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ShareScore release 0.9.0
Dataset results
57 results for “developmental coordination”
Effectiveness of the COOP Group Approach for Children With Developmental Coordination Disorder (DCD)
ClinicalTrials.gov study NCT05231486. IPD Sharing: YES. Countries: 1. Publications: 1.
Achieving My Potential: A Randomized, Controlled Trial of a Telephone-Based Developmental Care Coordination System
ClinicalTrials.gov study NCT04118452. IPD Sharing: YES. Countries: 1. Publications: 1.
Asymmetric evolution of protein domains in the leucine-rich repeat receptor-like kinase (LRR-RLK) family of plant developmental coordinators
<p><span>The coding sequences of developmental genes are expected to be conserved over deep time, with cis-regulatory change driving the modulation of gene function. In contrast, proteins with roles in defense are expected to evolve rapidly, in molecular arms races with pathogens. However, some gene families include both developmental and defense genes. In these families, do the tempo and mode of evolution differ between developmental and defense genes, despite shared ancestry and structure? The leucine-rich repeat receptor-like kinase (LRR-RLKs) protein family includes many members with roles in plant development and defense, thus providing an ideal system for answering this question. LRR-RLKs are receptors that traverse plasma membranes. LRR domains bind extracellular ligands, RLK domains initiate intracellular signaling cascades in response to ligand binding. In LRR-RLKs with roles in defense, LRR domains evolve faster than RLK domains. To determine whether this asymmetry extends to developmental LRR-RLKs, we assessed evolutionary rates and tested for selection acting on eleven clades of LRR-RLK proteins, using deeply sampled protein trees. To assess functional evolution, we performed heterologous complementation assays using <em>Arabidopsis thaliana</em> (arabidopsis) LRR-RLK mutants. We found that the LRR domains of developmental LRR-RLK proteins evolved faster than their cognate RLK domains. LRR-RLKs with roles in development and defense had strikingly similar patterns of molecular evolution. Heterologous transformation experiments revealed that the evolution of developmental LRR-RLKs likely involves multiple mechanisms, including changes to cis-regulation, coding sequence evolution, and escape from adaptive conflict. Our results indicate similar evolutionary pressures acting on developmental and defense signaling proteins, despite divergent organismal functions. In addition, deep understanding of the molecular evolution of developmental receptors can help guide targeted genome engineering in agriculture.</span></p>
Social Skills in Children With Developmental Coordination Disorder (DCD)
ClinicalTrials.gov study NCT05092893. IPD Sharing: NO. Countries: 1. Publications: 1.
The Effects of a Group-based Gaze Training Intervention for Children With Developmental Coordination Disorder
ClinicalTrials.gov study NCT02904980. IPD Sharing: NO. Countries: 1. Publications: 2.
Effects of CO-OP Approach on Activity and Participation of Brazilian Children With Developmental Coordination Disorder
ClinicalTrials.gov study NCT02893852. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Influence of Sensory Stimulation on Sensory Parameters and Motor Function in Children With Developmental Coordination Disorder
ClinicalTrials.gov study NCT06959329. IPD Sharing: UNDECIDED. Countries: 2. Publications: 9.
Functional Movement-power Training for Children With Developmental Coordination Disorder: A Randomised Controlled Trial
ClinicalTrials.gov study NCT02393404. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of a Highly Intensive Balance Therapy Camp in Children With Developmental Coordination Disorder
ClinicalTrials.gov study NCT07096817. IPD Sharing: YES. Countries: 1. Publications: 1.
Rhythmic Motor Learning in Children With Developmental Coordination Disorders
ClinicalTrials.gov study NCT03150784. IPD Sharing: NO. Countries: 1. Publications: 2.
Ambulatory Screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).
ClinicalTrials.gov study NCT04122820. IPD Sharing: NO. Countries: 1. Publications: 1.
Effectiveness of Motor Imagery and Task-oriented Training in Children With Developmental Coordination Disorder
ClinicalTrials.gov study NCT04176159. IPD Sharing: YES. Countries: 1. Publications: 10.
Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD)
ClinicalTrials.gov study NCT02393729. IPD Sharing: Not stated. Countries: 1. Publications: 2.
ImpACT for Developmental Coordination Disorder
ClinicalTrials.gov study NCT05499143. IPD Sharing: NO. Countries: 1. Publications: 1.
Effects of Task-Oriented Intervention in Children With Developmental Coordination Disorder
ClinicalTrials.gov study NCT06736119. IPD Sharing: NO. Countries: 1. Publications: 1.
Asymmetric evolution of protein domains in the leucine-rich repeat receptor-like kinase (LRR-RLK) family of plant developmental coordinators
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Data from: Coordination of wing and whole body development at developmental milestones ensures robustness against environmental and physiological perturbations
Development produces correctly patterned tissues under a wide range of conditions that alter the rate of development in the whole body. We propose two hypotheses through which tissue patterning could be coordinated with whole body development to generate this robustness. Our first hypothesis states that tissue patterning is tightly coordinated with whole body development over time. The second hypothesis is that tissue patterning aligns at developmental milestones. To distinguish between our two hypotheses, we developed a staging scheme for the wing imaginal discs of Drosophila larvae using the expression of canonical patterning genes, linking our scheme to three whole body developmental events, moulting, larval wandering and pupariation. We used our scheme to explore how the progression of pattern changes when developmental time is altered either by changing temperature or by altering the timing of hormone synthesis that drives developmental progression. We found the expression pattern in the wing disc always aligned at moulting and pupariation, indicating that these key developmental events represent milestones. Between these milestones, the progression of pattern showed greater variability in response to changes in temperature and alterations in physiology. Furthermore, our data showed that discs from wandering larvae had greater variability in their patterning stage. Thus, for wing disc patterning wandering does not appear to be a developmental milestone. Our findings reveal that tissue patterning remains robust against environmental and physiological perturbations by aligning at developmental milestones. Furthermore, our work provides an important glimpse into how the development of individual tissues is coordinated with the body as a whole.
Efficacy of the CO-OP Approach With Brazilian Children With Developmental Coordination Disorder
ClinicalTrials.gov study NCT03112746. IPD Sharing: NO. Countries: 0. Publications: 6.
Trampoline Exercises Children With Developmental Coordination Disorder
ClinicalTrials.gov study NCT04694352. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Coordination of wing and whole body development at developmental milestones ensures robustness against environmental and physiological perturbations
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.