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ShareScore release 0.9.0
Dataset results
15 results for “disseminated intravascular coagulation”
Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation
ClinicalTrials.gov study NCT02654561. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Data from: Can recombinant human thrombomodulin increase survival among patients with severe septic-induced disseminated intravascular coagulation: a single-centre, open-label, randomised controlled trial
Objective: To determine whether treatment with recombinant human thrombomodulin (rhTM) increases survival among severe septic patients with sepsis-induced disseminated intravascular coagulation (DIC) Design: Single-center, open-label, randomized controlled trial Setting: Single tertiary hospital Participant: 92 severe septic patients with sepsis-induced DIC Interventions: Patients with DIC scores ≥4, as defined by the Japanese Association of Acute Medicine, were diagnosed with DIC. Randomization was performed by the envelope method. The treatment group (rhTM group, n = 47) was intravenously treated with rhTM within 24 h of admission (day 0), and the control group (n = 45) did not receive any anti-coagulants, except in cases of deep venous thrombosis and pulmonary embolism. Primary and secondary measurements: Data were collected on days 0 (admission), 1, 2, 3, 5, 7, and 10. The primary outcome was survival at 28 and 90 days. The secondary endpoints comprised changes in DIC scores, platelet counts, D-dimer, antithrombin III (ATIII), and C-reactive protein (CRP) levels, and Sequential Organ Failure Assessment (SOFA) scores. All analyses were conducted on an intent-to-treat basis. Main Results: The 28-day survival rates were 84 and 83% in the control and rhTM groups, respectively (p = 0.745, log rank test). The 90-day survival rates were 73% and 72% in the control and rhTM groups, respectively (p = 0.94, log rank test). Meanwhile, the rates of recovery from DIC (<4) were significantly higher in the rhTM group than in the control group (p = 0.001, log rank test). Relative change from baseline of D-dimer levels were significantly lower in the rhTM group than in the control group, on day 3 and 5. Conclusion: rhTM treatment decreased D-dimer levels and facilitated DIC recovery in severe septic patients with sepsis-induced DIC. However, the treatment did not improve survival in this cohort.
Significance of Disseminated Intravascular Coagulation Score in Mortality for Children With Shock
ClinicalTrials.gov study NCT06581172. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Predictive Value of Scoring System in Neonates with Disseminated Intravascular Coagulation
ClinicalTrials.gov study NCT06626880. IPD Sharing: Not stated. Countries: 0. Publications: 6.
Data from: Can recombinant human thrombomodulin increase survival among patients with severe septic-induced disseminated intravascular coagulation: a single-centre, open-label, randomised controlled trial
Open the record for dataset details and reuse information.
International Prospective Registry of Disseminated Intravascular Coagulation
ClinicalTrials.gov study NCT03577015. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study to Learn About the Occurrence of Disseminated Intravascular Coagulation in People With Sepsis and Further Worsening of Sepsis
ClinicalTrials.gov study NCT06986798. IPD Sharing: NO. Countries: 7. Publications: 0.
The Proactive Diagnostic Value of Hemostatic Biomarkers in Disseminated Intravascular Coagulation
ClinicalTrials.gov study NCT05995093. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Pharmacokinetics Study of ART-123 in Disseminated Intravascular Coagulation (DIC) Subjects With Renal Impairment
ClinicalTrials.gov study NCT01704001. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation
ClinicalTrials.gov study NCT00487656. IPD Sharing: Not stated. Countries: 4. Publications: 0.
EVALUATION OF NEUTROPHIL FLUORESCENCE IN PATIENTS WITH DISSEMINATED INTRAVASCULAR COAGULATION ASSOCIATED WITH SEPTIC SHOCK
ClinicalTrials.gov study NCT07039487. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients
ClinicalTrials.gov study NCT06363149. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
An Observational Study to Learn About the Occurrence of Disseminated Intravascular Coagulation Among Adults With Sepsis in Japan
ClinicalTrials.gov study NCT06373159. IPD Sharing: NO. Countries: 1. Publications: 0.
An Observational Study in the United States to Learn How Venous Thromboembolism, Disseminated Intravascular Coagulation, and Sepsis Are Related
ClinicalTrials.gov study NCT06765681. IPD Sharing: NO. Countries: 1. Publications: 0.
4G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic Shock
ClinicalTrials.gov study NCT01211899. IPD Sharing: Not stated. Countries: 0. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.