-230 nm absorbance- ratios, and 28S-to-18S rRNA ratio. Protein integrity and quality were evaluated by Comassie Blue staining. RT-qPCR and immunoblotting for bone-specific genes and proteins were performed to verify the suitability of the isolated material in downstream applications. 260-to-280 nm and 260-to-230 nm absorbance ratios were, on average, ≥1.8. Bands on agarose gel were consistent to an intact RNA, with mean 28S-to-18S ratios of1.68±0.35 and 1.88±0.10 for cortical and trabecular bone, respectively. Band patterns after Comassie Blue staining confirmed protein integrity. Successful gene and protein expression analysis, with relevant differences between the two compartments, highlighted the suitability of the material in downstream applications. The method here presented is appropriate and effective for the study of human bone.</p>
Spatial metabolomics reveal upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice
<p>Imaging mass spectrometry data (.imzML format) from bones of <em>Hyp </em>(hypophosphatemia) mice and wild-type controls. Detailed information is given in the publication by Buck & Prade et al. "Spatial metabolomics reveal upregulation of several pyrophosphate-producing pathways in cortical bone of <em>Hyp</em> mice" in JCI Insight.</p>
Cortical Bone Assessment Using Ultrasonic Guided Waves: Towards a Robust Clinical Measurement
ClinicalTrials.gov study NCT05424536. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Cortical Bone Trajectory Screws vs. Traditional Pedicle Screws Fixation
ClinicalTrials.gov study NCT03105167. IPD Sharing: YES. Countries: 1. Publications: 21.
Medial Displacement Calcaneal Osteotomy and FDL- Transfer - With a Human, Allogeneic Cortical Bone Screw
ClinicalTrials.gov study NCT05643079. IPD Sharing: NO. Countries: 1. Publications: 9.
Age Influence on Cortical Bone Measured by Ultrasound
ClinicalTrials.gov study NCT03453242. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
METHODS. Bovine ilia were used in the simulations because their histological structure (a fibrolamellar cortex overlying cancellous bone26) was found to match that of the Triceratops ilium. Bone sections 10 x 50 x 縠 3.0 cm with cortices ranging from 0.5 to 5.5 mm in depth (the range of initial cortical-thickness estimates based on gross morphology) were mounted on a servohydraulic mechanical loading frame (MTS Bionix, Minneapolis) and penetrated with an aluminium-bronze T. rex tooth replica. The replica was cast from an actual adult T. rex maxillary tooth, after casts made from some ofthe deeper bite marks revealed the size and shape of the teeth that had impacted the pelvis8 • The replica was penetrated into the ilia sections at 1 mm s-1 to a depth of 11.5 mm, equivalent to the maximum depth of the deepest ilium bite mark8 • Forces were measured with an MTS 25 N strain-gauge-based axial load cell accurate to 0.2%. The forces increased with increasing penetration depth even after the cortical layer had been perforated and the underlying cancellous bone was being crushed. The increase in force with penetration depth is attributed to a greater cortical surface area coming into contact with the semi-conical penetrator tooth as it descended through the ilia. in Bite-force estimation for Tyrannosaurus rex from tooth-marked bones
METHODS. Bovine ilia were used in the simulations because their histological structure (a fibrolamellar cortex overlying cancellous bone26) was found to match that of the Triceratops ilium. Bone sections 10 x 50 x 縠 3.0 cm with cortices ranging from 0.5 to 5.5 mm in depth (the range of initial cortical-thickness estimates based on gross morphology) were mounted on a servohydraulic mechanical loading frame (MTS Bionix, Minneapolis) and penetrated with an aluminium-bronze T. rex tooth replica. The replica was cast from an actual adult T. rex maxillary tooth, after casts made from some ofthe deeper bite marks revealed the size and shape of the teeth that had impacted the pelvis8 • The replica was penetrated into the ilia sections at 1 mm s-1 to a depth of 11.5 mm, equivalent to the maximum depth of the deepest ilium bite mark8 • Forces were measured with an MTS 25 N strain-gauge-based axial load cell accurate to 0.2%. The forces increased with increasing penetration depth even after the cortical layer had been perforated and the underlying cancellous bone was being crushed. The increase in force with penetration depth is attributed to a greater cortical surface area coming into contact with the semi-conical penetrator tooth as it descended through the ilia.
Data from: Nanoindentation analysis of the micromechanical anisotropy in mouse cortical bone
Studies investigating micromechanical properties in mouse cortical bone often solely focus on the mechanical behaviour along the long axis of the bone. Therefore, data on the anisotropy of mouse cortical bone is scarce. The aim of this study is the first-time evaluation of the anisotropy ratio between the longitudinal and transverse directions of reduced modulus and hardness in mouse femurs by using the nanoindentation technique. For this purpose, nine 22-week-old mice (C57BL/6) were sacrificed and all femurs extracted. A total of 648 indentations were performed with a Berkovich tip in the proximal (P), central (C) and distal (D) regions of the femoral shaft in the longitudinal and transverse directions. Higher values for reduced modulus are obtained for indentations in the longitudinal direction, with anisotropy ratios of 1.72 ± 0.40 (P), 1.75 ± 0.69 (C) and 1.34 ± 0.30 (D). Hardness is also higher in the longitudinal direction, with anisotropic ratios of 1.35 ± 0.27 (P), 1.35 ± 0.47 (C) and 1.17 ± 0.19 (D). We observed a significant anisotropy in the micromechanical properties of the mouse femur, but the correlation for reduced modulus and hardness between the two directions is low (r2 < 0.3) and not significant. Therefore, we highly recommend performing independent indentation testing in both the longitudinal and transverse directions when knowledge of the tissue mechanical behaviour along multiple directions is required.
Bone mineral density & hand x-ray cortical percentages in females
<p>This data set serves as a resource for correlating hand x-rays with bone mineral density (BMD) scans taken within one year of one another. The need for increased methods of screening for low BMD is needed. Therefore, we used this dataset to determine if hand and wrist x-rays could be used to screen for forearm osteopenia and osteoporosis. </p>
Data file for Augoyard et al.'s article, "Evaluation of age, sex, and ancestry-related variation in cortical bone and dentine volumes in modern humans, and a preliminary assessment of cortical bone-dentine covariation in later Homo"
<p>The following dataset is related to Augoyard et al.'s article: <em>Evaluation of age, sex, and ancestry-related variation in cortical bone and dentine volumes in modern humans, and a preliminary assessment of cortical bone-dentine covariation in later Homo</em>, submitted in september 2022 to the <em>Journal of Archaeological Sciences</em>.</p>
Bone mineral density & hand x-ray cortical percentages in females
Open the record for dataset details and reuse information.
Data from: Nanoindentation analysis of the micromechanical anisotropy in mouse cortical bone
Open the record for dataset details and reuse information.
Single Cell Cortical Bone Transcriptomics from Sost-Cre
GEO Series GSE208152. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic profiling of cortical bone from hindlimb unloaded mice
GEO Series GSE169292. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Role of PTH on Gene Expression in Osteocytes of Cortical Long Bone from Mature Mice
GEO Series GSE61146. Mus musculus. 6 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.