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140 results for “dentate”
Capacitance clamp demonstration in rat dentate gyrus granule cells
<p>Dataset for a demonstration of the capacitance clamp, a variant of the dynamic clamp technique, which allows to virtually modify the capacitance of a biological neuron (or any electrically excitable cell).</p> <p>Code for analysis and further explanations will be made available. </p>
Fig. 12 in Revision of the aperturally dentate Charopidae (Gastropoda: Stylommatophora) of southern Africa - genus Afrodonta s. lat., with description of five new genera, twelve new species and one new subspecies
Fig. 12. Shells of Costulodonta gen. nov. species. A–D. C. pluridens gen. et sp. nov., holotype, diameter 1.8 mm (NMSA V5920/T4267). E–G. C. trilamellaris (Melvill & Ponsonby, 1908) gen. et comb. nov., paralectotype, Dargle, KwaZulu-Natal, diameter 1.45 mm (NMSA 2181/T624).
Fig. 11 in Revision of the aperturally dentate Charopidae (Gastropoda: Stylommatophora) of southern Africa - genus Afrodonta s. lat., with description of five new genera, twelve new species and one new subspecies
Fig. 11. Distribution of Costulodonta gen. nov. species. C. acinaces (Connolly, 1933) gen. et comb. nov. (green square), C. bidens gen. et sp. nov. (turquoise squares), C. burnupi (Connolly, 1933) gen. et comb. nov. (orange square) C. pluridens gen. et sp. nov. (pink squares), C. trilamellaris (Melvill & Ponsonby, 1908) gen. et comb. nov. (royal blue square). Contour at 1000 m.
Fig. 9 in Revision of the aperturally dentate Charopidae (Gastropoda: Stylommatophora) of southern Africa - genus Afrodonta s. lat., with description of five new genera, twelve new species and one new subspecies
Fig. 9. Distribution of Amatholedonta bimunita (Connolly, 1939) gen. et comb. nov. (green circles), Am. fordycei gen. et sp. nov. (blue circles) and Biomphalodonta forticostata gen. et sp. nov. (orange squares). Contour at 1000 m.
Fig. 8 in Revision of the aperturally dentate Charopidae (Gastropoda: Stylommatophora) of southern Africa - genus Afrodonta s. lat., with description of five new genera, twelve new species and one new subspecies
Fig. 8. Shells of Amatholedonta gen. nov. and Biomphalodonta gen. nov. species. A–D. Amatholedonta bimunita (Connolly, 1939) gen. et comb. nov., Hogsback, E. Cape, diameter 2.0 mm (NMSA W6658). E–H. Am. fordycei gen. et sp. nov., holotype, diameter 1.84 mm (NMSA W6668/T4270). I–L. Biomphalodonta forticostata gen. et sp. nov., holotype, diameter 2.13 mm (NMSA V6949/T4261). M–O. B. forticostata gen. et sp. nov., paratype, large specimen, diameter 2.7 mm (NMSA V4886/T4262).
Fig. 7 in Revision of the aperturally dentate Charopidae (Gastropoda: Stylommatophora) of southern Africa - genus Afrodonta s. lat., with description of five new genera, twelve new species and one new subspecies
Fig. 7. Shells of Afrodonta species. A–D. Afrodonta pentodon sp. nov., holotype, diameter 1.45 mm (NMSA V6950/T4239). E–G. Afrodonta unilamellaris Connolly, 1933, Mfongosi, KwaZulu-Natal, diameter 1.52 mm (NMSA A9186).
Molecular and electrophysiological features of GABAergic neurons in the dentate gyrus reveal limited homology with cortical interneurons
<p>GABAergic interneurons tend to diversify into similar classes across telencephalic regions. However, it remains unclear whether the electrophysiological and molecular properties commonly used to define these classes are discriminant in the hilus of the dentate gyrus. Here, using patch-clamp combined with single cell RT-PCR, we compare the relevance of commonly used electrophysiological and molecular features for the clustering of GABAergic interneurons sampled from the mouse hilus and primary sensory cortex. While unsupervised clustering groups cortical interneurons into well-established classes, it fails to provide a convincing partition of hilar interneurons. Statistical analysis based on resampling indicates that hilar and cortical GABAergic interneurons share limited homology. While our results do not invalidate the use of classical molecular marker in the hilus, they indicate that classes of hilar interneurons defined by the expression of molecular markers do not exhibit strongly discriminating electrophysiological properties.</p>
Text-fig. 40. Scanning electron microscope (SEM) images of monocolpate pollen of Eckhartiopsis parva gen. et sp. nov. from an anther; Torres Vedras locality, Portugal. a) Holotype; elongated anther that yielded the pollen in this Text-figure; b–e) Pollen grains showing dense reticulate tectum supported by short columellae that are only loosely attached to the smooth surface of the foot layer: note dentate orbicules on inner surface of anther wall (b, arrowhead); f) Reticulate tectum showing smooth muri with small adhering orbicules (arrowhead); g) Pollen grains showing one in which the reticulum has been lost exposing the smooth surface of the foot layer; h) Fractured pollen wall showing reticulum, short columellae and thick foot layer; note granules on the inner surface of the apertural region (arrow). Specimen, TV39-S170217 (holotype). Scale bars 300 Μm (a), 6 Μm (b–e, g), 3 Μm (f, h). in The Early Cretaceous Mesofossil Flora Of Torres Vedras (Ne Of Forte Da Forca), Portugal: A Palaeofloristic Analysis Of An Early Angiosperm Community
Text-fig. 40. Scanning electron microscope (SEM) images of monocolpate pollen of Eckhartiopsis parva gen. et sp. nov. from an anther; Torres Vedras locality, Portugal. a) Holotype; elongated anther that yielded the pollen in this Text-figure; b–e) Pollen grains showing dense reticulate tectum supported by short columellae that are only loosely attached to the smooth surface of the foot layer: note dentate orbicules on inner surface of anther wall (b, arrowhead); f) Reticulate tectum showing smooth muri with small adhering orbicules (arrowhead); g) Pollen grains showing one in which the reticulum has been lost exposing the smooth surface of the foot layer; h) Fractured pollen wall showing reticulum, short columellae and thick foot layer; note granules on the inner surface of the apertural region (arrow). Specimen, TV39-S170217 (holotype). Scale bars 300 Μm (a), 6 Μm (b–e, g), 3 Μm (f, h).
Text-fig. 37. Scanning electron microscope (SEM) images of anthers and monocolpate pollen of Eckhartia brevicolumella gen. et sp. nov. from stamen fragment; Torres Vedras locality, Portugal. a) Dithecate, tetrasporangiate anther partially split along the elongated sporangia; b) Dithecate, tetrasporangiate anther; c) Holotype; distal view of pollen grain from holotype showing the long colpus with a distinct margin and a heterobrochate reticulum; d) Distal view of pollen grain from a stamen fragment showing long colpus, colpus margin and heterobrochate reticulum; e) Inner surface of anther wall from stamen fragment showing densely spaced dentate orbicules; f) Lateral view of pollen grains from stamen showing the psilate to foveolate-microreticulate colpus margin; g) Detail of pollen grain from holotype showing the slightly rounded profile of the muri, the short, densely spaced columellae and the dentate orbicules. Specimens, TV44-S136662 (a), TV44-S149204 (b), TV44-S136760 (holotype; c, g), TV44-S148021 (d, e), TV44-S136752 (f). Scale bars 300 Μm (a, b), 6 Μm (c, d, f), 3 Μm (e, g). in The Early Cretaceous Mesofossil Flora Of Torres Vedras (Ne Of Forte Da Forca), Portugal: A Palaeofloristic Analysis Of An Early Angiosperm Community
Text-fig. 37. Scanning electron microscope (SEM) images of anthers and monocolpate pollen of Eckhartia brevicolumella gen. et sp. nov. from stamen fragment; Torres Vedras locality, Portugal. a) Dithecate, tetrasporangiate anther partially split along the elongated sporangia; b) Dithecate, tetrasporangiate anther; c) Holotype; distal view of pollen grain from holotype showing the long colpus with a distinct margin and a heterobrochate reticulum; d) Distal view of pollen grain from a stamen fragment showing long colpus, colpus margin and heterobrochate reticulum; e) Inner surface of anther wall from stamen fragment showing densely spaced dentate orbicules; f) Lateral view of pollen grains from stamen showing the psilate to foveolate-microreticulate colpus margin; g) Detail of pollen grain from holotype showing the slightly rounded profile of the muri, the short, densely spaced columellae and the dentate orbicules. Specimens, TV44-S136662 (a), TV44-S149204 (b), TV44-S136760 (holotype; c, g), TV44-S148021 (d, e), TV44-S136752 (f). Scale bars 300 Μm (a, b), 6 Μm (c, d, f), 3 Μm (e, g).
Molecular and electrophysiological features of GABAergic neurons in the dentate gyrus reveal limited homology with cortical interneurons
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Adult-born granule cells improve stimulus encoding and discrimination in the dentate gyrus
<p>Heterogeneity plays an important role in diversifying neural responses to support brain function. Adult neurogenesis provides the dentate gyrus with a heterogeneous population of granule cells (GCs) that were born and developed their properties at different times. Immature GCs have distinct intrinsic and synaptic properties than mature GCs and are needed for correct encoding and discrimination in spatial tasks. How immature GCs enhance the encoding of information to support these functions is not well understood. Here, we record the responses to fluctuating current injections of GCs of different ages to study how they encode stimuli. Immature GCs produce unreliable responses compared to mature GCs, exhibiting imprecise spike timings across repeated stimulation. We use a statistical model to describe the stimulus-response transformation performed by GCs of different ages. We fit this model to the data and obtain parameters that capture GCs encoding properties. Parameter values from this fit reflect the maturational differences of the population and indicate that immature GCs perform a differential encoding of stimuli. To study how this age heterogeneity influences encoding by a population, we perform stimulus decoding using populations that contain GCs of different ages. We find that, despite their individual unreliability, immature GCs enhance the fidelity of the signal encoded by the population and improve the discrimination of similar time dependent stimuli. Thus, the observed heterogeneity confers the population with enhanced encoding capabilities.</p>
Adiponectin rescues synaptic plasticity in the dentate gyrus of a mouse model of fragile X syndrome
<p>Fragile X Syndrome (FXS) is the most common inherited cause of intellectual disability and is the leading known single-gene cause of autism spectrum disorder. FXS patients display varied behavioural deficits that include mild to severe cognitive impairments in addition to mood disorders. Currently, there is no cure for this condition, however, there is an emerging focus on therapies that inhibit mTOR-dependent protein synthesis due to the clinical effectiveness of metformin for alleviating some behavioural symptoms in FXS. Adiponectin (APN) is a neurohormone that is released by adipocytes and provides an alternative means to inhibit mTOR activation in the brain. In these studies, we show that <em>Fmr1</em> KO mice, like FXS patients, show reduced levels of circulating APN, and that both LTP and LTD in the DG (dentate gyrus) are impaired. Brief (20 min) incubation of hippocampal slices in APN (50 nM) was able to rescue both LTP and LTD in the DG and increased both the surface expression and phosphorylation of GluA1 receptors. These results provide evidence for reduced adiponectin levels in FXS playing a role in decreasing bidirectional synaptic plasticity and show that therapies that enhance adiponectin levels may have therapeutic potential for this and related conditions.</p>
Dietary Flavanols and Dentate Gyrus Function
ClinicalTrials.gov study NCT02312310. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Electrical Stimulation of the Dentate Nucleus for Upper Extremity Hemiparesis Due to Ischemic Stroke
ClinicalTrials.gov study NCT02835443. IPD Sharing: NO. Countries: 1. Publications: 1.
Data from: Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques
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Adult-born granule cells improve stimulus encoding and discrimination in the dentate gyrus
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Synchronous activity patterns in the dentate gyrus during immobility
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Adiponectin rescues synaptic plasticity in the dentate gyrus of a mouse model of fragile X syndrome
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FIGURE 7. Brownlowia latifiana. A. Leaves glabrous, abaxial view. B. Twigs sparsely dentate-lepidote. C. Petiole sparsely dentatelepidote. D in Brownlowia latifiana (Malvaceae-Brownlowioideae), a new species from Terengganu, Peninsular Malaysia
FIGURE 7. Brownlowia latifiana. A. Leaves glabrous, abaxial view. B. Twigs sparsely dentate-lepidote. C. Petiole sparsely dentatelepidote. D. Inflorescences and flower buds densely stellate-lepidote and dentate-lepidote. E. Tricolpate flattened Tilia-type pollen, polar view. F. Reticulate sexine ornamentation with verrucate mount in the centre of pollen, polar view (A from Y.C. Chan & C.L. Lim FRI 65055; B−F from L.E. Teo & W. Emmanuel KL 4797).
Raw neural codes and binsizes for the paper 'Robust and consistent measures of pattern separation based on information theory and demonstrated in the dentate gyrus'
<p>Raw optimal spiking codes and binsizes that maximise information theoretic quantities for the figures of the paper 'Robust and consistent measures of pattern separation based on information theory and demonstrated in the dentate gyrus' (PLoS Comput Biol. 2024 Feb 20;20(2):e1010706) . Additional data will be added in the coming months.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.