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datasets available to search
ShareScore release 0.9.0
Dataset results
37 results for “epigenetic diversity”
Increased epigenetic diversity and transient epigenetic memory in response to salinity stress in Thlaspi arvense
<p>Epigenetic diversity could play an important role in adaptive evolution of organisms, especially for plant species occurring in new and stressful environments. Thlaspi arvense (pennycress), a valuable oilseed crop, is widespread in temperate regions of the northern hemisphere. In this study, we investigated the effect of salinity stress on the epigenetic variation of DNA methylation and epigenetic stress memory in pennycress using methylation-sensitive amplification polymorphism (MSAP) markers. We examined how the status of DNA methylation changes across individuals in response to salinity stress and whether such an effect of maternal stress could be transferred to offspring for one or two generations in non-stressed environments. Our results based on 306 epiloci indicated no consistent change of DNA methylation status in specific epiloci across individuals within the same conditions. In contrast, we found that the epigenetic diversity at population level increased significantly in response to the stimulation of salinity stress; and this "stimulation effect" could be transferred partially in the form of stress memory to at least two generations of offspring in non-stressed environments. In addition, we observed a parallel change in functionally important traits, i.e. phenotypic variation was significantly higher in plants grown under salinity stress compared with those of control groups. Taken together, our results provide novel clues for the increased spontaneous epimutation rate in response to stress in plants, of potential adaptive significance.</p>
Increased epigenetic diversity and transient epigenetic memory in response to salinity stress in Thlaspi arvense
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Data from: Local parasite pressures and host genotype modulate epigenetic diversity in a mixed-mating fish
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Data from: Epigenetic variation predicts regional and local intraspecific functional diversity in a perennial herb
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Epigenetic diversity underlying seasonal and annual variations in brown planthopper (BPH) populations as revealed by methylation-sensitive restriction assay
<p>Raw data files for the image analysis.</p>
Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH [RNA-seq]
GEO Series GSE128337. Mus musculus. 57 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic and in vivo comparison of diverse mesenchymal stromal cell sources reveals an endochonrdal signature for human hematopoietic niche formation
GEO Series GSE57151. Homo sapiens. 11 samples. Type: Expression profiling by array.
Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes
GEO Series GSE97222. Mus musculus. 18 samples. Type: Genome binding/occupancy profiling by array.
Single nucleus pituitary transcriptomic and epigenetic landscape reveals human stem cell heterogeneity with diverse regulatory mechanisms (snRNA-seq)
GEO Series GSE178452. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Cell-type specific DNA methylome signatures reveal epigenetic mechanisms for neuronal diversity and neurodevelopmental disorder
GEO Series GSE191211. Mus musculus. 20 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Single nucleus pituitary transcriptomic and epigenetic landscape reveals human stem cell heterogeneity with diverse regulatory mechanisms (snMultiome)
GEO Series GSE178453. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Single nucleus pituitary transcriptomic and epigenetic landscape reveals human stem cell heterogeneity with diverse regulatory mechanisms (snATAC-seq)
GEO Series GSE178451. Homo sapiens. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging [Bisulfite-Seq]
GEO Series GSE83947. Mus musculus. 1244 samples. Type: Methylation profiling by high throughput sequencing.
Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories (scRNA-seq)
GEO Series GSE165314. Mus musculus. 1929 samples. Type: Expression profiling by high throughput sequencing.
Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH [ATAC-seq]
GEO Series GSE128335. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH
GEO Series GSE128338. Mus musculus. 100 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
GEO Series GSE89275. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories (ATAC-seq)
GEO Series GSE165312. Mus musculus. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH [scRNA-seq]
GEO Series GSE128334. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Single nucleus pituitary transcriptomic and epigenetic landscape reveals human stem cell heterogeneity with diverse regulatory mechanisms
GEO Series GSE178454. Homo sapiens. 15 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.