Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,039
datasets available to search
ShareScore release 0.9.0
Dataset results
1,039 results for “epidermal”
Insights into metabolic changes during epidermal differentiation as revealed by multiphoton microscopy with fluorescence lifetime imaging
<p>Rapid developments in the field of organotypic cultures has generated a growing need for effective quality control measures during tissue development. In this study, we correlate metabolic changes with epidermal differentiation and demonstrate that multiphoton microscopy with fluorescence lifetime imaging (MPM-FLIM) can be applied as a non-invasive approach to monitor epidermal differentiation of keratinocytes with respect to proliferative and differentiated states. Keratinocytes grown at 1.5 mM Ca2+ exhibited increased expression of differentiation markers KRT1 and KRT10 compared to 60 μM Ca2+, and a metabolic shift from glycolysis to mitochondrial respiration. Fitting the fluorescence decay with a biexponential model revealed a decreased relative fraction of intracellular NADH and FAD after high calcium treatment, consistent with increased oxidative phosphorylation. Using these two parameters, the epidermal differentiation process could be monitored over a 96 h period. Implementing discriminating analysis based on k-means clustering generated clusters that correlated well with culturing time, suggesting that this methodology can be employed as part of an automated pipeline for monitoring keratinocyte differentiation.</p>
Altered nanoparticle uptake by lung carcinoma cells when stimulated with epidermal growth factor
<p>This dataset provides the raw data supporting the paper "Altered nanoparticle uptake by lung carcinoma cells when stimulated with epidermal growth factor". The focus of the study was to investigate the uptake of two different sizes of silica NPs and gold NPs in lung epithelial cells A549 in the presence of epidermal growth factor (EGF). </p> <p>The data set includes:</p> <ul> <li>Screening for EGF receptor using western blot and confocal microscopy (Figure 1 and Figure S1)</li> <li>Investigating expression of RAC1/CDC42 proteins upon EGF stimulation using Western blot (Figure 2)</li> <li>Investigating expression of RAC1 gene upon EGF stimulation using RT-qPCR (Figure S2)</li> <li>Evaluating uptake of endocytic markers upon EGF stimulation using confocal laser scanning microscopy (Figure 3, Figure S4) and flow cytometry (Figure 3)</li> <li>Nanoparticle characterization using TEM (Figure 4, Figure S6) and UV-Vis (Figure S5, Figure S6)</li> <li>Evaluating silica nanoparticle uptake upon EGF stimulation using confocal laser scanning microscopy (Figure 5, Figure S8) and flow cytometry (Figure 5)</li> <li>Evaluating gold nanoparticle uptake upon EGF stimulation using dark-field microscopy and ICP-AES (Figure 6)</li> <li>Investigating expression of c-MYC gene upon EGF stimulation using RT-qPCR (Figure 6)</li> <li>Cell viability results, analysed via lactate dehydrogenase assay (Figure S3) and MTS assay (Figure S9)</li> <li>Raw integrated density data from dark-field images (Figure S9)</li> </ul>
Convolutional Neural Net (CNN) models for epigenomic landscapes in epidermal differentiation - Basset architecture, classification and regression
<p>Deep learning models trained on epigenomic landscapes in keratinocyte differentiation. The models are Basset convolutional neural networks (Kelley, et al 2016). The dataset used to train these models can be found at https://doi.org/10.5281/zenodo.4062509. The file `nn.ggr.models.basset.clf.tar.gz` contains 10 cross-validated models that were pretrained using ENCODE-Roadmap trained model weights as initialization weights and also 10 cross-validated models that were initialized with random weights. Similarly, the file `nn.ggr.models.basset.regr.tar.gz` contains 10 cross-validated models that were pretrained using the classification model weights as initialization weights and also 10 cross-validated models that were initialized with random weights.</p>
Analysis of bacteria, inflammation, and exudation in epidermal suction blister wounds reveals dynamic changes during wound healing - Dataset
<p>Dataset for "<strong>Analysis of bacteria, inflammation, and exudation in epidermal suction blister wounds reveals dynamic changes during wound healing</strong>". Data were generated from samples collected to a biobank from suction blister wounds at various timepoints during a clinical trial (<a href="https://clinicaltrials.gov/study/NCT05378997?term=NCT05378997&rank=1"><strong>NCT05378997</strong></a>). Data include concentration of bacteria in swab and dressing fluid samples, neutrophil proteins (HNE, MPO, and HBP), cytokines (IFN-gamma, interleukin IL-1beta, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-13, TNF-alpha) and total protein measured in dressing fluid samples, and bacterial species identified by MALDI-TOF in swab and dressing fluid samples.</p>
Text-fig. 3. SRXTM images of Miranthus elegans gen. et sp. nov.; Mira locality, Portugal. a, b: Volume renderings of flower bud in two different lateral views showing long pedicel, distinct calyx (ca) with almost equiaxial epidermal cells and corolla (co) with nearly smooth surface. c–e: Transverse sections (c, orthoslice xy1500; d, orthoslice xy1760; e, orthoslice xy1850) through flower bud at levels below the anthers showing stamen filaments (yellow) opposite the corolla lobes (co) and smaller staminodes (orange) in Early Flowers Of Primuloid Ericales From The Late Cretaceous Of Portugal And Their Ecological And Phytogeographic Implications
Text-fig. 3. SRXTM images of Miranthus elegans gen. et sp. nov.; Mira locality, Portugal. a, b: Volume renderings of flower bud in two different lateral views showing long pedicel, distinct calyx (ca) with almost equiaxial epidermal cells and corolla (co) with nearly smooth surface. c–e: Transverse sections (c, orthoslice xy1500; d, orthoslice xy1760; e, orthoslice xy1850) through flower bud at levels below the anthers showing stamen filaments (yellow) opposite the corolla lobes (co) and smaller staminodes (orange)
Text-fig. 5. SRXTM images of Miranthus elegans gen. et sp. nov.; Mira locality, Portugal. a, b: Transverse sections of flower (a, orthoslice xy0665 close to the apex of placenta; b, orthoslice xy0800 in middle part of placenta) showing remains of calyx with distinct bundles (arrows), ovary wall (ow) and numerous ovules (ov) on the central mushroom-shaped globose placenta (pl) with central column (cc). c: Transverse section of flower (orthoslice xy0620) through perianth and ovary (ow) at a level above the placenta showing ovules (ov) and cellular preservation of the sepal bundles (arrows shown for one sepal); note abaxial surface of sepals with thick-walled epidermal cells, thick cuticle, and fine pointed verrucae. d: Longitudinal section of flower (orthoslice xz0500) showing perigynous position of calyx and semi-inferior ovary (ow, ovary wall) with a central placenta (pl), central column (cc) and numerous ovules (ov); note spiny verrucae on abaxial surface of calyx lobes. Specimens, Mira 100-S153145 (a, b), Mira 100-S170155 (c, d, holotype). Scale bars = 600 µm (a–d). in Early Flowers Of Primuloid Ericales From The Late Cretaceous Of Portugal And Their Ecological And Phytogeographic Implications
Text-fig. 5. SRXTM images of Miranthus elegans gen. et sp. nov.; Mira locality, Portugal. a, b: Transverse sections of flower (a, orthoslice xy0665 close to the apex of placenta; b, orthoslice xy0800 in middle part of placenta) showing remains of calyx with distinct bundles (arrows), ovary wall (ow) and numerous ovules (ov) on the central mushroom-shaped globose placenta (pl) with central column (cc). c: Transverse section of flower (orthoslice xy0620) through perianth and ovary (ow) at a level above the placenta showing ovules (ov) and cellular preservation of the sepal bundles (arrows shown for one sepal); note abaxial surface of sepals with thick-walled epidermal cells, thick cuticle, and fine pointed verrucae. d: Longitudinal section of flower (orthoslice xz0500) showing perigynous position of calyx and semi-inferior ovary (ow, ovary wall) with a central placenta (pl), central column (cc) and numerous ovules (ov); note spiny verrucae on abaxial surface of calyx lobes. Specimens, Mira 100-S153145 (a, b), Mira 100-S170155 (c, d, holotype). Scale bars = 600 µm (a–d).
Text-fig. 7. SEM (a) and SRXTM (b–e) images of Miranthus kvacekii sp. nov.; Mira locality, Portugal. a: Lateral view of flower bud showing corolla lobes extending beyond calyx; note surface of pedicel, calyx and corolla with small equiaxial epidermal cells and indumentum of densely spaced, short stiff trichomes. b, c: Longitudinal sections through floral bud in two directions perpendicular to each other (a, orthoslice yz1024; b, orthoslice xz0950) showing corolla (co), calyx (ca), stamens (st) and semi-inferior ovary with thin ovary wall (ow) and central mushroom-shaped globose placenta (pl) bearing numerous ovules (ov). d, e: Transverse sections through floral bud above placenta (d, orthoslice xy0915; e, orthoslice xy1095) showing calyx (ca), corolla (co), ovary wall (ow) and ovules (ov); yellow outlines indicate the positions of anthers (d) and filaments (e); orange outlines indicate the position of three of the possible staminodes. Specimen, Mira 100-S170157 (a–e, holotype). Scale bars = 600 µm (a–c), 300 µm (d, e). in Early Flowers Of Primuloid Ericales From The Late Cretaceous Of Portugal And Their Ecological And Phytogeographic Implications
Text-fig. 7. SEM (a) and SRXTM (b–e) images of Miranthus kvacekii sp. nov.; Mira locality, Portugal. a: Lateral view of flower bud showing corolla lobes extending beyond calyx; note surface of pedicel, calyx and corolla with small equiaxial epidermal cells and indumentum of densely spaced, short stiff trichomes. b, c: Longitudinal sections through floral bud in two directions perpendicular to each other (a, orthoslice yz1024; b, orthoslice xz0950) showing corolla (co), calyx (ca), stamens (st) and semi-inferior ovary with thin ovary wall (ow) and central mushroom-shaped globose placenta (pl) bearing numerous ovules (ov). d, e: Transverse sections through floral bud above placenta (d, orthoslice xy0915; e, orthoslice xy1095) showing calyx (ca), corolla (co), ovary wall (ow) and ovules (ov); yellow outlines indicate the positions of anthers (d) and filaments (e); orange outlines indicate the position of three of the possible staminodes. Specimen, Mira 100-S170157 (a–e, holotype). Scale bars = 600 µm (a–c), 300 µm (d, e).
Рис. 2. Варианты преΑсказанной Αоменной структуры патогенраспознающих моΛекуΛ гемоцитов моΛΛюсков Planorbarius corneus. a — фибриногенпоΑобные беΛки, b — гаΛектины, c — F-Λектины. УсΛовные обозначения и сокращения, зΑесь и ΑаΛее: горизонтаΛьные красные поΛоски — сигнаΛьный пептиΑ, горизонтаΛьные розовые — обΛасть низкой сΛожности, вертикаΛьные синие поΛоски — трансмембранная обΛасть, FBG — фибриногеновый Αомен, FTP — Αомен фукоΛектина, EGF — Αомен эпиΑермаΛьного фактора роста, EGF_CA — каΛьцийсвязывающий EGF-поΑобный Αомен, PAN_AP — APPLE-поΑобный Αомен, SCAN — обΛасть, богатая Λейцином, GLECT — гаΛактозосвязывающий Λектин, CLECT — Λектин C-типа, Gal-bind — гаΛактозиΑ–связывающий Λектин, ML — MD-2- поΑробный Αомен распознавания ΛипиΑов Fig. 2. Variants of the predicted domain structure of pattern recognition molecules from hemocytes of Planorbarius corneus molluscs. a — fibrinogen-related proteins, b — galectins, c — F-lectins. Symbols and abbreviations (here and further): horizontal red stripes — signal peptide, horizontal pink stripes — a low complexity region, vertical blue stripes — transmembrane region, FBG — fibrinogen-related domain, FTP — fucolectin domain, EGF — epidermal growth factor-like domain, EGF_CA — calcium-binding EGF-like domain, PAN_AP — APPLE-like domain, SCAN — leucine rich region, Apple — APPLE domain, GLECT — galactose-binding lectin, CLECT — C-type lectin, Gal-bind — galactoside-binding lectin, ML — MD-2-related lipid-recognition domain in Pathogen recognition molecules from hemocytes of Planorbarius corneus molluscs (Planorbidae, Pulmonata)
Рис. 2. Варианты преΑсказанной Αоменной структуры патогенраспознающих моΛекуΛ гемоцитов моΛΛюсков Planorbarius corneus. a — фибриногенпоΑобные беΛки, b — гаΛектины, c — F-Λектины. УсΛовные обозначения и сокращения, зΑесь и ΑаΛее: горизонтаΛьные красные поΛоски — сигнаΛьный пептиΑ, горизонтаΛьные розовые — обΛасть низкой сΛожности, вертикаΛьные синие поΛоски — трансмембранная обΛасть, FBG — фибриногеновый Αомен, FTP — Αомен фукоΛектина, EGF — Αомен эпиΑермаΛьного фактора роста, EGF_CA — каΛьцийсвязывающий EGF-поΑобный Αомен, PAN_AP — APPLE-поΑобный Αомен, SCAN — обΛасть, богатая Λейцином, GLECT — гаΛактозосвязывающий Λектин, CLECT — Λектин C-типа, Gal-bind — гаΛактозиΑ–связывающий Λектин, ML — MD-2- поΑробный Αомен распознавания ΛипиΑов Fig. 2. Variants of the predicted domain structure of pattern recognition molecules from hemocytes of Planorbarius corneus molluscs. a — fibrinogen-related proteins, b — galectins, c — F-lectins. Symbols and abbreviations (here and further): horizontal red stripes — signal peptide, horizontal pink stripes — a low complexity region, vertical blue stripes — transmembrane region, FBG — fibrinogen-related domain, FTP — fucolectin domain, EGF — epidermal growth factor-like domain, EGF_CA — calcium-binding EGF-like domain, PAN_AP — APPLE-like domain, SCAN — leucine rich region, Apple — APPLE domain, GLECT — galactose-binding lectin, CLECT — C-type lectin, Gal-bind — galactoside-binding lectin, ML — MD-2-related lipid-recognition domain
Text-fig. 4. Tumidopteris astra sp. nov., holotype GIN 4851/343h, morphology of sori (a, b, c), epidermal structure (e) and the sterile pinna (d; spec. 4851/344). a: partly damaged sorus; b: partly damaged sorus with six sporangia; c: two neighboring sori; d: part of the sterile pinna; e: costal epiderma. Scale 500 Μm (a, b, c), 1 cm (d), 200 Μm (e). in A New Species Of The Genus Tumidopteris Naugolnykh From The Permian Of The Pechora Cis-Urals, Russia
Text-fig. 4. Tumidopteris astra sp. nov., holotype GIN 4851/343h, morphology of sori (a, b, c), epidermal structure (e) and the sterile pinna (d; spec. 4851/344). a: partly damaged sorus; b: partly damaged sorus with six sporangia; c: two neighboring sori; d: part of the sterile pinna; e: costal epiderma. Scale 500 Μm (a, b, c), 1 cm (d), 200 Μm (e).
Text-fig. 54. Scanning electron microscope (SEM; a–e, g, h) and synchrotron x-ray microscopy (SRXTM; f, i) images of unnamed angiosperm fruits and seeds; Torres Vedras locality, Portugal. a) Follicle sp. 1, narrow elongate follicle with sessile and decurrent stigma; b) Follicle sp. 2, broad, dehisced follicle with elongate and transverse fibers lining the locule; c) Angiosperm seed sp. 1 with thin, smooth seed coat; d) Angiosperm seed sp. 2 with verrucate seed coat; e) Angiosperm seed sp. 3 with exotestal and foveolate seed coat; f) Angiosperm seed sp. 4 with smooth seed coat; g, h) Angiosperm seed sp. 5 with raised epidermal cells forming a reticulate pattern; i) Wedge-shaped angiosperm fruit with remains of floral parts near apex. Specimens, TV43-S136726 (a), TV44-S148144 (b), TV43-S170074 (c), TV43-S136747 (d), TV43-S170073 (e), TV38-S174615 (f), TV44-S148003 (g), TV44-S148004 (h), TV43-S174685 (i). Scale bars 300 Μm (a–i). in The Early Cretaceous Mesofossil Flora Of Torres Vedras (Ne Of Forte Da Forca), Portugal: A Palaeofloristic Analysis Of An Early Angiosperm Community
Text-fig. 54. Scanning electron microscope (SEM; a–e, g, h) and synchrotron x-ray microscopy (SRXTM; f, i) images of unnamed angiosperm fruits and seeds; Torres Vedras locality, Portugal. a) Follicle sp. 1, narrow elongate follicle with sessile and decurrent stigma; b) Follicle sp. 2, broad, dehisced follicle with elongate and transverse fibers lining the locule; c) Angiosperm seed sp. 1 with thin, smooth seed coat; d) Angiosperm seed sp. 2 with verrucate seed coat; e) Angiosperm seed sp. 3 with exotestal and foveolate seed coat; f) Angiosperm seed sp. 4 with smooth seed coat; g, h) Angiosperm seed sp. 5 with raised epidermal cells forming a reticulate pattern; i) Wedge-shaped angiosperm fruit with remains of floral parts near apex. Specimens, TV43-S136726 (a), TV44-S148144 (b), TV43-S170074 (c), TV43-S136747 (d), TV43-S170073 (e), TV38-S174615 (f), TV44-S148003 (g), TV44-S148004 (h), TV43-S174685 (i). Scale bars 300 Μm (a–i).
Text-fig. 18. Scanning electron microscope (SEM) images of a fruit of Canrightia sp. with associated pollen; Torres Vedras locality, Portugal. a) Fruit in lateral view showing prominent cavities in the fruit wall formed by the scattered oil bodies and the broad hypanthium fused to the base of the fruit (arrowhead); b) Fruit surface showing epidermal cells and the scattered oil cells embedded in the fruit wall (arrowheads); c) Cluster of monocolpate pollen grains in the probable stigmatic region of the fruit; d) Pollen grains showing the long colpus and semitectate-reticulate pollen wall; e) Pollen wall showing the reticulum with large and small lumina, and scattered, compressed columellae supporting the smooth muri. Specimen, TV142-S170213. Scale bars 300 Μm (a), 100 Μm (b), 30 Μm (c), 6 Μm (d), 1 Μm (e). in The Early Cretaceous Mesofossil Flora Of Torres Vedras (Ne Of Forte Da Forca), Portugal: A Palaeofloristic Analysis Of An Early Angiosperm Community
Text-fig. 18. Scanning electron microscope (SEM) images of a fruit of Canrightia sp. with associated pollen; Torres Vedras locality, Portugal. a) Fruit in lateral view showing prominent cavities in the fruit wall formed by the scattered oil bodies and the broad hypanthium fused to the base of the fruit (arrowhead); b) Fruit surface showing epidermal cells and the scattered oil cells embedded in the fruit wall (arrowheads); c) Cluster of monocolpate pollen grains in the probable stigmatic region of the fruit; d) Pollen grains showing the long colpus and semitectate-reticulate pollen wall; e) Pollen wall showing the reticulum with large and small lumina, and scattered, compressed columellae supporting the smooth muri. Specimen, TV142-S170213. Scale bars 300 Μm (a), 100 Μm (b), 30 Μm (c), 6 Μm (d), 1 Μm (e).
Text-fig. 46. Scanning electron microscope (SEM) images of "Rugulate fruit"; Catefica locality, Portugal. a, b) Lateral (a) and ventral (b) views of a rugulate fruit showing the short extension of the sessile stigma at the apex (arrows); c) Irregular surface of fruit that probably reflects an irregular endocarp; note the isodiametric outlines of the epidermal cells; d) Semi-tectate reticulate pollen grains embedded in the remains of a secretion on the stigmatic surface. Specimen, Catefica 154-S101291 (a–d). Scale bars = 300 Μm (a, b), 100 Μm (c), 6 Μm (d). in The Early Cretaceous Mesofossil Flora Of Catefica, Portugal: Angiosperms
Text-fig. 46. Scanning electron microscope (SEM) images of "Rugulate fruit"; Catefica locality, Portugal. a, b) Lateral (a) and ventral (b) views of a rugulate fruit showing the short extension of the sessile stigma at the apex (arrows); c) Irregular surface of fruit that probably reflects an irregular endocarp; note the isodiametric outlines of the epidermal cells; d) Semi-tectate reticulate pollen grains embedded in the remains of a secretion on the stigmatic surface. Specimen, Catefica 154-S101291 (a–d). Scale bars = 300 Μm (a, b), 100 Μm (c), 6 Μm (d).
Text-fig. 22. Scanning electron microscope (SEM, a–c) and synchrotron radiation X-ray tomographic microscopy (SRXTM, d) images of Ibericarpus cuneiformis gen. et sp. nov.; Catefica locality, Portugal. a) Fruiting axis bearing an elongated receptacle with numerous diamond-shaped scars from detached fruitlets; note the absence of scars from bracts, tepals or stamens at the transition to the fruitlet scars and the stalk (arrow); b) Group of ten fruitlets detached from fruiting axis in (a) showing apical stigmatic region and distinctive bulging isodiametric epidermal cells; c) Detached fruitlet showing apical stigmatic region; d) Volume rendering of three adhering fruits showing apical stigmatic region and distinctive bulging isodiametric epidermal cells. Specimens, Catefica MM75-P0477 (a, b), Catefica 49-S115852 (c), Catefica 50-S174907 (d). Scale bars = 300 Μm (a–d). in The Early Cretaceous Mesofossil Flora Of Catefica, Portugal: Angiosperms
Text-fig. 22. Scanning electron microscope (SEM, a–c) and synchrotron radiation X-ray tomographic microscopy (SRXTM, d) images of Ibericarpus cuneiformis gen. et sp. nov.; Catefica locality, Portugal. a) Fruiting axis bearing an elongated receptacle with numerous diamond-shaped scars from detached fruitlets; note the absence of scars from bracts, tepals or stamens at the transition to the fruitlet scars and the stalk (arrow); b) Group of ten fruitlets detached from fruiting axis in (a) showing apical stigmatic region and distinctive bulging isodiametric epidermal cells; c) Detached fruitlet showing apical stigmatic region; d) Volume rendering of three adhering fruits showing apical stigmatic region and distinctive bulging isodiametric epidermal cells. Specimens, Catefica MM75-P0477 (a, b), Catefica 49-S115852 (c), Catefica 50-S174907 (d). Scale bars = 300 Μm (a–d).
Text-fig. 6. Taimyria triassica NAUGOLNYKH et MOGUTCHEVA gen. et sp. nov., holotype 4287/6. Epidermal-cuticular structure of upper surface of seed-bearing capsule. a–c, e–g: cuticles of upper surface of seed-bearing capsule, b – detail of (a), notice small white spot at picture center, which could be interpreted as scar of small monocellular trichome; d: conducting strand going to seed scar. Locality: Tsvetkov Cape; Lower Triassic, Induan; Keshin Formation. Scale bar 200 µm (a, c, d, g), 100 µm (e, f). in Taimyria Gen. Nov., A New Genus Of Evolutionary Advanced Gymnosperms From Triassic Of The Taimyr Peninsula, Siberia, Russia
Text-fig. 6. Taimyria triassica NAUGOLNYKH et MOGUTCHEVA gen. et sp. nov., holotype 4287/6. Epidermal-cuticular structure of upper surface of seed-bearing capsule. a–c, e–g: cuticles of upper surface of seed-bearing capsule, b – detail of (a), notice small white spot at picture center, which could be interpreted as scar of small monocellular trichome; d: conducting strand going to seed scar. Locality: Tsvetkov Cape; Lower Triassic, Induan; Keshin Formation. Scale bar 200 µm (a, c, d, g), 100 µm (e, f).
Text-fig. 5. Taimyria triassica NAUGOLNYKH et MOGUTCHEVA gen. et sp. nov., holotype 4287/6. a–d: epidermal-cuticular structure of upper surface of seed-bearing capsule. Locality: Tsvetkov Cape; Lower Triassic, Induan; Keshin Formation. Scale bar 100 µm (a, c, d), 50 µm (b). in Taimyria Gen. Nov., A New Genus Of Evolutionary Advanced Gymnosperms From Triassic Of The Taimyr Peninsula, Siberia, Russia
Text-fig. 5. Taimyria triassica NAUGOLNYKH et MOGUTCHEVA gen. et sp. nov., holotype 4287/6. a–d: epidermal-cuticular structure of upper surface of seed-bearing capsule. Locality: Tsvetkov Cape; Lower Triassic, Induan; Keshin Formation. Scale bar 100 µm (a, c, d), 50 µm (b).
Text-fig. 7. Taimyria triassica NAUGOLNYKH et MOGUTCHEVA gen. et sp. nov., holotype 4287/6. Line drawing of epidermal cuticle of upper surface of seed-bearing disc showing stoma. Locality: Tsvetkov Cape; Lower Triassic, Induan; Keshin Formation. Scale bar 100 µm. in Taimyria Gen. Nov., A New Genus Of Evolutionary Advanced Gymnosperms From Triassic Of The Taimyr Peninsula, Siberia, Russia
Text-fig. 7. Taimyria triassica NAUGOLNYKH et MOGUTCHEVA gen. et sp. nov., holotype 4287/6. Line drawing of epidermal cuticle of upper surface of seed-bearing disc showing stoma. Locality: Tsvetkov Cape; Lower Triassic, Induan; Keshin Formation. Scale bar 100 µm.
Text-fig. 4. Taimyria triassica NAUGOLNYKH et MOGUTCHEVA gen. et sp. nov., holotype 4287/6. a: line drawing explaining female cone morphology after holotype; b: suggested reconstruction showing arrangement and vascularization of seed-bearing discs (left), and section through seed-bearing discs exhibiting seed attachment and marginal limb structure (right); c: seed scar structure (after Textfig. 3c), 1 – subepidermal and epidermal tissues under the cuticle, 2 – coaly tissues of mesophyll. Oval form at seed scar center is possible exit of conducting strand. Locality: Tsvetkov Cape; Lower Triassic, Induan; Keshin Formation. Scale bar 1 cm (a, b), 100 µm (c). in Taimyria Gen. Nov., A New Genus Of Evolutionary Advanced Gymnosperms From Triassic Of The Taimyr Peninsula, Siberia, Russia
Text-fig. 4. Taimyria triassica NAUGOLNYKH et MOGUTCHEVA gen. et sp. nov., holotype 4287/6. a: line drawing explaining female cone morphology after holotype; b: suggested reconstruction showing arrangement and vascularization of seed-bearing discs (left), and section through seed-bearing discs exhibiting seed attachment and marginal limb structure (right); c: seed scar structure (after Textfig. 3c), 1 – subepidermal and epidermal tissues under the cuticle, 2 – coaly tissues of mesophyll. Oval form at seed scar center is possible exit of conducting strand. Locality: Tsvetkov Cape; Lower Triassic, Induan; Keshin Formation. Scale bar 1 cm (a, b), 100 µm (c).
Safety and Efficacy Study of Sapanisertib in Combination With Exemestane or Fulvestrant in Postmenopausal Women With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/H
ClinicalTrials.gov study NCT02049957. IPD Sharing: YES. Countries: 3. Publications: 1.
DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]
ClinicalTrials.gov study NCT03529110. IPD Sharing: YES. Countries: 15. Publications: 9.
DS-1205c With Gefitinib for Metastatic or Unresectable Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT03599518. IPD Sharing: YES. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.