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199 results for “demyelinating”
Multi-omic approach to identify phenotypic modifiers underlying cerebral demyelination in X-linked adrenoleukodystrophy
<p>These are the data tables used to produce results in the publication:</p> <p>"Multi-omic approach to identify phenotypic modifiers underlying cerebral demyelination in X-linked adrenoleukodystrophy."<br> Phillip A. Richmond & Frans van der Kloet et al.</p> <p>Submitting to Frontiers in Cellular and Developmental Biology, 2020, Peroxisomal Special Issue. </p> <p>These tables include normalized measurements from four omics technologies, with no identifying information included. For details on processing, see the manuscript or contact:</p> <p>prichmond (at) cmmt (dot) ubc (dot) ca. </p> <p>Description of Files</p> <ul> <li>Sample mapping <ul> <li>20180314_sib_pairs.xlsx <ul> <li>Excel sheet describing family numbering, etc. used as a mapping table within the sheets below. </li> </ul> </li> </ul> </li> <li>Methylation: <ul> <li>DMRs_5_Families_ALL_0.10DB_Dec2019.csv <ul> <li>Significant methylated regions with delta beta at least 10 percent when a single family is left out</li> </ul> </li> <li>ALD_Deconvoluted_Betas_Dec2019.csv <ul> <li>All fitted betas for every subject (single CpG)</li> </ul> </li> <li>ALD_Limma_Final_Dec2019_CHR.csv <ul> <li>All fitted effects using limma modeling per CpG </li> </ul> </li> </ul> </li> <li>RNA: <ul> <li>Count_data.txt <ul> <li>The raw count table summed at the gene level using featureCounts.</li> </ul> </li> <li>Pvalues_all_23_01_2019.csv <ul> <li>All pvalues and log fold changes for the genes included in the modeling process (also with family left out)</li> </ul> </li> <li>Tmm_norm_counts_5_2_2020.csv <ul> <li>Tmm normalized RNA count data</li> </ul> </li> </ul> </li> <li>Proteomic <ul> <li>Report_Precursor_Peptides.xls <ul> <li>The proteomic data as an excel spreadsheet</li> </ul> </li> </ul> </li> <li>Pvalues_prot_13_3_2019.xlsx <ul> <li>The pvalues and log fold changes (also with family left out)</li> </ul> </li> <li>Lipids: <ul> <li>Lipid_data.csv <ul> <li>The lipid data (metabolites with missings are removed)</li> </ul> </li> <li>Pvalues_lipids.csv <ul> <li>Pvalues for the lipid data (also with family left out)</li> </ul> </li> </ul> </li> </ul> <p><br> NOTE: For use of these data files for processing and reproducing results of the manuscript, please see https://github.com/Phillip-a-richmond/ALD_Modifier_Project. </p> <p> </p>
Evaluate Efficacy and Safety of Fingolimod 0.5 mg Orally Once Daily Versus Placebo in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients.
ClinicalTrials.gov study NCT01625182. IPD Sharing: UNDECIDED. Countries: 15. Publications: 1.
Hematopoietic Stem Cell Transplantation in Chronic Inflammatory Demyelinating Polyneuropathy
ClinicalTrials.gov study NCT00278629. IPD Sharing: NO. Countries: 1. Publications: 1.
Immune Globulin Intravenous (IGIV) For Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
ClinicalTrials.gov study NCT00220740. IPD Sharing: Not stated. Countries: 10. Publications: 7.
Study of Efficacy and Safety of Privigen in Subjects With Chronic Inflammatory Demyelinating Polyneuropathy
ClinicalTrials.gov study NCT01184846. IPD Sharing: Not stated. Countries: 5. Publications: 2.
Study to Evaluate Safety and Efficacy of Three Different Dosages of NewGam in Patients With Chronic Inflammatory Demyelinating Poly (Radiculo) Neuropathy
ClinicalTrials.gov study NCT02638207. IPD Sharing: NO. Countries: 9. Publications: 3.
A Study to Assess Long-term Safety, Tolerability and Efficacy of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
ClinicalTrials.gov study NCT04051944. IPD Sharing: YES. Countries: 8. Publications: 1.
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Treatment With Subcutaneous Immunoglobulin (IgPro20)
ClinicalTrials.gov study NCT01545076. IPD Sharing: Not stated. Countries: 16. Publications: 2.
A Study to Assess the Efficacy, Safety and Tolerability of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
ClinicalTrials.gov study NCT03861481. IPD Sharing: YES. Countries: 8. Publications: 0.
Proof-of-concept Study for SAR445088 in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
ClinicalTrials.gov study NCT04658472. IPD Sharing: YES. Countries: 10. Publications: 1.
A Study to Assess the Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the
ClinicalTrials.gov study NCT04281472. IPD Sharing: UNDECIDED. Countries: 25. Publications: 1.
ACALA-R In Predominantly Demyelinating IgM Mediated Neuropathy
ClinicalTrials.gov study NCT05065554. IPD Sharing: YES. Countries: 1. Publications: 1.
SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study
ClinicalTrials.gov study NCT02967679. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Gray Matter Demyelination in Primary Progressive MS at 7T
ClinicalTrials.gov study NCT04977622. IPD Sharing: NO. Countries: 1. Publications: 11.
A Study of HyQvia and Gammagard Liquid (Kiovig) in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
ClinicalTrials.gov study NCT02549170. IPD Sharing: YES. Countries: 22. Publications: 0.
A Study Investigating Intravenous Human Normal Immune Globulin (IGIV) 10% in Subjects With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
ClinicalTrials.gov study NCT06752356. IPD Sharing: YES. Countries: 1. Publications: 1.
Analysis of the Epidemiology, Clinical Presentation and Therapy as Well as Therapy-associated Risk of Demyelination Syndrome in Patients With Profound Hyponatremia in the Emergency Department
ClinicalTrials.gov study NCT06781710. IPD Sharing: NO. Countries: 1. Publications: 0.
Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects
ClinicalTrials.gov study NCT04699747. IPD Sharing: NO. Countries: 1. Publications: 1.
Intravenous Immunoglobulin (IVIg) for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
ClinicalTrials.gov study NCT00001287. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy
ClinicalTrials.gov study NCT06065670. IPD Sharing: NO. Countries: 1. Publications: 5.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.