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1,908 results for “dexamethasone”
Identification of Genes Regulating Dexamethasone Resistance and Prognostic Model Development in Acute Lymphoblastic Leukemia
<p>This study investigates the mechanisms of dexamethasone resistance in acute lymphoblastic leukemia (ALL) and presents a prognostic model to predict patient outcomes and immunotherapy responses. By analyzing gene expression data, we identified autophagy-related genes associated with dexamethasone resistance, particularly focusing on STK38L’s role in modulating autophagy via ULK1. Our results reveal that high STK38L expression enhances dexamethasone resistance by promoting autophagy markers LC3II/LC3I and beclin-1. This study provides valuable insights into the molecular basis of dexamethasone resistance and highlights STK38L as a potential biomarker and therapeutic target for improving ALL treatment strategies.</p>
Study of Panobinostat in Combination With Bortezomib and Dexamethasone in Japanese Patients With Relapsed/Refractory Multiple Myeloma
ClinicalTrials.gov study NCT02290431. IPD Sharing: YES. Countries: 1. Publications: 1.
Multinational Clinical Study Comparing Isatuximab, Pomalidomide, and Dexamethasone to Pomalidomide and Dexamethasone in Refractory or Relapsed and Refractory Multiple Myeloma Patients
ClinicalTrials.gov study NCT02990338. IPD Sharing: YES. Countries: 24. Publications: 8.
Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis
ClinicalTrials.gov study NCT01659658. IPD Sharing: YES. Countries: 15. Publications: 2.
A Study of Ixazomib+Daratumumab+Dexamethasone (IDd) in Relapsed and/or Refractory Multiple Myeloma (RRMM)
ClinicalTrials.gov study NCT03439293. IPD Sharing: YES. Countries: 6. Publications: 0.
A Study of Ixazomib Plus Lenalidomide and Dexamethasone in Adult Japanese Participants With Relapsed and/or Refractory Multiple Myeloma
ClinicalTrials.gov study NCT02917941. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study to Evaluate the Efficacy and Safety of Ixazomib in Combination With Lenalidomide and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma Initially Treated With an Inject
ClinicalTrials.gov study NCT03416374. IPD Sharing: YES. Countries: 1. Publications: 1.
Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity
ClinicalTrials.gov study NCT04879823. IPD Sharing: NO. Countries: 1. Publications: 11.
SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM
ClinicalTrials.gov study NCT05405166. IPD Sharing: YES. Countries: 21. Publications: 1.
IXAZOMIB Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Newly Diagnosed Multiple Myeloma
ClinicalTrials.gov study NCT01850524. IPD Sharing: YES. Countries: 7. Publications: 1.
Multinational Clinical Study Comparing Isatuximab, Carfilzomib And Dexamethasone To Carfilzomib And Dexamethasone In Relapse And/Or Refractory Multiple Myeloma Patients
ClinicalTrials.gov study NCT03275285. IPD Sharing: YES. Countries: 16. Publications: 10.
Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study
ClinicalTrials.gov study NCT04168112. IPD Sharing: NO. Countries: 1. Publications: 13.
A Study in Relapsed and/or Refractory Multiple Myeloma Patients Treated With Ixazomib Plus Lenalidomide and Dexamethasone
ClinicalTrials.gov study NCT03433001. IPD Sharing: YES. Countries: 1. Publications: 2.
A Study of Ixazomib, Given With Dexamethasone in Adults With Multiple Myeloma
ClinicalTrials.gov study NCT03170882. IPD Sharing: YES. Countries: 18. Publications: 1.
E-PRISM: Phase II Trial of Elotuzumab Lenalidomide and Dexamethasone in High-Risk Smoldering Multiple Myeloma
ClinicalTrials.gov study NCT02279394. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup
ClinicalTrials.gov study NCT03705273. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma
ClinicalTrials.gov study NCT04251715. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of LY3039478 in Combination With Dexamethasone in Participants With T-ALL/T-LBL
ClinicalTrials.gov study NCT02518113. IPD Sharing: YES. Countries: 5. Publications: 1.
Phase 1 Pharmacokinetic Study of Oral Ixazomib Plus Lenalidomide and Dexamethasone in Adult Asian Participants With Relapsed and/or Refractory Multiple Myeloma
ClinicalTrials.gov study NCT01645930. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Safety and Efficacy of Dexamethasone (OZURDEX®) Intravitreal Implant in Korea
ClinicalTrials.gov study NCT01976650. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.