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ShareScore release 0.9.0
Dataset results
10 results for “cyanocobalamin”
Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for Vertigo
ClinicalTrials.gov study NCT05221892. IPD Sharing: NO. Countries: 1. Publications: 10.
Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status
ClinicalTrials.gov study NCT02679833. IPD Sharing: NO. Countries: 1. Publications: 2.
Oral Cyanocobalamin (Eligen B12) Bioavailability Study
ClinicalTrials.gov study NCT01311739. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Effect of Polyvitaminics (Pyridoxine Hydrochloride, Folic Acid and Cyanocobalamin) in the Concentration of Homocysteine and Lipid Profile in Postmenopausal Women: a Randomized Controlled, Double-blind
ClinicalTrials.gov study NCT03221816. IPD Sharing: Not stated. Countries: 0. Publications: 12.
Comparison of Cyanocobalamin in Avocado Oil Cream With Steroid Combination Ointment
ClinicalTrials.gov study NCT05330936. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Methylcobalamin and Cyanocobalamin Consumption on Vitamin B12 Nutritional Status
ClinicalTrials.gov study NCT05785585. IPD Sharing: NO. Countries: 1. Publications: 0.
Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis
ClinicalTrials.gov study NCT04197115. IPD Sharing: NO. Countries: 1. Publications: 0.
Characterization of Cyanocobalamin in Healthy Voluteers After Intranasal and Intramuscual Administration
ClinicalTrials.gov study NCT01306123. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Cyanocobalamin as Photosensitizing Agent
ClinicalTrials.gov study NCT05395650. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Homocysteine, folic acid, cyanocobalamin, and frailty in older people: findings from the "Invece. Ab" Study
<p><strong>The database includes</strong> the raw data of the article “Homocysteine, Folic Acid, Cyanocobalamin, and Frailty in Older People: Findings From the “Invece. Ab” Study”.</p> <p><strong>Aim of the work</strong> was to verify the association of homocysteine (HOcy), cyanocobalamin (B12), and folic acid (FO) plasma concentrations with frailty and to underline the influence of these biomarkers on frailty incidence in a community dwelling older population, studied longitudinally (2012, 2014 and 2018 waves).</p> <p><strong>The database contains</strong> data obtained by the evaluations of plasma levels of i) HOcy, ii) B12 and iii) FO using chemiluminescent microparticle immunoassay on an Architect 2000 analyzer (Abbott) within 3h of blood collection. Briefly, we found that frail subjects increased from the 2014 wave to the 2018 wave of the study. Moreover, the median concentration of HOcy increased with age only in males and it showed a significant positive correlation with the Frailty Index (FI) at all three waves of the study; no positive correlation was instead reported for B12 and FO. HOcy seems to be a predictor of cumulative incidence of frailty (during the six years of the study), independent of age, sex, and education, although HOcy80 (19.4μmol/l - cutoff for the 80th percentile) showed only a positive trend in this sense. On the contrary HOcy90 (23.3μmol/l - cutoff for the 90th percentile) significantly influenced the cumulative incidence of frailty. B12 and FO showed no relationship with the cumulative incidence of frailty. Finally, subjects with plasma HOcy concentrations in the top quintile (HOcy80) had five fewer frailty-free months; this finding was independent of age, sex, and education. A comparable frailty-free survival time, was found for plasma HOcy concentrations in the top decile (HOcy90).</p> <p><strong>To conclude</strong>, high plasma concentrations of HOcy, could be a factor that increases the likelihood of becoming frail and becoming frail sooner; these results showed a clear association with frailty. Moreover, the role of B12 and FO plasma concentrations was found to be marginal.</p>
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