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8 results for “data donation”

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zenodo36/100

Raw Data for the article: How important is the role of iterative liver direct surgery in patients with hepatocellular carcinoma for a transplant center located in an area with a low rate of deceased donation?

<p><strong>Introduction:&nbsp;</strong>Hepatocellular carcinoma (HCC) accounts for nearly 90% of primary liver cancers, with estimates of over 1 million people affected by 2025. We aimed to explore the impacting role of an iterative surgical treatment approach in a cohort of HCC patients within the Milan criteria, associated with clinical risk factors for tumor recurrence (RHCC) after liver transplant (LT) and loco-regional therapies (LRT), as well as liver resection (LR) and/or microwave thermal ablation (MWTA).</p> <p><strong>Methods:&nbsp;</strong>We retrospectively analyzed our experience performed during an 8-year period between January 2013 and December 2021 in patients treated for HCC, focusing on describing the impact on preoperative end-stage liver disease severity, oncologic staging, tumor characteristics, and surgical treatments. The Cox model was used to evaluate variables that could predict relapse risks. Relapse risk curves were calculated according to the Kaplan-Meier method, and the log-rank test was used to compare them.</p> <p><strong>Results:&nbsp;</strong>There were 557 HCC patients treated with a first-line approach of LR and/or LRTs (<em>n</em>&nbsp;= 335) or LT (<em>n</em>&nbsp;= 222). The median age at initial transplantation was 59 versus 68 for those whose first surgical approach was LR and/or LRT. In univariate analysis with the Cox model, nodule size was the single predictor of recurrence of HCC in the posttreatment setting (HR: 1.61, 95% CI: 1.05-2.47,&nbsp;<em>p</em>&nbsp;= 0.030). For the LRT group, we have enlightened the following clinical characteristics as significantly associated with RHCC: hepatitis B virus infection (which has a protective role with HR: 0.34, 95% CI: 0.13-0.94,&nbsp;<em>p</em>&nbsp;= 0.038), number of HCC nodules (HR: 1.54, 95% CI: 1.22-1.94,&nbsp;<em>p</em>&nbsp;&lt; 0.001), size of the largest nodule (HR: 1.06, 95% CI: 1.01-1.12,&nbsp;<em>p</em>&nbsp;= 0.023), serum bilirubin (HR: 1.57, 95% CI: 1.03-2.40,&nbsp;<em>p</em>&nbsp;= 0.038), and international normalized ratio (HR: 16.40, 95% CI: 2.30-118.0,&nbsp;<em>p</em>&nbsp;= 0.006). Among the overall 111 patients with RHCC in the LRT group, 33 were iteratively treated with further curative treatment (12 were treated with LR, two with MWTA, three with a combined LR-MWTA treatment, and 16 underwent LT). Only one of 18 recurrent patients previously treated with LT underwent LR. For these RHCC patients, multivariable analysis showed the protective roles of LT for primary RHCC after IDLS (HR: 0.06, 95% CI: 0.01-0.36,&nbsp;<em>p</em>&nbsp;= 0.002), of the time relapsed between the first and second IDLS treatments (HR: 0.97, 95% CI: 0.94-0.99,&nbsp;<em>p</em>&nbsp;= 0.044), and the impact of previous minimally invasive treatment (HR: 0.28, 95% CI: 0.08-1.00,&nbsp;<em>p</em>&nbsp;= 0.051).</p> <p><strong>Conclusion:&nbsp;</strong>The coexistence of RHCC with underlying cirrhosis increases the complexity of assessing the net health benefit of ILDS before LT. Minimally invasive surgical therapies and time to HCC relapse should be considered an outcome in randomized clinical trials because they have a relevant impact on tumor-free survival.</p>

opencc-by-4.0Feb 2023View details →
dryad32/100

Data from: Food sharing in vampire bats: reciprocal help predicts donations more than relatedness or harassment

Open the record for dataset details and reuse information.

publicFeb 2013View details →
dryad24/100

Data from: Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation

Background The transplant community increasingly accepts extended criteria live kidney donors, however, great (geographical) differences are present in policies regarding the acceptance of these donors, and guidelines do not offer clarity. The aim of this survey was to reveal these differences and to get an insight in both centre policies as well as personal beliefs of transplant professionals. Methods An online survey was sent to 1128 ESOT-members. Questions were included about several extended donor criteria; overweight/obesity, older age, vascular multiplicity, minors as donors and comorbidities; hypertension, impaired fasting glucose, kidney stones, malignancies and renal cysts. Comparisons were made between transplant centres of three regions in Europe and between Europe and other countries worldwide. Results 331 questionnaires were completed by professionals from 55 countries. Significant differences exist between regions in Europe in acceptance of donors with several extended criteria. Median refusal rate for potential live donors is 15%. Furthermore, differences are seen regarding pre-operative work-up, both in specialists who perform screening as in preoperative imaging. Conclusions Remarkably, 23.4% of transplant professionals sometimes deviate from their centre policy, resulting in more or less comparable personal beliefs regarding extended criteria. Variety is seen, proving the need for a standardized approach in selection, preferably evidence based.

opencc-zeroDec 2016View details →
dryad24/100

Data from: Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation

Open the record for dataset details and reuse information.

publicJul 2018View details →
ClinicalTrials.gov20/100

Data Donation Model for Inclusive Cardiovascular Prevention Using the TRAIN Health Platform

ClinicalTrials.gov study NCT07238036. IPD Sharing: Not stated. Countries: 0. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
zenodo16/100

Data Donation with Dona: De-identified Messaging Data (WhatsApp and Facebook) and Evaluation Responses

<p><strong>General information</strong></p> <p>The dataset contains de-identified messaging meta-data from 78 WhatsApp and 7 Facebook data donations. The dataset was collected in an online study using the data donation platform Dona. After donating their messaging data, the study participants viewed visual summaries of their messaging data and evaluated this visual feedback. The responses to the evaluation questions and the sociodemographic data of the participants are also included in the dataset. &nbsp;</p> <p>The data was collected from August 2022 to June 2024.&nbsp;</p> <p>For more information on Dona, the associated publications and updates, please visit https://mbp-lab.github.io/dona-blog/.&nbsp;</p> <p><strong>File description<br></strong></p> <ol> <li><code>donation_table.csv </code>- contains general information about the donations including <ul> <li><em>donation_id</em>: donation identifier</li> <li><em>donor_id</em>: the ID of the donor to distinguish the messages sent by them from those sent by contacts</li> <li><em>source</em>: the messaging platform from which the data is donated (WhatsApp or Facebook)</li> <li><em>external_id</em>: ID used to connect messaging data with the survey data</li> </ul> </li> <li>&nbsp;<code>messages_table.csv</code> - contains the donated messages including<br> <ul> <li><em>conversation_id</em>: chat identifier</li> <li><em>sender_id</em>: sender identifier</li> <li><em>datetime</em>: time of the message, UNIX time for Facebook and device time for WhatsApp</li> <li><em>word_count</em>: word count of the messages achieved by splitting the text based on whitespace</li> <li><em>donation_id</em>: donation identifier (also listed in <code>donation_table.csv</code>)</li> </ul> </li> <li><code>messages_filtered_table.csv </code>- same structure as <code>messages_table.csv</code> except that chats with no considerable interactions were removed. This was defined as chats where donor's word count contribution was less than 10% or more than 90%.&nbsp;</li> <li><code>survey.xlsx </code>&rarr; contains survey responses of the participants.</li> <li><code>survey_table_coding.xlsx </code>&rarr; contains the mapping between the column names in <code>survey.xlsx </code>and their meaning, including the original survey questions and response options. Different sheets of the Excel file detail the survey questions and responses in one of the study languages (English, German, Armenian).&nbsp;</li> </ol> <p>&nbsp;</p>

restrictedDec 2023View details →
geo12/100

Expression data from an ex vivo ischaemia reperfusion model of renal deceased by cardiac death (DCD) donation in rat

GEO Series GSE36671. Rattus norvegicus. 4 samples. Type: Expression profiling by array.

openGEO-OpenMar 2012View details →
geo12/100

Expression data from a model of renal deceased by cardiac death (DCD) donation in rat

GEO Series GSE35555. Rattus norvegicus. 3 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2012View details →

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DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

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electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

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Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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