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8 results for “differential cost”
Data from: Differential host responses to parasitism shape divergent fitness costs of infection
Fitness costs of infection are fundamental to understanding the ecology and evolution of host-parasite interactions. However, these costs, and particularly their underlying mechanisms, are challenging to evaluate in wild populations. Here, we quantified total and species-specific costs of gastrointestinal worms on African buffalo, by combining the power of an anthelmintic treatment experiment that perturbed the entire worm community with a longitudinal study that tracked the two most dominant community members. Reducing all worms improved buffalo body condition, which was strongly associated with increases in survival and reproduction. Species-specific analyses revealed that condition-mediated fitness costs of infection differed between parasite species. Hosts that gained the blood-sucking worm Haemonchus, lost condition, and this loss may have been mediated by reductions in forage intake. Hosts that resisted Haemonchus by elevating IL-4 and eosinophil immune defences were able to reduce their parasite loads and gain back condition. Conversely, hosts that gained Cooperia, a less pathogenic worm, gained condition and had higher survival and reproductive success. Elevating immune defences had no effect on Cooperia abundance. Coupled with the positive relationship observed between Cooperia and host condition, our data suggest that hosts might benefit from tolerating Cooperia rather than incurring the costs of resistance. Overall, our study reveals that differential host responses to parasites play a key role in mediating the costs of infection.
Data from: Differential host responses to parasitism shape divergent fitness costs of infection
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Patterns of convergence and bound constraint violation in Differential Evolution on SBOX-COST benchmarking suite
<p>The data sets contain information collected during runs of :</p> <ul> <li>DE/rand/1/bin (D=20, N=50, F=0.5, CR=0.5);</li> <li>L-SHADE(D=20, N_init = 18*D)</li> </ul> <p>on all 24 test functions from instances 1-5 and 101-110 from the SBOX-COST and BBOB test suites.</p> <ul> <li>For the <strong>analysis with fixed budget</strong>, the number of independent runs was 30 and the stopping condition NFE (number of function evaluations) was 5000*D.</li> <li>For the <strong>convergence analysis</strong>, 5 independent runs were used for instances 1-5 of the 24 test functions and there was a combined stopping condition consisting of NFE=10000*D, population size larger than 10, variance of the population greater than 10^(-15) and the difference between the global best optimum and known best greater than 10^(-8).</li> </ul> <p> </p> <p> </p>
Data from: Differential dispersal costs and sex-biased dispersal distance in a cooperatively breeding bird
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Data from: Evolution of male age-specific reproduction under differential risks and causes of death: males pay the cost of high female fitness
Classic theories of ageing evolution predict that increased extrinsic mortality due to an environmental hazard selects for increased early reproduction, rapid ageing and short intrinsic lifespan. Conversely, emerging theory maintains that when ageing increases susceptibility to an environmental hazard, increased mortality due to this hazard can select against ageing in physiological condition and prolong intrinsic lifespan. However, evolution of slow ageing under high-condition-dependent mortality is expected to result from reallocation of resources to different traits and such reallocation may be hampered by sex-specific trade-offs. Because same life-history trait values often have different fitness consequences in males and females, sexually antagonistic selection can preserve genetic variance for lifespan and ageing. We previously showed that increased condition-dependent mortality caused by heat shock leads to evolution of long-life, decelerated late-life mortality in both sexes and increased female fecundity in the nematode, Caenorhabditis remanei. Here, we used these cryopreserved lines to show that males evolving under heat shock suffered from reduced early-life and net reproduction, while mortality rate had no effect. Our results suggest that heat-shock resistance and associated long-life trade-off with male, but not female, reproduction and therefore sexually antagonistic selection contributes to maintenance of genetic variation for lifespan and fitness in this population.
Data from: Evolution of male age-specific reproduction under differential risks and causes of death: males pay the cost of high female fitness
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BART-Seq: cost-effective massively parallelized targeted sequencing for genomics, transcriptomics, and single cell analysis [Differentiation]
GEO Series GSE130420. Homo sapiens. 3 samples. Type: Other; Expression profiling by high throughput sequencing.
Highly reproducible and cost-effective one-pot organoid differentiation using a novel platform based on PF-127 triggered spheroid assembly
GEO Series GSE240256. Homo sapiens. 62 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.